Larvicidal activity of lipophilic extract of Hypericum carinatum (Clusiaceae) against Aedes aegypti (Diptera: Culicidae) and benzophenones determination.

Abstract:

:In this study, the larvicidal activity of an enriched fraction of the major lipophilic phenolic compounds from Hypericum carinatum Griseb. (Clusiaceae) was investigated against larvae of Aedes aegypti (Diptera: Culicidae), the main vector of dengue virus in Brazil. The larval mortality rate ranged 37.33 to 72.00 % at concentrations of 66-200 μg/mL. The effect demonstrated to be dose-dependent. The lethal concentration 50 % and confidence interval were 100 and 88-111 μg/mL, respectively. The results could be attributed to the presence of cariphenone A and cariphenone B in concentrations of 1.24 ± 0.04 and 0.56 ± 0.01 %, respectively, determined by high-performance liquid chromatography. Besides, the results reinforce the potential of genus Hypericum as source of alternative insecticides.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

da Silva FC,de Barros FM,Prophiro JS,da Silva OS,Pereira TN,de Loreto Bordignon SA,Eifler-Lima VL,von Poser GL

doi

10.1007/s00436-013-3401-8

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

2367-71

issue

6

eissn

0932-0113

issn

1432-1955

journal_volume

112

pub_type

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