Abstract：
:We examined the in vitro effect of increasing gliotoxin concentrations on the infectivity of Toxoplasma gondii for NIH-3T3 murine fibroblasts and on Toxoplasma chymotrypsin-like activity, which is specific to the proteasome. Parasite penetration of host cells was not modified by a high gliotoxin concentration (1 microM), but replication was markedly decreased (approximately 50% inhibition by 0.5 microM gliotoxin). Gliotoxin reduced the chymotrypsin-like activity of the Toxoplasma proteasome, but five times less potently than in HeLa cells.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Paugam A,Creuzet C,Dupouy-Camet J,Roisin Pdoi
10.1007/s00436-002-0644-1subject
Has Abstractpub_date
2002-08-01 00:00:00pages
785-7issue
8eissn
0932-0113issn
1432-1955journal_volume
88pub_type
杂志文章abstract：:Trypanosoma cruzi and Trypanosoma rangeli are kinetoplastid parasites which are able to infect humans in Central and South America. Misdiagnosis between these trypanosomes can be avoided by targeting barcoding sequences or genes of each organism. This work aims to analyze the feasibility of using species-specific mark...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3872-2
更新日期：2014-06-01 00:00:00
abstract：:The outbreak of bluetongue disease in Central Europe necessitates new approaches in the identification of vectors to follow-up changes of populations of species and not of complexes. Since females of species of the complex of Culicoides obsoletus are difficult to be identified according to morphological criteria, we a...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1412-2
更新日期：2009-08-01 00:00:00
abstract：:Saprophytic soil fungi can exert ovicidal and ovistatic effects on helminths with differing degrees of efficiency. The representatives of such fungi from temperate regions, Paecilomyces lilacinus (Thom) Samson and P. marquandii (Masse) Hughes, exhibit recognized ovicidal activity on some nematodes. We evaluated the ac...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/pl00008513
更新日期：2000-10-01 00:00:00
abstract：:WD40-repeat proteins have four to eight repeating units flanked by Gly-His (GH) and Trp-Asp (WD) at both termini and folds into a beta-propeller. A polypeptide deduced from a Clonorchis sinensis cDNA clone analyzed to have seven WD40-repeats and predicted to form a beta-propeller (CsWD1). The CsWD1 protein was express...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0721-6
更新日期：2007-12-01 00:00:00
abstract：:The phylogenetic placement of gregarine parasites (Apicomplexa: Gregarinasina) within the Apicomplexa was derived by comparison of small-subunit ribosomal RNA gene sequences. Gregarine sequences were obtained from Gregarina niphandrodes Clopton, Percival, and Janovy, 1991, and Monocystis agilis Stein, 1848 (Eugregarin...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050655
更新日期：1999-11-01 00:00:00
abstract：:Experiments were undertaken to develop a serum-free medium for the in vitro cultivation of Babesia caballi, a tick-borne hemoprotozoan parasite, one of the causative agents of equine piroplasmosis. A modified HL-1 medium supplemented with horse serum, L-glutamine, antibiotics, and hypoxanthine was used. B. caballi org...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050568
更新日期：1999-05-01 00:00:00
abstract：:Chagas' disease, which is an important health problem in humans, is caused by the protozoan Trypanosoma cruzi. The cellular and molecular mechanisms, involved in the selective tropism of T. cruzi to different organs remain largely unknown. In this study we designed a PCR-based molecular diagnosis method in order to st...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0787-0
更新日期：2003-04-01 00:00:00
abstract：:Albendazole (ABZ), a widely used anthelmintic, attributes its primary metabolite-albendazole sulfoxide (ABZSO)-as an effective agent against helminthes. For a purpose of long-lasting releasing ABZSO in a special lesion, the present study successfully manufactured ABZSO-loaded thermo-sensitive hydrogel, which was prove...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5365-y
更新日期：2017-03-01 00:00:00
abstract：:Gray mullet (Mugilidae) occur in all seas and are farmed widely around the world, and thus, the risk of their parasites spreading through transport of aquaculture seed is a serious concern. Among others, gray mullets typically host a diversity of myxosporeans, a group in which spore morphometrics of genera has been co...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6151-9
