Cellular reactions in the small intestine of rats after infection with Fasciola hepatica.

Abstract:

:Groups of five rats each were infected with metacercariae of Fasciola hepatica according to two experimental procedures. In the first experiment, they received 20 metacercariae 0, 1, 2 or 3 times at intervals of 4 weeks. In the second, both the inoculation dose and the interval between doses were varied. After the animals had been killed, the small intestine was prepared for histology and tissue sections were stained for the detection and quantification of mucosal mast cells (MMCs), eosinophils and goblet cells. The density of eosinophils and MMCs increased significantly with each reinfection in the first experiment; in the second, the MMC reaction reached a peak at 4 weeks post-infection (p.i.), whereas the eosinophils peaked at 4 and 17 weeks p.i. In addition, the reaction of these cells depended on the infectious dose. In both experiments, goblet cells reacted only weakly. These findings thus clearly reflect a considerable intestinal response against migrating juvenile F. hepatica. The pattern of these defence reactions in the small intestine suggests some similarities with the mechanisms of antibody-dependent cell-mediated cytotoxicity that have been shown to take place during Schistosoma mansoni reinfection.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Charbon JL,Spähni M,Wicki P,Pfister K

doi

10.1007/BF00931639

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

425-9

issue

5

eissn

0932-0113

issn

1432-1955

journal_volume

77

pub_type

杂志文章
  • Immune response and protection in mice inoculated with Leishmania amazonensis clones expressing different degrees of virulence.

    abstract::The induction of protective immunity to Leishmania amazonensis was investigated by injection of parasite clones of low and medium virulence into susceptible mice. To this end, L. amazonensis were cloned by limiting dilution and the clones' virulence was evaluated by the course of infection in susceptible mice. Clones ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360050321

    authors: da Fonseca AL,Vallochi AL,Furtado Gde C,Abrahamsohn Ide A,Lima GM

    更新日期:1997-01-01 00:00:00

  • Do the pattern and strength of species associations in ectoparasite communities conform to biogeographic rules?

    abstract::We tested whether biogeographic patterns characteristic of species diversity and composition may also apply to community assembly by investigating geographic variation in the pattern (PSA) (aggregation versus segregation) and strength of species associations (SSA) in flea and mite communities harbored by small mammali...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-019-06255-4

    authors: Krasnov BR,Shenbrot GI,Korallo-Vinarskaya NP,Vinarski MV,van der Mescht L,Warburton EM,Khokhlova IS

    更新日期:2019-04-01 00:00:00

  • Occurrence and regional distribution of Aelurostrongylus abstrusus in cats in Germany.

    abstract::Infections with the metastrongyloid nematode Aelurostrongylus abstrusus in cats have been reported sporadically from Germany. To assess the occurrence and regional geographical distribution of A. abstrusus in Germany, faecal samples from 391 cats with symptoms of respiratory disease were collected from December 2009 t...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-012-3207-0

    authors: Barutzki D,Schaper R

    更新日期:2013-02-01 00:00:00

  • Ultrastructural observations on the elusive subtegumental cells of the viviparous gill monogenean, Macrogyrodactylus clarii.

    abstract::The ultrastructure of the tegument, including putative subtegumental cells, of the monogenean gill parasite Macrogyrodactylus clarii is described for the first time. The lateral cells are secretory in nature and can be classified into four types: T1 producing elongated, electron-dense, bodies (t1); T2 manufacturing el...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-006-0448-9

    authors: El-Naggar MM,Cable J

    更新日期:2007-06-01 00:00:00

  • Life-cycle description and comparison of Diplostomum spathaceum (Rudolphi, 1819) and D. pseudobaeri (Razmaskin & Andrejak, 1978) from rainbow trout (Oncorhynchus mykiss Walbaum) maintained in identical hosts.

    abstract::Precise identification of members of the genus Diplostomum is difficult in that many larval stages have been described and named separately from their adult forms. In this study, the life cycles of two Diplostomum spp. were established using metacercariae obtained from the eyes of rainbow trout. The parasites were ide...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00931794

    authors: Field JS,Irwin SW

    更新日期:1995-01-01 00:00:00

  • Structure of capsule surrounding acanthocephalans Corynosoma strumosum in paratenic hosts of three species.

    abstract::Morphology of capsules surrounding acanthocephalan Corynosoma strumosum in paratenic hosts (sea fishes of three species from the northern part of the Sea of Okhotsk) was studied. A thick layer of glycocalyx is formed on the surface of acanthocephalan's tegument in smelts Osmerus mordax dentex and Hypomesus olidus; the...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-010-2088-3

    authors: Skorobrechova EM,Nikishin VP

    更新日期:2011-02-01 00:00:00

  • First description of an apical epidermis cone in Paratenuisentis ambiguus (Acanthocephala: Eoacanthocephala) and its phylogenetic implications.

