Abstract:
:Host association of Campylobacter jejuni was analyzed by using multilocus sequence typing data for 713 isolates from chickens and bovids (cattle and sheep). Commonly used summary measures of genotypes (sequence type and clonal complex) showed poor accuracy, but a method using the full allelic profile showed 80% accuracy in distinguishing isolates from these 2 host groups. We explored the biologic basis of more accurate results with allelic profiles. Strains isolated from specific hosts have imported a substantial number of alleles while circulating in those host species. These results imply that 1) although Campylobacter moves frequently between hosts, most transmission is within species, and 2) lineages can acquire a host signature and potentially adapt to the host through recombination. Assignment using this signature enables improved prediction of source for pathogens that undergo frequent genetic recombination.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
McCarthy ND,Colles FM,Dingle KE,Bagnall MC,Manning G,Maiden MC,Falush Ddoi
10.3201/eid1302.060620subject
Has Abstractpub_date
2007-02-01 00:00:00pages
267-72issue
2eissn
1080-6040issn
1080-6059journal_volume
13pub_type
杂志文章abstract::The 1997 Hong Kong outbreak of an avian influenzalike virus, with 18 proven human cases, many severe or fatal, highlighted the challenges of novel influenza viruses. Lessons from this episode can improve international and national planning for influenza pandemics in seven areas: expanded international commitment to fi...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid0502.990202
更新日期:1999-03-01 00:00:00
abstract::Despite a regional decline in influenza A(H1N1)pdm09 virus infections during 2013-14, cases at a Florida hospital were more severe than those during 2009-10. Examined strains had a hemagglutinin polymorphism associated with enhanced binding to lower respiratory tract receptors. Genetic changes in this virus must be mo...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2104.141375
更新日期:2015-04-01 00:00:00
abstract::Because of recent interest in bats as reservoirs of emerging diseases, we investigated the presence of viruses in Mystacina tuberculata bats in New Zealand. A novel alphacoronavirus sequence was detected in guano from roosts of M. tuberculata bats in pristine indigenous forest on a remote offshore island (Codfish Isla...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2004.131441
更新日期:2014-04-01 00:00:00
abstract::Death rates exceeded emergency thresholds at 4 sites during epidemics of Plasmodium falciparum malaria in Burundi (2000-2001) and in Ethiopia (2003-2004). Deaths likely from malaria ranged from 1,000 to 8,900, depending on site, and accounted for 52% to 78% of total deaths. Earlier detection of malaria and better case...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1301.060546
更新日期:2007-01-01 00:00:00
abstract::We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are infecting dromedaries beyond the Arabian Peninsula, where human MERS-...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2006.140299
更新日期:2014-06-01 00:00:00
abstract::The use of polymerase chain reaction-single-stranded conformational polymorphism (PCR-SSCP) to study rpoB gene mutations in rifampin-resistant (RIFr) Mycobacterium tuberculosis has yielded contradictory results. To determine the sensitivity of this method, we analyzed 35 RIFr strains and 11 rifampin-susceptible (RIFs)...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0706.010615
更新日期:2001-11-01 00:00:00
abstract::Connecticut established telephone-based gram-positive rod (GPR) reporting primarily to detect inhalational anthrax cases more quickly. From March to December 2003, annualized incidence of blood isolates was 21.3/100,000 persons; reports included 293 Corynebacterium spp., 193 Bacillus spp., 73 Clostridium spp., 26 Lact...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1109.041013
更新日期:2005-09-01 00:00:00
abstract::Serologic studies for swine influenza viruses (SIVs) in humans with occupational exposure to swine have been reported from the Americas but not from Europe. We compared levels of neutralizing antibodies against 3 influenza viruses--pandemic (H1N1) 2009, an avian-like enzootic subtype H1N1 SIV, and a 2007-08 seasonal s...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1703.100851
更新日期:2011-03-01 00:00:00