更新日期：2019-01-01 00:00:00
abstract：:An easy and rapid tool for the individual identification of Haemonchus species in domestic ruminants might be very useful in the study of natural populations, especially when two (or three) species are sympatric. Techniques based on cytology, cuticular-ridge patterns, sublateral hypodermic chords, or molecular biology...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050213
更新日期：1997-01-01 00:00:00
abstract：:Toxoplasma gondii, the agent of toxoplasmosis, is an intracellular parasite that can infect a wide range of vertebrate hosts. Toxoplasmosis causes severe damage to immunocompromised hosts and its treatment is mainly based on the combination of pyrimethamine and sulfadiazine, which causes relevant side effects primaril...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06493-6
更新日期：2019-12-01 00:00:00
abstract：:Exposure to viable Acanthamoeba may cause fatal encephalitis and blinding keratitis in humans. Quantification of environmental Acanthamoeba by a reliable analytical assay is essential to assess the risk of human exposure and efficacy of control measures (e.g., superheating). Two DNA binding dyes (ethidium monoazide (E...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3556-3
更新日期：2013-11-01 00:00:00
abstract：:The development of the metacestode stages of Arostrilepis microtis (Eucestoda: Hymenolepididae) studied on the basis of an experimental infection of springtails (Collembola: Entomobryidae) is described for the first time. A complete description of the ontogeny from oncosphere to fully a developed metacestode is given....
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5929-0
更新日期：2018-08-01 00:00:00
abstract：:Little information is available on the occurrence of endoparasites in pet guinea pigs (Cavia porcellus). The purpose of this study was to evaluate the prevalence of intestinal parasites in cavies kept as pets in southern Italy. Fresh fecal samples were randomly collected from 60 guinea pigs housed in pet shops or priv...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4289-7
更新日期：2015-03-01 00:00:00
abstract：:A comprehensive icthyoparasotological survey among estuarine and freshwater fishes of West Bengal, India revealed Trichodinella sunderbanensis sp. nov. and Trichodina acuta Lom, 1961 from an estuarine fish Mystus gulio (Hamilton, 1822) from the Vidyadhari river; Trichodina nandusi sp. nov. from a freshwater fish, Nand...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3234-x
更新日期：2013-03-01 00:00:00
abstract：:The effect of lemon oil (Citrus limon) on Sarcoptes scabiei var. cuniculi was evaluated in vitro and in vivo. The mite samples were collected from naturally infected rabbits. The lemon oil was prepared in six concentrations by dilution with distilled water (2.5, 5, 10, 20, 50, and 100 %). In vitro application was done...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5056-8
更新日期：2016-08-01 00:00:00
abstract：:Three actinosporean types--raabeia, aurantiactinomyxon, and guyenotia--from the oligochaete Branchiura sowerbyi Beddard collected from a crucian carp (Carassius auratus gibelio) pond are described in this report. Compared with the actinospores described previously, the raabeia type presents similar spore shape with th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3306-6
更新日期：2013-04-01 00:00:00
abstract：:Monogamy is a mating system with pairs made of only one male and only one female. But social monogamy cannot inevitably imply the sexual exclusivity between mates, which is yet the case in genetic monogamy on which the offspring results only from the observed pair. The genetic monogamy is today considered as an except...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1225-8
更新日期：2009-01-01 00:00:00
abstract：:Interferon-tau (IFN-tau) treatment of Trichinella spiralis-infected BALB/c mice was investigated. The therapeutic regimen consisted of daily intraperitoneal injection of 10(4) U murine IFN-tau for 7 days, starting at 2 weeks post-infection. Striated muscle samples (diaphragm, thigh) were collected at 4, 8 and 12 weeks...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931641
更新日期：1991-01-01 00:00:00
