Abstract:
:The use of polymerase chain reaction-single-stranded conformational polymorphism (PCR-SSCP) to study rpoB gene mutations in rifampin-resistant (RIFr) Mycobacterium tuberculosis has yielded contradictory results. To determine the sensitivity of this method, we analyzed 35 RIFr strains and 11 rifampin-susceptible (RIFs) strains, using the DNA sequencing of the core region of rpoB for comparison. Of the RIFr, 24 had a PCR-SSCP pattern identical to that of H37Rv; the other 11 had four different patterns. The 11 RIFs had PCR-SSCP patterns identical to that of H37Rv. The sensitivity of the assay was 31.4%; its specificity was 100%. We observed a strong correlation between the degree of resistance and the type of mutation.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Bobadilla-del-Valle M,Ponce-de-Leon A,Arenas-Huertero C,Vargas-Alarcon G,Kato-Maeda M,Small PM,Couary P,Ruiz-Palacios GM,Sifuentes-Osornio Jdoi
10.3201/eid0706.010615subject
Has Abstractpub_date
2001-11-01 00:00:00pages
1010-3issue
6eissn
1080-6040issn
1080-6059journal_volume
7pub_type
杂志文章abstract::Baboons on South Africa's Cape Peninsula come in frequent contact with humans. To determine potential health risks for both species, we screened 27 baboons from 5 troops for 10 infections. Most (56%) baboons had antibodies reactive or cross-reactive to human viruses. Spatial overlap between these species poses low but...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1802.111309
更新日期:2012-02-01 00:00:00
abstract::In September 2010, autochthonous transmission of chikungunya virus was recorded in southeastern France, where the Aedes albopictus mosquito vector is present. Sequence analysis of the viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the virus in Euro...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1705.101873
更新日期:2011-05-01 00:00:00
abstract::We investigated the influence of a mass poultry vaccination campaign on passive surveillance of highly pathogenic avian influenza subtype (H5N1) outbreaks among poultry in Egypt. Passive reporting dropped during the campaign, although probability of infection remained unchanged. Future poultry vaccination campaigns sh...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1812.120616
更新日期:2012-12-01 00:00:00
abstract::Outbreaks of serious infections associated with heroin use in persons who inject drugs (PWIDs) occur intermittently and require vigilance and rapid reporting of individual cases. Here, we give a firsthand account of the cases in London during an outbreak of heroin-associated anthrax during 2009-2010 in the United King...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2007.131764
更新日期:2014-07-01 00:00:00
abstract::Central venous catheters, often needed by cancer patients, can be the source of Nocardia bacteremia. We evaluated the clinical characteristics and outcomes of 17 cancer patients with Nocardia bacteremia. For 10 patients, the bacteremia was associated with the catheter; for the other 7, it was a disseminated infection....
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1709.101810
更新日期:2011-09-01 00:00:00
abstract::We analyzed 43 CTX-M-15-producing Escherichia coli isolates and 6 plasmids encoding the blaCTX-M-15 gene from Canada, India, Kuwait, France, Switzerland, Portugal, and Spain. Most isolates belonged to phylogroups B2 (50%) and D (25%). An EC-B2 strain of clonal complex sequence type (ST) 131 was detected in all countri...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1402.070350
更新日期:2008-02-01 00:00:00
abstract::We report the first known case of a device-related bloodstream infection involving Staphylococcus lugdunensis small-colony variants. Recurrent pacemaker-related bloodstream infection within a period of 10 months illustrates the poor clinical and microbiologic response even to prolonged antimicrobial drug therapy in a ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1108.041177
更新日期:2005-08-01 00:00:00
abstract::In March 2017, a patient became febrile within 4 days after visiting a rustic conference center in Austin, Texas, USA, where Austin Public Health suspected an outbreak of tickborne relapsing fever a month earlier. Evaluation of a patient blood smear and molecular diagnostic assays identified Borrelia turicatae as the ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2411.172033
更新日期:2018-11-01 00:00:00
abstract::A cross-sectional serosurvey was conducted to assess the proportion of persons exposed to hantaviruses in a virus-endemic area of the state of Minas Gerais, Brazil. Findings of this study suggested the presence of > or =1 hantaviruses circulating in this region causing hantavirus pulmonary syndrome, mild disease, or a...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1512.090229
更新日期:2009-12-01 00:00:00
abstract::Preventing emergence of new zoonotic viruses depends on understanding determinants for human risk. Nipah virus (NiV) is a lethal zoonotic pathogen that has spilled over from bats into human populations, with limited person-to-person transmission. We examined ecologic and human behavioral drivers of geographic variatio...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2309.161922
更新日期:2017-09-01 00:00:00
abstract::Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus neoformans have been increasing steadily over the past 10 years because of the onset of AIDS and the expanded use of immunosuppressive drugs. Intricate host-organism interactions make the full understanding of pathogenicity and virulen...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid0401.980109
更新日期:1998-01-01 00:00:00
abstract::Nontuberculous mycobacteria are human pathogens with increasing incidence and prevalence worldwide. Mycobacterium shimoidei is a rare cause of pulmonary disease, with only 15 cases previously reported. This series documents an additional 23 cases of M. shimoidei from Queensland, Australia, and highlights the pathogeni...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2311.170999
更新日期:2017-11-01 00:00:00
abstract::Recent outbreaks of highly pathogenic avian influenza in Asia and associated human infections have led to a heightened level of awareness and preparation for a possible influenza pandemic. Vaccination is the best option by which spread of a pandemic virus could be prevented and severity of disease reduced. Production ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid1201.051147
更新日期:2006-01-01 00:00:00
abstract::Acute flaccid myelitis (AFM) is a polio-like disease that results in paralysis in previously healthy persons. Although the definitive cause of AFM remains unconfirmed, enterovirus D68 (EV-D68) is suspected based on 2014 data demonstrating an increase in AFM cases concomitant with an EV-D68 outbreak. We examined the pr...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2509.190468