abstract::In 2004, canine influenza virus subtype H3N8 emerged in greyhounds in the United States. Subsequent serologic evidence indicated virus circulation in dog breeds other than greyhounds, but the virus had not been isolated from affected animals. In 2005, we conducted virologic investigation of 7 nongreyhound dogs that di...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1406.071270
更新日期:2008-06-01 00:00:00
abstract::We isolated Andes virus (formal name: Andes virus [ANDV], a species in the genus Hantavirus), from serum of an asymptomatic 10-year-old Chilean boy who died 6 days later of hantavirus pulmonary syndrome (HPS). The serum was obtained 12 days after his grandmother died from HPS and 2 days before he became febrile. No ha...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0807.010277
更新日期:2002-07-01 00:00:00
abstract::The mode of transmission of Helicobacter pylori infection is poorly characterized. In northern California, 2,752 household members were tested for H. pylori infection in serum or stool at a baseline visit and 3 months later. Among 1,752 person considered uninfected at baseline, 30 new infections (7 definite, 7 probabl...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1211.060086
更新日期:2006-11-01 00:00:00
abstract::An outbreak of severe acute respiratory syndrome (SARS) in humans, associated with a new coronavirus, was reported in Southeast Asia, Europe, and North America in early 2003. To address speculations that the virus originated in domesticated animals, or that domestic species were susceptible to the virus, we inoculated...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1002.030677
更新日期:2004-02-01 00:00:00
abstract::Dengue virus type 1 (DENV-1), which was responsible for the dengue fever outbreak in Yap State, Micronesia, in 2004, was isolated from serum samples of 4 dengue patients in Japan. Genome sequencing demonstrated that this virus belonged to genotype IV and had a 29-nucleotide deletion in the 3 noncoding region. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1202.050733
更新日期:2006-02-01 00:00:00
abstract::WU polyomavirus (WUPyV) was detected in a bone marrow transplant recipient with severe acute respiratory distress syndrome who died in 2001. Crystalline lattices of polyomavirus-like particles were observed in the patient's lung by electron microscopy. WUPyV was detected in the lung and other tissues by real-time quan...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2201.151384
更新日期:2016-01-01 00:00:00
abstract::Available animal and cell line models have suggested that specific therapeutics might be effective in treating Middle East respiratory syndrome (MERS). We conducted a systematic review of evidence for treatment with pharmacologic and supportive therapies. We developed a protocol and searched 5 databases for studies de...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2606.200037
更新日期:2020-06-01 00:00:00
abstract::The recently designated cyprinid herpesvirus 3 (CyHV-3) is an emerging agent that causes fatal disease in common and koi carp. Since its emergence in the late 1990s, this highly contagious pathogen has caused severe financial losses in common and koi carp culture industries worldwide. In addition to its economic role,...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1612.100593
更新日期:2010-12-01 00:00:00
abstract::A third serotype of human parechovirus (HPeV) has been recently isolated from stool specimens of a young Japanese child with transient paralysis. We report 3 additional cases of neonatal sepsis caused by HPeV-3 in the fall of 2001 in Canadian infants 7-27 days old. All children were hospitalized with high fever, eryth...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1101.040606
更新日期:2005-01-01 00:00:00
abstract::Fourteen influenza A(H7N9) viruses were isolated from poultry or the environment in live poultry markets in Guangdong Province, China during 2014-2015. Phylogenetic analysis showed that all viruses were descended from viruses of the second wave of influenza A(H7N9) virus infections during 2013. These viruses can be di...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2109.150635
更新日期:2015-09-01 00:00:00
abstract::Middle East respiratory syndrome (MERS) remains a serious international public health threat. With the goal of accelerating the development of countermeasures against MERS coronavirus (MERS-CoV), funding agencies, nongovernmental organizations, and researchers across the world assembled in Riyadh, Saudi Arabia, on Nov...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2208.160229
更新日期:2016-08-01 00:00:00