    abstract::The proboscis apex of the eoacanthocephalan parasite Paratenuisentis ambiguus was studied, using electron and light microscopy, for a better understanding of the parasite's attachment at the intestinal wall of its definitive hosts (Anguilla rostrata and A. anguilla). The results suggest the presence of an epidermis co...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/pl00008583

    authors: Herlyn H

    更新日期:2001-04-01 00:00:00

  • Intraspecies variation of Brugia spp. in cat reservoirs using complete ITS sequences.

    abstract::The internal transcribed spacer (ITS) region was used to study the intraspecies variation of Brugia spp. in cat reservoirs. Blood specimens from seven naturally infected cats were collected from two different geographical brugian-endemic areas in Thailand. The DNAPAR tree of these Brugia spp. was constructed using a m...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-009-1352-x

    authors: Areekit S,Singhaphan P,Khuchareontaworn S,Kanjanavas P,Sriyaphai T,Pakpitchareon A,Khawsak P,Chansiri K

    更新日期:2009-06-01 00:00:00

  • Return to sender: use of Plasmodium ER retrieval sequences to study protein transport in the infected erythrocyte and predict putative ER protein families.

    abstract::We have investigated how knowledge of endoplasmic reticulum (ER) retrieval signals can be used to study specific trafficking pathways in the malaria-infected erythrocyte. We show that addition of various lumenal ER retrieval signals to soluble green fluorescent protein (GFP) chimaera causes retrieval of the fusion pro...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-009-1397-x

    authors: Külzer S,Gehde N,Przyborski JM

    更新日期:2009-06-01 00:00:00

  • Characterization and bioassay for larvicidal activity of Anacardium occidentale (cashew) shell waste fractions against dengue vector Aedes aegypti.

    abstract::Recent studies regarding the harmful effects of synthetic larvicides initiated the need to investigate for unconventional measures that are environmentally safe and target-specific against Aedes aegypti larvae. Thus, the main objectives of the study are to evaluate the larvicidal toxicity of the solvent fractions of A...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-015-4598-5

    authors: Torres RC,Garbo AG,Walde RZ

    更新日期:2015-10-01 00:00:00

  • How does supplementary feeding affect endoparasite infection in wild boar?

    abstract::Supplementary feeding is widely used in game management but may aid the transmission of parasites. Firstly, feeding sites attract animals and may be regarded as high-risk areas for parasite transmission. Secondly, high host population densities resulting from and supported by supplementary feeding, as well as accumula...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5512-0

    authors: Oja R,Velström K,Moks E,Jokelainen P,Lassen B

    更新日期:2017-08-01 00:00:00

  • A Taenia solium metacestode factor nonspecifically inhibits cytokine production.

    abstract::Studies of the immune response in chronic helminth infections suggest that parasites modulate the host's immune response. Taenia solium metacestodes, in particular, produce molecules that down-regulate cell-mediated immunity. We have described a small RNA peptide termed metacestode factor (MF) that depresses the murin...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360050367

    authors: Arechavaleta F,Molinari JL,Tato P

    更新日期:1998-01-01 00:00:00

  • Survey for Toxoplasma gondii by PCR detection in meat for human consumption in Colombia.

    abstract::The overall risk for toxoplasmosis in meat produced in Colombia is unknown. We analyzed by PCR assay meat samples for human consumption in two types of plants in Colombia: 120 samples from class I plants (60 samples from chicken, 30 from swine and 30 from beef) and 60 from class II plants (30 samples from beef and 30 ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-015-4790-7

    authors: Franco-Hernandez EN,Acosta A,Cortés-Vecino J,Gómez-Marín JE

    更新日期:2016-02-01 00:00:00

  • Erratum to: inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.

    abstract::A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism. The cytochrome P450 (CYP 450) enzyme pathway was inhibited using ketoconazole (KTZ) to see whether a TCBZ-resistant isolate could be made more sensitive to TCB...

    journal_title:Parasitology research

    pub_type: 更正并重新发布的文章,杂志文章

    doi:10.1007/s00436-011-2554-6

    authors: Devine C,Brennan GP,Lanusse CE,Alvarez LI,Trudgett A,Hoey E,Fairweather I

    更新日期:2011-10-01 00:00:00

  • Photodynamic control of human pathogenic parasites in aquatic ecosystems using chlorophyllin and pheophorbid as photodynamic substances.

    abstract::When used at low concentrations and added to the water body, water-soluble chlorophyllin (resulting from chlorophyll after removal of the phytol) and pheophorbid (produced from chlorophyllin by acidification) are able to kill mosquito larvae and other small animals within a few hours under exposure of solar radiation....

