Abstract:
:Specific anti-newborn larva antibodies present in the serum of rats chronically infected with Trichinella spiralis were incapable of inducing killing of newborn larvae by activation of normal peritoneal cells. These late antibodies blocked the cytotoxic reaction induced by early antibodies produced a few weeks after infection. Passive transference of late serum to normal mice failed to induce protective immunity against infection by newborn T. spiralis larvae. When late immunoserum was fractionated by gel filtration, blocking activity was found only in the fraction containing IgG subclasses. By indirect immunofluorescence assay and cytotoxic reaction it was shown that blocking antibodies were specific for newborn larvae and could not be adsorbed with muscle larvae. It is concluded that the synthesis of anti-newborn larva antibodies is modulated in the course of a chronic infection: early antibodies developing shortly after infection are cytotoxic, whereas blocking antibodies predominate in the late population. Furthermore, the results suggest that during a chronic infection, resistance to reinfection may be modified.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Venturiello SM,Costantino SN,Giambartolomei GHdoi
10.1007/s004360050072subject
Has Abstractpub_date
1996-01-01 00:00:00pages
77-81issue
1eissn
0932-0113issn
1432-1955journal_volume
82pub_type
杂志文章abstract::Malaria remains a serious health problem in many parts of the world. It causes high morbidity and claims many lives in developing countries each year. Humans are generally infected by four species of malaria parasites. However, malaria infection caused by Plasmodium malariae or P. falciparum is recognized as an import...
journal_title:Parasitology research
pub_type: 杂志文章,评审
doi:10.1007/s00436-007-0650-4
更新日期:2007-10-01 00:00:00
abstract::Angiostrongylus cantonensis is an important zoonotic parasite causing eosinophilic meningitis and eosinophilic meningoencephalitis in humans. In this study, the protein expression profiles of the infective third- and pathogenic fifth-stage larvae (L3 and L5) of this parasite were compared by proteomic techniques. Isol...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-4024-4
更新日期:2014-10-01 00:00:00
abstract::A detailed study of the surface topography of the echinostome digenean Mesorchis denticulatus (Rudolphi 1802) Dietz 1909 was carried out using the scanning electron microscope. The surface area of the redia is increased by microvilli, and ciliate sensory structures are common around the mouth. The cannibalistic behavi...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00536336
更新日期:1987-01-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3354-y
更新日期:2013-05-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00536033
更新日期:1987-01-01 00:00:00
abstract::The relationships between inflammation in organs with Toxocara canis larval migration and matrix metalloproteinase-9 (MMP-9) were investigated following the infection of mice with 1,000 infective eggs. Gelatinase activity was defined by gelatin zymography, optimum pH, inhibitor specificity and Western blot analysis. M...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-004-1271-9
更新日期:2005-02-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3683-x
更新日期:2014-02-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931661
更新日期:1992-01-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-004-1120-x
更新日期:2004-06-01 00:00:00
abstract::Tryptophan-N-formylated gramicidin A, a nonhemolytic derivative of the toxic peptide antibiotic gramicidin A, has previously been shown to induce potassium leakage from Plasmodium falciparum-infected erythrocytes in vitro and to inhibit the growth of the parasite. In the present study the antimalarial activities of tw...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00932413
更新日期:1995-01-01 00:00:00
abstract::We examined the in vitro effect of increasing gliotoxin concentrations on the infectivity of Toxoplasma gondii for NIH-3T3 murine fibroblasts and on Toxoplasma chymotrypsin-like activity, which is specific to the proteasome. Parasite penetration of host cells was not modified by a high gliotoxin concentration (1 micro...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-002-0644-1
更新日期:2002-08-01 00:00:00
abstract::Tetratrichomonas didelphidis is a flagellate protozoan found in the intestine of the opossum. The parasite lives in a hostile and stressed environment, where it interacts with microorganisms and can survive under extreme conditions for growth, involving strict anaerobiosis or equilibration with air and abundance or ab...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-003-1015-2
更新日期:2004-01-01 00:00:00
abstract::Canine demodicosis is a severe and highly prevalent dermatologic disease in dogs. Pet dogs can be affected by three recognized Demodex species that can produce clinical effects. In this paper, three morphological types of Demodex mites have been isolated from Spanish dogs. A complete morphobiometrical study of each on...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-012-3067-7
更新日期:2012-11-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00932566
更新日期:1990-01-01 00:00:00
abstract::This is the first study dealing with the association between HLA alleles and cystic echinococcosis (CE) in Yemeni patients. The present study aimed to detect the association of HLA-DRB(1) alleles and susceptibility or resistance to CE in Yemeni patients by HLA-DRB(1) typing; first by HLA-DRB(1) amplification using PCR...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-1868-0
