Abstract:
:In 1997, an outbreak of alveolar echinococcosis in Japanese monkeys (Macaca fuscata) occurred in a zoo in Hokkaido, Japan. Twelve infected monkeys from a colony (n = 57) were diagnosed serologically by Western blotting, and ultrasonography showed the presence of tumor-like tissue in the livers of nine monkeys. The 12 infected monkeys have been treated with albendazole for 10 years without surgical resection. Ten of these monkeys have died so far; diagnoses were confirmed histopathologically through autopsy. Two of these monkeys are still alive. Recently, a significant difference between the two living monkeys was recognized. A difference in curative effect was demonstrated between the two living monkeys by radiography, contrast enhanced computed tomography, and contrast ultrasound. One showed metastasis to various organs, and the other appeared to be almost cured, as demonstrated by size reduction and calcification of the lesion after albendazole treatment for 10 years. This time, serological reexamination was performed to corroborate this apparent difference. The serological tests supported the preliminary imaging findings. In addition, the presence of albendazole metabolites in sera was confirmed by high-performance liquid chromatography. In this study, it was demonstrated that tests which have been used in human cases were also effective for diagnosing alveolar echinococcosis and for assessing curative effects in nonhuman primates such as M. fuscata.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Yamano K,Kanetoshi A,Goto A,Kishimoto M,Kobayashi N,Fujimoto S,Yamada Kdoi
10.1007/s00436-009-1627-2subject
Has Abstractpub_date
2009-12-01 00:00:00pages
69-74issue
1eissn
0932-0113issn
1432-1955journal_volume
106pub_type
杂志文章abstract::A small type of Cryptosporidium oocysts was isolated from a naturally infected cat and its biological nature was investigated. In cats experimentally inoculated with Cryptosporidium oocysts, long-lasting shedding of the oocysts occurred after a prepatent period of 8-10 days, and a number of peaks of oocyst count appea...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930864
更新日期:1991-01-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-007-0566-z
更新日期:2007-09-01 00:00:00
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s004360050096
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journal_title:Parasitology research
pub_type: 杂志文章
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abstract::Schizothorax o'connori and Oxygymnocypris stewartii are two endangered endemic Tibetan fishes that thrive in the Lhasa River at an average altitude over 4000 m. During artificial reproduction of endemic Tibetan fishes, the juvenile fish of S. o'connori and O. stewartii experienced mass mortality event. The causative a...
journal_title:Parasitology research
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
abstract::Toxoplasma gondii, the agent of toxoplasmosis, is an intracellular parasite that can infect a wide range of vertebrate hosts. Toxoplasmosis causes severe damage to immunocompromised hosts and its treatment is mainly based on the combination of pyrimethamine and sulfadiazine, which causes relevant side effects primaril...
journal_title:Parasitology research
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journal_title:Parasitology research
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更新日期:2017-03-01 00:00:00
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章
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更新日期:2008-10-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章,评审
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更新日期:2011-12-01 00:00:00
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journal_title:Parasitology research
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journal_title:Parasitology research
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journal_title:Parasitology research
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章
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abstract::Reports of an unusual intraerythrocytic pathogen in amphibian blood have been made for decades; these pathogens appear as membrane-bound vacuoles within erythrocytes. It is now understood that the pathogen is a Rickettsia bacteria, which are obligate intracellular parasites, and most are transmitted by arthropod vecto...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-1869-z
更新日期:2010-07-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-004-1163-z
更新日期:2004-09-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00