Abstract：
:Cytokine-induced apoptosis inhibitor (CIAP) is a novel antiapoptotic molecule, which is different to inhibitor of apoptosis protein or B-cell lymphoma 2. CIAP was originally identified as a molecule that conferred resistance to apoptosis induced by growth factor starvation. However, it remains to be undercharacterized in schistosomes. Here, we molecularly characterize a novel cytokine-induced apoptosis inhibitor from Schistosoma japonicum (SjCIAP). The transcription of the SjCIAP occurred at all of developmental stages investigated including eggs, cercariae, schistosomula, and adult schistosomes. Functional assay indicated that the SjCIAP could inhibit caspase activity in either human cell lines or schistosome lysates. Our preliminary results suggest that the SjCIAP may play important roles in parasitic living and development by regulating apoptosis, and drug target of SjCIAP might be a potential for schistosomiasis control.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Luo R,Zhou C,Shi Y,Zhao J,Cheng Gdoi
10.1007/s00436-012-3086-4subject
Has Abstractpub_date
2012-12-01 00:00:00pages
2317-24issue
6eissn
0932-0113issn
1432-1955journal_volume
111pub_type
杂志文章abstract：:A multicomponent DNA vaccine, encoding Toxoplasma gondii GRA1 and SAG1, was constructed and tested for its ability to confer protection. BALB/c mice were challenged with tachyzoites of the virulent T. gondii RH strain at 4 weeks following the last immunization, and immune responses and survival times were observed. Th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3047-y
更新日期：2012-11-01 00:00:00
abstract：:Ticks and tick-borne diseases (TBDs) continue to pose an insidious and ever-present threat to livestock and livelihoods across the globe. Two of the most significant TBDs of cattle in Africa are heartwater and babesioisis, caused by Ehrlichia ruminantium and Babesia bigemina respectively. Both pathogens are endemic in...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06204-1
更新日期：2019-03-01 00:00:00
abstract：:The histopathological examination of 11 mesenteric lymph nodes from adult sheep infected with immature stages of Linguatula serrata revealed acute and chronic lesions with the presence of bacterial colonies and yeast cells. Bacteria were mainly present in acute, hemorrhagic, or necrotic lesions while yeast cells were ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-0951-2
更新日期：2008-05-01 00:00:00
abstract：:The present work was aimed at evaluating the "in vitro" efficacy of different concentrations of thymol on engorged nymphs and females of Rhipicephalus sanguineus. The nymphs were separated in seven groups and immersed in different concentrations of thymol (0.25%, 0.5%, 1.0%, 1.5%, and 2.0%) for 5 min. A control group ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1530-x
更新日期：2009-10-01 00:00:00
abstract：:In the present study, we described a new species of Myxidium Bütschli, 1882, obtained from the gallbladder of Spinibarbus sinensis (Bleeker, 1871) from the Jialing River in Chongqing, China. Myxidium spinibarba sp. nov. was identified based on morphological and SSU rDNA sequence data. The mature myxospores were fusifo...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06644-0
更新日期：2020-05-01 00:00:00
abstract：:The bioassay-guided phytochemical investigation of the leaf extract of Serjania yucatanensis, a woody climbing plant endemic to the Yucatan peninsula, led to the identification of a mixture of a triterpene [lup-20(29)-en-3-one] and an oxygenated sesquiterpene (β-caryophyllene oxide), as that responsible for the origin...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-2861-6
更新日期：2012-07-01 00:00:00
abstract：:In frozen sections of the acanthocephalan Pomphorhynchus laevis, which is a frequent intestinal parasite of cyprinid and salmonid fishes, leucine aminopeptidase (APase) was localized histochemically in outer parts of the presomal bulbus as well as in all layers and most nuclei of the metasomal body wall. Enzyme activi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00932697
更新日期：1994-01-01 00:00:00
abstract：:Introduced Siberian chipmunks Eutamias sibiricus have been reported to be important reservoirs for human Lyme disease, as they may host high numbers of hard ticks carrying Borrelia spp. and other pathogens. In the present study, we assessed the prevalence of Borrelia spp. and other pathogenic bacteria in ectoparasite ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6022-4
更新日期：2018-10-01 00:00:00
abstract：:Human toxocariasis may be acquired by eating raw chicken liver. However, there are no reports on the prevalence of natural infection of chickens with Toxocara. The aim of this study was to evaluate the presence of anti-Toxocara antibodies as indicators of natural infection with Toxocara, in free-range chickens from Es...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4669-7
更新日期：2015-11-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360000301
更新日期：2001-01-01 00:00:00
abstract：:Thelohania montirivulorum sp. nov., a new species of microsporidian parasite, was found in a highland population of the Australian yabby, Cherax destructor. Data are presented on fine ultrastructure, developmental morphology and DNA sequence of the small subunit ribosomal DNA (SSU rDNA) and internal transcribed spacer...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-003-0948-9
更新日期：2003-10-01 00:00:00
abstract：:The effect of pentavalent meglumine antimoniate (glucantime) on the growth kinetics of promastigotes of 13 South American Leishmania strains isolated from patients, sylvatic reservoirs, and vectors was studied. Four of five L. (Viannia) braziliensis human isolates were obtained from drug-responsive patients and one wa...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050476
更新日期：1998-09-01 00:00:00
abstract：:Strongyloides stercoralis is an intestinal nematode in humans, distributed through tropical and subtropical regions of the world. In most individuals, the infection has a chronic nature due to auto-infection at the low level. Accelerated auto-infection, mainly after an alteration in immune status, can cause a syndrome...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0531-x
