Abstract：
:Groups of five rats each were infected with metacercariae of Fasciola hepatica according to two experimental procedures. In the first experiment, they received 20 metacercariae 0, 1, 2 or 3 times at intervals of 4 weeks. In the second, both the inoculation dose and the interval between doses were varied. After the animals had been killed, the small intestine was prepared for histology and tissue sections were stained for the detection and quantification of mucosal mast cells (MMCs), eosinophils and goblet cells. The density of eosinophils and MMCs increased significantly with each reinfection in the first experiment; in the second, the MMC reaction reached a peak at 4 weeks post-infection (p.i.), whereas the eosinophils peaked at 4 and 17 weeks p.i. In addition, the reaction of these cells depended on the infectious dose. In both experiments, goblet cells reacted only weakly. These findings thus clearly reflect a considerable intestinal response against migrating juvenile F. hepatica. The pattern of these defence reactions in the small intestine suggests some similarities with the mechanisms of antibody-dependent cell-mediated cytotoxicity that have been shown to take place during Schistosoma mansoni reinfection.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Charbon JL,Spähni M,Wicki P,Pfister Kdoi
10.1007/BF00931639subject
Has Abstractpub_date
1991-01-01 00:00:00pages
425-9issue
5eissn
0932-0113issn
1432-1955journal_volume
77pub_type
杂志文章abstract：:Infections with the metastrongyloid nematode Aelurostrongylus abstrusus in cats have been reported sporadically from Germany. To assess the occurrence and regional geographical distribution of A. abstrusus in Germany, faecal samples from 391 cats with symptoms of respiratory disease were collected from December 2009 t...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3207-0
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06381-z
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更新日期：2015-08-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章,评审
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journal_title：Parasitology research
pub_type： 杂志文章,评审
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journal_title：Parasitology research
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journal_title：Parasitology research
pub_type： 杂志文章
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journal_title：Parasitology research
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章,meta分析
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pub_type： 杂志文章
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