更新日期:2019-09-01 00:00:00
abstract::A retrospective investigation of skin and soft tissue infections caused by community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains among inmates in a Wisconsin correctional facility suggested a shift in MRSA genotype. Case timeline indicated a displacement of USA400 clone by USA300 clone. The U...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1209.051634
更新日期:2006-09-01 00:00:00
abstract::Conjugate vaccines have reduced the incidence of invasive disease caused by Haemophilus influenzae, type b (Hib), in industrialized countries and may be highly effective against Streptococcus pneumoniae. However, the serotype specificity of these vaccines has led to concern that their use may increase carriage of and ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0503.990304
更新日期:1999-05-01 00:00:00
abstract::Directors of all major BioSafety Level 4 (BSL-4) laboratories in the United States met in 2008 to review the current status of biocontainment laboratory operations and to discuss the potential impact of a proposed 2-person security rule on maximum-containment laboratory operations. Special attention was paid to the va...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1507.081523
更新日期:2009-07-01 00:00:00
abstract::Innovative regulatory and legislative measures to stimulate and facilitate the development of new antimicrobial drugs are needed. We discuss research approaches that can aid regulatory decision making on the treatment of resistant infections and minimization of resistance selection. We also outline current and future ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1202.050078
更新日期:2006-02-01 00:00:00
abstract::Cross-species transmission of retroviruses is common in Cameroon. To determine risk for simian T-cell lymphotropic virus (STLV) transmission from nonhuman primates to hunters, we examined 170 hunter-collected dried blood spots (DBS) from 12 species for STLV. PCR with generic tax and group-specific long terminal repeat...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1502.080584
更新日期:2009-02-01 00:00:00
abstract::To assess transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a detention facility experiencing a coronavirus disease outbreak and evaluate testing strategies, we conducted a prospective cohort investigation in a facility in Louisiana, USA. We conducted SARS-CoV-2 testing for detained perso...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2702.204158
更新日期:2021-02-01 00:00:00
abstract::From 1992 to 1999, we analyzed >2.5 million cases of influenzalike illness (ILI). Nationwide influenza epidemics generally lasted 3-4 months in winter. Kriging analysis, which illustrates geographic movement, showed that the starting areas of peak ILI activity were mostly found in western Japan. Two spreading patterns...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1010.040147
更新日期:2004-10-01 00:00:00
abstract::To determine the prevalence of helminthic infections in Pursat Province, Cambodia, we tested fecal specimens from 471 children, 10-14 years of age, in June 2007. The prevalence of infection with echinostome flukes ranged from 7.5% to 22.4% in 4 schools surveyed. Adult worms were identified as Echinostoma revolutum. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1701.100920
更新日期:2011-01-01 00:00:00
abstract::The filarial parasite Loa loa overlaps geographically with Onchocera volvulus and Wuchereria bancrofti filariae in central Africa. Accurate information regarding this overlap is critical to elimination programs targeting O. volvulus and W. bancrofti. We describe a case of loiasis in a traveler returning from Bioko Isl...
journal_title:Emerging infectious diseases
pub_type: 信件
doi:10.3201/eid2301.161427
更新日期:2017-01-01 00:00:00
abstract::To examine risk for mycosis among persons with silicosis, we examined US mortality data for 1979-2004. Persons with silicosis were more likely to die with pulmonary mycosis than were those without pneumoconiosis or those with more common pneumoconioses. Health professionals should consider enhanced risk for mycosis fo...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1602.090824
更新日期:2010-02-01 00:00:00
abstract::Staphylococcus aureus bacteremia (SAB) is a major cause of illness and death worldwide. We analyzed temporal trends of SAB incidence and death in Denmark during 2008-2015. SAB incidence increased 48%, from 20.76 to 30.37 per 100,000 person-years, during this period (p<0.001). The largest change in incidence was observ...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2505.181733
更新日期:2019-05-01 00:00:00
abstract::Rickettsia prowazekii is the causative agent of epidemic typhus and a potential bioterrorism agent. Sensitive and specific rapid assays are needed to complement existing methods of detecting this organism. We developed a real-time quantitative polymerase chain reaction assay by using a species-specific probe targeting...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1203.050888
更新日期:2006-03-01 00:00:00
abstract::We describe the detection of Bordetella holmesii as a cause of whooping cough in Spain. Prevalence was 3.9% in 2015, doubling to 8.8% in 2016. This emergence raises concern regarding the contribution of B. holmesii to the reemergence of whooping cough and the effectiveness of the pertussis vaccine. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2311.170960
更新日期:2017-11-01 00:00:00
abstract::Few data exist about perceptions regarding the etiology of foodborne illness. Among public health staff throughout Tennessee, the three pathogens most commonly believed to cause foodborne illness in the United States actually account for only 12% of disease. Fewer than 3% of respondents correctly identified the leadin...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0705.010525
更新日期:2001-09-01 00:00:00
abstract::We investigated a case of hepatitis E acquired after persons ate wild boar meat. Genotype 3 hepatitis E virus (HEV) RNA was detected in both patient serum and wild boar meat. These findings provided direct evidence of zoonotic foodborne transmission of HEV from a wild boar to a human. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1112.051041
更新日期:2005-12-01 00:00:00
abstract::Findings among a cohort of 26 patients who had hematologic malignancies and hepatitis E virus (HEV) infection support that HEV can induce chronic hepatitis. However, a 3-month course of ribavirin can induce a rapid viral clearance, reducing the risk for chronic hepatitis and enabling continuation of cytotoxic treatmen...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2108.150199
更新日期:2015-08-01 00:00:00