abstract::To study European bat lyssavirus (EBLV) in bat reservoirs in the Netherlands, native bats have been tested for rabies since 1984. For all collected bats, data including species, age, sex, and date and location found were recorded. A total of 1,219 serotine bats, Eptesicus serotinus, were tested, and 251 (21%) were pos...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1112.041200
更新日期:2005-12-01 00:00:00
abstract::Using data from travelers to 4 countries in the Middle East, we estimated 3,250 (95% CI 1,300-6,600) severe cases of Middle East respiratory syndrome occurred in this region during September 2012-January 2016. This number is 2.3-fold higher than the number of laboratory-confirmed cases recorded in these countries. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/2210.151121
更新日期:2016-10-01 00:00:00
abstract::Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses. In 2007 ZIKV caused an outbreak of relatively mild disease characterized by rash, arthralgia, and conjunctivitis on Yap Island in the southwestern Pacific Ocean. This was the first time that ZIKV was detect...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid1509.090442
更新日期:2009-09-01 00:00:00
abstract::In 2010, in Veneto Region, Italy, surveillance of summer fevers was conducted to promptly identify autochthonous cases of West Nile fever and increase detection of imported dengue and chikungunya in travelers. Surveillance highlighted the need to modify case definitions, train physicians, and when a case is identified...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1804.110753
更新日期:2012-04-01 00:00:00
abstract::Ross River virus (RRV), spread by Aedes and Culex mosquitoes, is the most commonly transmitted arbovirus in Australia. A serosurvey of blood donors in French Polynesia during 2011-2013 suggested that RRV circulated without being detected. We report RRV circulation in French Polynesia based on further screening of bloo...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2310.170583
更新日期:2017-10-01 00:00:00
abstract::The per capita incidence of human Lyme disease in the northeastern United States is more than twice that in the Midwest. However, the prevalence of Borrelia burgdorferi, the bacterium that causes Lyme disease, in the tick vector is nearly identical in the 2 regions. The disparity in human Lyme disease incidence may re...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1606.090329
更新日期:2010-06-01 00:00:00
abstract::We identified human bocavirus (HBoV) DNA by PCR in cerebrospinal fluid from adults and children with encephalitis in Sri Lanka. HBoV types 1, 2, and 3 were identified among these cases. Phylogenetic analysis of HBoV1 strain sequences found no subclustering with strains previously identified among encephalitis cases in...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1911.121548
更新日期:2013-11-01 00:00:00
abstract::Longitudinal surveillance of 2 live bird markets in Cambodia revealed year-round, high co-circulation of H5, H7, and H9 influenza viruses. We detected influenza A viruses in 51.3% of ducks and 39.6% of chickens, and co-infections, mainly by H5 and H9 viruses, in 0.8% of ducks and 4.5% of chickens. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2402.171360
更新日期:2018-02-01 00:00:00
abstract::The prevalence of body lice among 2,288 sheltered homeless persons in the city of Marseille during 2000-2017 was 12.2% and significantly decreased over time. We report a positive association between body lice infestations and older age, duration of stays in France for migrants, frequent consumption of alcohol, and tob...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2311.170516
更新日期:2017-11-01 00:00:00
abstract::Four persons with severe acute respiratory syndrome coronavirus 2 infection had traveled on the same flight from Boston, Massachusetts, USA, to Hong Kong, China. Their virus genetic sequences are identical, unique, and belong to a clade not previously identified in Hong Kong, which strongly suggests that the virus can...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2611.203254
更新日期:2020-11-01 00:00:00
abstract::Tropheryma whipplei endocarditis differs from classic Whipple disease, which primarily affects the gastrointestinal system. We diagnosed 28 cases of T. whipplei endocarditis in Marseille, France, and compared them with cases reported in the literature. Specimens were analyzed mostly by molecular and histologic techniq...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid1911.121356
更新日期:2013-11-01 00:00:00