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-008-1235-6

    authors: Wohllebe S,Richter R,Richter P,Häder DP

    更新日期:2009-02-01 00:00:00

  • Genetic uniqueness of Cryptosporidium parvum from dairy calves in Colombia.

    abstract::Fecal specimens from 432 pre-weaned calves younger than 35 days were collected over a 2-year period (2010-2012) from 74 dairy cattle farms in the central area of Colombia. These samples were microscopically examined for the presence of Cryptosporidium oocysts, and positive specimens were selected for molecular examina...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-018-5818-6

    authors: Avendaño C,Ramo A,Vergara-Castiblanco C,Sánchez-Acedo C,Quílez J

    更新日期:2018-05-01 00:00:00

  • Molecular characterisation of Hepatozoon aegypti Bashtar, Boulos & Mehlhorn, 1984 parasitising the blood of Spalerosophis diadema (Serpentes: Colubridae).

    abstract::Hepatozoon aegypti Bashtar, Boulos & Mehlhorn, 1984 was first described from the blood of the diadem snake (Spalerosophis diadema) in Egypt. During an investigation of the diversity of reptilian haemogregarines in Saudi Arabia, seven diadem snakes (100% of the sample) were found to be highly parasitised by H. aegypti,...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-018-6006-4

    authors: Abdel-Haleem HM,Mansour L,Holal M,Qasem MAA,Al-Quraishy S,Abdel-Baki AS

    更新日期:2018-10-01 00:00:00

  • Immunoblot for the detection of Ascaris suum-specific antibodies in patients with visceral larva migrans (VLM) syndrome.

    abstract::Visceral larva migrans (VLM) syndrome caused by Toxocara canis larvae was first described in the 1950s. The role of other nematode larvae, i.e. the pig roundworm Ascaris suum as a causative agent of visceral larva migrans-associated symptoms like general malaise, cough, liver dysfunction, hypereosinophilia with hepato...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-014-4196-y

    authors: Schneider R,Obwaller A,Auer H

    更新日期:2015-01-01 00:00:00

  • Thelohania montirivulorum sp. nov. (Microspora: Thelohaniidae), a parasite of the Australian freshwater crayfish, Cherax destructor (Decapoda: Parastacidae): fine ultrastructure, molecular characteristics and phylogenetic relationships.

    abstract::Thelohania montirivulorum sp. nov., a new species of microsporidian parasite, was found in a highland population of the Australian yabby, Cherax destructor. Data are presented on fine ultrastructure, developmental morphology and DNA sequence of the small subunit ribosomal DNA (SSU rDNA) and internal transcribed spacer...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-003-0948-9

    authors: Moodie EG,Le Jambre LF,Katz ME

    更新日期:2003-10-01 00:00:00

  • Characterizations and bioactivities of abendazole sulfoxide-loaded thermo-sensitive hydrogel.

    abstract::Albendazole (ABZ), a widely used anthelmintic, attributes its primary metabolite-albendazole sulfoxide (ABZSO)-as an effective agent against helminthes. For a purpose of long-lasting releasing ABZSO in a special lesion, the present study successfully manufactured ABZSO-loaded thermo-sensitive hydrogel, which was prove...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-016-5365-y

    authors: Feng Y,Wang F,Zhang XW,Bhutani H,Ye B

    更新日期:2017-03-01 00:00:00

  • Three actinosporean types (Myxozoa) from the oligochaete Branchiura sowerbyi in China.

    abstract::Three actinosporean types--raabeia, aurantiactinomyxon, and guyenotia--from the oligochaete Branchiura sowerbyi Beddard collected from a crucian carp (Carassius auratus gibelio) pond are described in this report. Compared with the actinospores described previously, the raabeia type presents similar spore shape with th...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-013-3306-6

    authors: Xi BW,Zhang JY,Xie J,Pan LK,Xu P,Ge XP

    更新日期:2013-04-01 00:00:00

  • Species delimitation and phylogenetic relationships of Chinese Leishmania isolates reexamined using kinetoplast cytochrome oxidase II gene sequences.

    abstract::Leishmaniasis is a geographically widespread disease caused by protozoan parasites belonging to the genus Leishmania and transmitted by certain species of sand fly. This disease still remains endemic in China, especially in the west and northwest frontier regions. A recent ITS1 phylogeny of Chinese Leishmania isolates...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-010-2239-6

    authors: Cao DP,Guo XG,Chen DL,Chen JP

    更新日期:2011-07-01 00:00:00

  • Studies on tsetse midgut factors that induce differentiation of blood-stream Trypanosoma brucei brucei in vitro.