更新日期：2007-08-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050138
更新日期：1996-01-01 00:00:00
abstract：:The parasite community structure of the neotropical cormorant, Phalacrocorax brasilianus, from two lagoons (Coyuca and Tres Palos) from Guerrero state, México, was examined. Fourteen species of adult helminths (6,391 individuals) from 48 cormorants were identified: 9 digeneans, 1 acanthocephalan, 1 cestode, and 3 nema...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2377-5
更新日期：2011-11-01 00:00:00
abstract：:Metazoan parasites of guilds of benthic snails and crustaceans and of four fish families--Gobiidae, Gasterosteidae, Syngnathidae, and Zoarcidae--were investigated off the brackish Salzhaff area (Southwest Baltic) in the semienclosed Salzhaff and the near Rerik Riff in the free Baltic. Comparisons revealed greater simi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050681
更新日期：2000-05-01 00:00:00
abstract：:Domestic cats and other felids are definitive hosts for the zoonotic protozoan parasite Toxoplasma gondii. Serology is widely used in epidemiological studies conducted to estimate the proportion of domestic cats that have encountered the parasite. However, a limited number of such studies are available from some regio...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06368-w
更新日期：2019-08-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0717-2
更新日期：2007-11-01 00:00:00
abstract：:Little information is available on the occurrence of endoparasites in pet guinea pigs (Cavia porcellus). The purpose of this study was to evaluate the prevalence of intestinal parasites in cavies kept as pets in southern Italy. Fresh fecal samples were randomly collected from 60 guinea pigs housed in pet shops or priv...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4289-7
更新日期：2015-03-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0644-1
更新日期：2002-08-01 00:00:00
abstract：:The purpose of the present paper was to analyse the association between sequences of Entamoeba histolytica and their relationship with the development of hepatic abscesses in hamsters, using a complementary DNA library for E. histolytica. From the sequences obtained, we designed oligonucleotides for amplification by P...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-0006-x
更新日期：2006-01-01 00:00:00
abstract：:In order to identify brain cell types that serve as host cells of Toxoplasma gondii encystation primary cultures from murine brain were infected and stained for neural and parasite stage-specific markers. In mixed culture inoculated with T. gondii tachyzoites, MAP2+ neurons, GFAP+ astrocytes, F4/80+ microglia, and O1+...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050311
更新日期：1997-01-01 00:00:00
abstract：:During infections, Giardia lamblia undergoes a continuous change of its major surface antigens, the variant-specific surface proteins (VSPs). Many studies on antigenic variation have been performed using G. lamblia clone GS/M-83-H7, which expresses surface antigen VSP H7. The present study was focused on the identific...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360100490
更新日期：2001-12-01 00:00:00
abstract：:This study identifies and characterizes one novel type of triactinospomyxon in oligochaete specimen of Branchiura sowerbyi Beddard collected from a fish pond used for rearing gibel carp located in Caidian Experimental Station of the Institute of Hydrobiology. It is nominated as Triactinospomyxon caidianensis type. The...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2775-8
更新日期：2012-06-01 00:00:00
abstract：:Specific anti-newborn larva antibodies present in the serum of rats chronically infected with Trichinella spiralis were incapable of inducing killing of newborn larvae by activation of normal peritoneal cells. These late antibodies blocked the cytotoxic reaction induced by early antibodies produced a few weeks after i...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050072
更新日期：1996-01-01 00:00:00
abstract：:The CSP, EMP2/MESA, MSP2, MSP3, MSP5, RAP1, RAP2, RESA1, SERA1 and SSP2/TRAP genes of Plasmodium falciparum are vaccine candidates. The hepatic phase of the infection is of major interest due to the protection induced by immunization with radiation-attenuated sporozoites. We therefore performed RT-PCR experiments to d...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-003-1061-9
更新日期：2004-04-01 00:00:00
abstract：:Leishmania has distinct epidemiological and biological characteristics and causes a variety of clinical symptoms. To understand the genetic diversity and the phylogenetic relationships among Leishmania isolates from China, 29 Leishmania isolates from different geographic origins, vectors, and hosts were analyzed using...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1814-1
更新日期：2010-05-01 00:00:00
abstract：:The outbreak of bluetongue disease in Central Europe necessitates new approaches in the identification of vectors to follow-up changes of populations of species and not of complexes. Since females of species of the complex of Culicoides obsoletus are difficult to be identified according to morphological criteria, we a...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1412-2
更新日期：2009-08-01 00:00:00
abstract：:Sarcocystis neurona is the parasite associated with equine protozoal myeloencephalitis (EPM). Recently, cats (Felis domesticus) have been implicated as a potential intermediate host in the life cycle of S. neurona. This study was initiated to determine whether cats have antibodies that react to S. neurona antigens sim...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360100503
更新日期：2002-01-01 00:00:00
abstract：:Dendrimers are repetitively branched molecules with a broad spectrum of applications, mainly for their antimicrobial properties and as nanocarriers for other molecules. Recently, our research group have synthesized and studied their activity against Acanthamoeba sp., causative agent of a severe ocular disease in human...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4205-1
更新日期：2015-02-01 00:00:00
