Abstract:
:Staphylococcus aureus bacteremia (SAB) is a major cause of illness and death worldwide. We analyzed temporal trends of SAB incidence and death in Denmark during 2008-2015. SAB incidence increased 48%, from 20.76 to 30.37 per 100,000 person-years, during this period (p<0.001). The largest change in incidence was observed for persons >80 years of age: a 90% increase in the SAB rate (p<0.001). After adjusting for demographic changes, annual rates increased 4.0% (95% CI 3.0-5.0) for persons <80 years of age, 8.4% (95% CI 7.0-11.0) for persons 80-89 years of age, and 13.0% (95% CI 9.0-17.5) for persons >90 years of age. The 30-day case-fatality rate remained stable at 24%; crude population death rates increased by 53% during 2008-2015 (p<0.001). Specific causes and mechanisms for this rapid increase in SAB incidence among the elderly population remain to be clarified.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Thorlacius-Ussing L,Sandholdt H,Larsen AR,Petersen A,Benfield Tdoi
10.3201/eid2505.181733subject
Has Abstractpub_date
2019-05-01 00:00:00issue
5eissn
1080-6040issn
1080-6059journal_volume
25pub_type
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