    abstract::An in vitro system for studying the transformation of bloodstream forms of Trypanosoma brucei brucei into procylic (midgut) forms is described. In this system, transformation of the parasites was stimulated by Glossina morsitans morsitans midgut homogenates at 27 degrees C but not at 4 degrees C. The transformation-st...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00936174

    authors: Imbuga MO,Osir EO,Labongo VL,Darji N,Otieno LH

    更新日期:1992-01-01 00:00:00

  • ACAT-1 gene rs1044925 SNP and its relation with different clinical forms of chronic Chagas disease.

    abstract::Chagas disease, caused by the protozoan Trypanosoma cruzi (T. cruzi), although discovered more than a century ago, is still a not very well-elucidated aspect. Individuals in the chronic phase of the disease may present asymptomatic clinical form or symptomatologies related to the cardiac, digestive systems, or both (m...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-019-06377-9

    authors: Carvalho TB,Padovani CR,de Oliveira Júnior LR,Latini ACP,Kurokawa CS,Pereira PCM,Dos Santos RM

    更新日期:2019-08-01 00:00:00

  • First detection and molecular identification of Entamoeba bovis from Japanese cattle.

    abstract::Thus far, Entamoeba species have been classified based on morphology such as the number of nuclei in mature cysts and their hosts. Using recently developed molecular tools, ruminant Entamoeba spp. are currently classified into four species/genotypes: E. bovis and Entamoeba ribosomal lineages (RL) 1, 2, and 4. However,...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5689-2

    authors: Matsubayashi M,Matsuura Y,Nukata S,Daizi Y,Shibahara T,Teramoto I,Matsuo T,Uni S,Hatta T,Kaneko A,Tsuji N,Sasai K

    更新日期:2018-01-01 00:00:00

  • Ultrastructural and molecular characterization of Balantidium coli isolated in the Philippines.

    abstract::Balantidium coli is a ciliated protozoon inhabiting the colon of swine, rodents, horses, nonhuman primates and humans. In association with disease triggered by other infectious agents, B. coli may become a pathogenic opportunist. This study describes the isolation, cultivation, morphological as well as molecular chara...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-009-1673-9

    authors: Nilles-Bije ML,Rivera WL

    更新日期:2010-01-01 00:00:00

  • Response to repeated inoculations with Ascaris suum eggs in pigs during the fattening period. I. Studies on worm population kinetics.

    abstract::This experimental study on pigs was designed to simulate natural, long-term exposure to Ascaris suum under modern management conditions. Parasite kinetics were followed in pigs receiving A. suum eggs as repeated trickle inoculations at two dose levels beginning at a body weight of 25 kg until their slaughter at 90 kg ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00931733

    authors: Eriksen L,Nansen P,Roepstorff A,Lind P,Nilsson O

    更新日期:1992-01-01 00:00:00

  • In vitro efficacy of allicin on chicken Eimeria tenella sporozoites.

    abstract::Chicken coccidiosis is a major parasitic disease caused by Eimeria spp. It is controlled and treated using chemical anticoccidial agents. Development of partial or complete resistance toward these anticoccidials is considered a major problem in poultry industry. Allicin is an organosulfur compound produced as a result...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-015-4637-2

    authors: Alnassan AA,Thabet A,Daugschies A,Bangoura B

    更新日期:2015-10-01 00:00:00

  • Postembryonic development of Arostrilepis microtis Gulyaev et Chechulin, 1997 (Eucestoda: Hymenolepididae) in springtails (Collembola: Entomobryidae).

    abstract::The development of the metacestode stages of Arostrilepis microtis (Eucestoda: Hymenolepididae) studied on the basis of an experimental infection of springtails (Collembola: Entomobryidae) is described for the first time. A complete description of the ontogeny from oncosphere to fully a developed metacestode is given....

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-018-5929-0

    authors: Ishigenova LA,Berezina OG,Makarikov AA

    更新日期:2018-08-01 00:00:00

  • Historic importance of some aspects of research by O. Wilford Olsen on hookworms (Uncinaria lucasi) in northern fur seals (Callorhinus ursinus) and Steller sea lions (Eumatopias jubatus) in 1951 on St. Paul Island, Alaska.

    abstract::The purpose of this paper is to disseminate, more widely, certain historically important aspects of research by O. Wilford Olsen on hookworms (Uncinaria lucasi) in northern fur seals (Callorhinus ursinus) and Steller sea lions (Eumatopias jubatus) in 1951 on St. Paul Island, Alaska. Highly meaningful facets of the res...

    journal_title:Parasitology research

    pub_type: 历史文章,杂志文章

    doi:10.1007/s00436-005-1309-7

    authors: Lyons ET

    更新日期:2005-03-01 00:00:00