更新日期:2010-07-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-017-5386-1
更新日期:2017-03-01 00:00:00
abstract::Mosquitoes are important vectors of diseases to humans and domestic animals. Chemical control of vectors remains a main resource for the prevention and control of vector-borne diseases. Due to the development of insecticide resistance and risks to human health and the environment of synthetic compounds, the search for...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-007-0647-z
更新日期:2007-10-01 00:00:00
abstract::There are first data on nematodes of Anas platyrhynchos Linnaeus, 1758 (mallard) and Bucephala clangula Linnaeus, 1758 (common goldeneye) from Northern Europe (Ladoga Lake region). The ducks were found to be infected with nine nematode species. A. platyrhynchos hosted eight nematode species and B. clangula was host to...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-015-4697-3
更新日期:2015-10-01 00:00:00
abstract::Anopheles (Cellia) stephensi Liston 1901 is one of the major malaria vectors in the Indian subcontinent, Iran, and the Middle East. Three races in this species, namely A. stephensi stephensi (type form), A. stephensi variety mysorensis, and A. stephensi intermediate form, have earlier been reported by several investig...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-008-0930-7
更新日期:2008-06-01 00:00:00
abstract::This paper follows the study from 2013 focused on the molecular screening of mosquitoes as vectors of Dirofilaria spp. which provided the information on Aedes vexans as a potential vector of Dirofilaria repens in Slovakia. Current entomological and molecular research indicates that Ae. vexans can participate also in t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-015-4692-8
更新日期:2015-12-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-012-2829-6
更新日期:2012-07-01 00:00:00
abstract::The petroleum ether extract of Viola websteri Hemsl. (Violaceae) was investigated for its activity against chloroquine-sensitive strains of Plasmodium falciparum using the parasite lactate dehydrogenase assay method. The main antiplasmodial principles, 6-(8'Z-pentadecenyl)-salicylic acid (1) and 6-(8'Z, 11'Z, 14'Z-hep...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-008-1205-z
更新日期:2009-01-01 00:00:00
abstract::Toxocariasis is a worldwide zoonotic disease caused by the ascarid nematode Toxocara canis. The most common method available for serodiagnosis of toxocariasis is an enzyme-linked immunosorbent assay (ELISA) test using Toxocara excretory-secretory antigen (TES). The present study describes the development of IgG-ELISA ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-008-1067-4
更新日期:2008-09-01 00:00:00
abstract::During the present investigation, alterations in the intrahepatic venous and portal systems in Rattus norvegicus infected with 250, 500, and 1000 Taenia taeniaeformis eggs were studied. The corrosion cast technique was employed, which provides an extrinsic opportunity for study of the three-dimensional orientation of ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s004360050703
更新日期:2000-06-01 00:00:00
abstract::The oncomiracidium (larva) of the entobdelline Neoentobdella parvitesticulata (Monogenea: Capsalidae), adults of which parasitise the skin of the stingray Himantura fai (Dasyatidae) at Heron Island, Great Barrier Reef, Queensland, Australia, is described. The larva undergoes precocious development (progenesis) in the ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-005-1399-2
更新日期:2005-07-01 00:00:00
abstract::Over the past decade, advances in proteomic and mass spectrometry techniques and the sequencing of the Plasmodium falciparum genome have led to an increasing number of studies regarding the parasite proteome. However, these studies have focused principally on parasite protein expression, neglecting parasite-induced va...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2521-2
更新日期:2012-02-01 00:00:00
abstract::A survey of the myxosporean fauna of Australian marine fishes revealed the presence of three previously unreported species of Unicapsula (Multivalvulida: Trilosporidae) from sites off Southeast Queensland, off Lizard Island on the Great Barrier Reef, Queensland, and from Jurien Bay in Western Australia. Morphometric d...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3467-3
更新日期:2013-08-01 00:00:00
abstract::A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism. The cytochrome P450 (CYP 450) enzyme pathway was inhibited using ketoconazole (KTZ) to see whether a TCBZ-resistant isolate could be made more sensitive to TCB...
journal_title:Parasitology research
pub_type: 更正并重新发布的文章,杂志文章
doi:10.1007/s00436-011-2554-6
更新日期:2011-10-01 00:00:00
abstract::A total of 15 mixtures involving 9 different stocks attributed to the 19/20, 32 and 39 major clonal genotypes of Trypanosoma cruzi were used to infect third-instar nymphs of Triatoma infestans via an artificial feeding device. Three biological parameters were considered: (1) the percentage of infected insects (%II), (...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s004360050409
更新日期:1998-05-01 00:00:00
abstract::The essential oil of Cananga odorata flowers was evaluated for oviposition-deterrent, ovicidal, insecticidal, and repellent activities toward three mosquito species: Aedes aegypti, Anopheles dirus, and Culex quinquefasciatus. Oviposition deterrence of the oil was evaluated on gravid females using oviposition deterrenc...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-015-4699-1
更新日期:2015-12-01 00:00:00