abstract：:The purified metalloprotease and the partially purified cysteine protease from pathogenic Cryptobia salmositica were characterized. Using haemoglobin gel electrophoresis, we detected five enzymatic bands in crude parasite lysate; one protease (200 kDa) yielded a metalloprotease band and other four, cysteine protease b...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050435
更新日期：1998-06-01 00:00:00
abstract：:Ticks are hematophagous ectoparasites which can transmit several diseases to the host during their feeding process. When ticks mechanically damage the tissue, they eventually induce inflammatory responses on the skin spot where they are fixed. One of the alternatives to control these ectoparasites is the use of chemic...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3422-3
更新日期：2013-07-01 00:00:00
abstract：:Free-living amoebae (FLA) are opportunistic and ubiquitous protozoa that are widely found in various environmental sources. They are known to cause serious human infections. The aim of our study was to detect FLA and Acanthamoeba spp. in hospital water circuits. Eighty-four water samples were collected over a period o...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4788-1
更新日期：2016-01-01 00:00:00
abstract：:The aims of this study are to identify Leishmania species and compare and validate internal transcribed spacers (ITS) polymerase chain reaction (PCR) assay against parasitological methods for diagnosing cutaneous leishmaniasis (CL). We used the ITS-PCR, parasite culture, and microscopic evaluation of stained smears on...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1111-4
更新日期：2008-10-01 00:00:00
abstract：:Whole sequencing of protozoan trypanosomatid genomes revealed the presence of several predicted unknown genes coding for hypothetical proteins. Pairwise, alignment-based, computational methods available online are unable to identify the function of these sequences. To detect clues to identify the function of hypotheti...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-0064-0
更新日期：2006-03-01 00:00:00
abstract：:Cystic echinococcosis is a worldwide zoonosis caused by Echinococcus granulosus. Because the methods of diagnosis and treatment for cystic echinococcosis were limited, it is still necessary to screen target proteins for the development of new anti-hydatidosis vaccine. In this study, the triosephosphate isomerase gene ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5166-3
更新日期：2016-10-01 00:00:00
abstract：:Pharmacokinetics and anthelmintic activity of topical eprinomectin in goats prevented from physical contact to others and self-grooming were studied. Sixteen approximately 7 months old male castrated German White Noble goats harbouring induced infections of gastrointestinal nematode parasites were included in the stud...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4072-9
更新日期：2014-11-01 00:00:00
abstract：:A total of 585 persons from several occupational groups (farmers, slaughterhouse staff, hunters, veterinarians) exposed to Toxocara infestations and 50 persons of a control group were tested for the presence of specific antibodies to the Toxocara canis antigen using an enzyme-linked immunosorbent assay and a western b...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1469-5
更新日期：2005-11-01 00:00:00
abstract：:In three different areas in northern Germany, hippoboscids were collected from red deer (Cervus elaphus). Typanosomatids were demonstrated in the midgut and hindgut of 9/37 Lipoptena cervi. The trypanosomatids were morphologically similar to vector forms of the subgenus Megatrypanum that had been found in tabanids at ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00928691
更新日期：1991-01-01 00:00:00
abstract：:Mosquito repellents represent a cleaner and safer alternative for population control and reduce the diseases they carry in large areas of the world. Recently, research has been focused on repellents of natural origins, both crude essential oils and their main constituents. We have observed that, although a large numbe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3827-7
更新日期：2014-05-01 00:00:00
abstract：:Analyses were made on the adenosine transporter-1 gene in Trypanosoma brucei (TbAT1), encoding a P2-like nucleoside transporter, from T. brucei brucei field stocks to investigate a possible link between the presence of mutations in this gene and isometamidium resistance. We have analysed the gene from 11 isometamidium...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0141-z
更新日期：2006-08-01 00:00:00
