Bioassay-guided isolation of antiplasmodial anacardic acids derivatives from the whole plants of Viola websteri Hemsl.

Abstract:

:The petroleum ether extract of Viola websteri Hemsl. (Violaceae) was investigated for its activity against chloroquine-sensitive strains of Plasmodium falciparum using the parasite lactate dehydrogenase assay method. The main antiplasmodial principles, 6-(8'Z-pentadecenyl)-salicylic acid (1) and 6-(8'Z, 11'Z, 14'Z-heptadecatrienyl)-salicylic acid (2), have been isolated from V. websteri for the first time. This is the first report on the antiplasmodial activity of the compounds from V. websteri.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Lee SJ,Park WH,Moon HI

doi

10.1007/s00436-008-1205-z

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

463-6

issue

2

eissn

0932-0113

issn

1432-1955

journal_volume

104

pub_type

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