Abstract:
:The dynamics of production and excretion of leukotrienes by parasitic larvae of Oesophagostomum dentatum and their role for the development of the larvae were studied. Larvae were cultured in vitro to the fourth stage (L4). Leukotriene B4 (LTB4) was detected in homogenates and in supernatant of larvae, with the homogenate-protein-based values steadily decreasing during development. The homogenate-protein-based values of peptidyl leukotrienes (pepLT) remained fairly stable in both homogenates and supernatants, whereas the wormcount-based pepLT values increased significantly. The addition of diethylcarbamazine (DEC) to the culture medium straight from the beginning of culturing (12.8 or 25.5 mmol/l) reversibly hampered growth and development to L4. Application of DEC at 12.8 mmol/l beginning on day 13 of in vitro cultivation exerted no significant effect on further development to L4. LTB4 appeared to counteract the inhibition of development by DEC. The results of this study indicate that endogenous LTs participate in regulation of the growth and development of O. dentatum.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Daugschies Adoi
10.1007/s004360050138subject
Has Abstractpub_date
1996-01-01 00:00:00pages
416-22issue
5eissn
0932-0113issn
1432-1955journal_volume
82pub_type
杂志文章abstract::The Asian tiger mosquito Aedes albopictus has undergone a dramatic expansion of its range in the last few decades. Since its first detection in 2007 in Germany at the motorway A5 coming from Italy via Switzerland to Germany, it has been continuously introduced by vehicles, most probably from Italy. After a hint from a...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-5356-z
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Parasitology research
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
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journal_title:Parasitology research
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更新日期:1992-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-09-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
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