Abstract:
:Sarcocystis neurona is the parasite associated with equine protozoal myeloencephalitis (EPM). Recently, cats (Felis domesticus) have been implicated as a potential intermediate host in the life cycle of S. neurona. This study was initiated to determine whether cats have antibodies that react to S. neurona antigens similar to antibodies from horses with EPM, and to evaluate the role of cats as intermediate hosts in the parasite's life cycle. Nine feral cats were used for analysis. Only one had antibodies reacting to S. neurona antigens. Muscle tissue from this cat, with detectable sarcocysts in the tongue, was fed to an opossum (Didelphis virginiana). The opossum shed sporocysts, which were then fed to gamma-interferon receptor knockout mice. Histopathology, immunohistochemistry, parasite isolation and molecular analysis were used to examine the pathology and associated parasites in the mice. The study suggests that the domestic cat can serve as an intermediate host to S. neurona or a S. neurona-like organsim.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Turay HO,Barr BC,Caldwell A,Branson KR,Cockrell MK,Marsh AEdoi
10.1007/s004360100503subject
Has Abstractpub_date
2002-01-01 00:00:00pages
38-43issue
1eissn
0932-0113issn
1432-1955journal_volume
88pub_type
杂志文章abstract::The experimental transmission of a recently identified new Theileria (China 1) species pathogenic for sheep and goats in northern China is described. Haemaphysalis qinghaiensis nymphs and adults developed from larvae and nymph engorged on sheep infected with Theileria sp. (China 1) were able to respectively transmit t...
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