Abstract：
:The efficacy of a combination of ivermectin (IVM) and albendazole (ABZ) used as a chemoprophylactic treatment and as treatment of secondary hydatidosis is described for the first time. IVM treatment alone was not effective against Echinococcus granulosus, either when the protoscolices were recently inoculated or when they had developed to the metacestode stage. However, the efficacy of IVM and ABZ when used in combination as a prophylactic treatment was 95.72% and 87% with respect to the number and the wet weight of cysts, respectively. These results were higher than in the treatment of secondary hydatidosis, which were 44.8% and 45.26%, respectively. The ultrastructural changes in the germinal layer of the cysts after the treatments are also described.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Moreno MJ,Casado N,Urrea-París MA,Rodríguez-Caabeiro Fdoi
10.1007/s00436-002-0623-6subject
Has Abstractpub_date
2002-06-01 00:00:00pages
563-7issue
6eissn
0932-0113issn
1432-1955journal_volume
88pub_type
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