Vaccines for pandemic influenza.

Abstract:

:Recent outbreaks of highly pathogenic avian influenza in Asia and associated human infections have led to a heightened level of awareness and preparation for a possible influenza pandemic. Vaccination is the best option by which spread of a pandemic virus could be prevented and severity of disease reduced. Production of live attenuated and inactivated vaccine seed viruses against avian influenza viruses, which have the potential to cause pandemics, and their testing in preclinical studies and clinical trials will establish the principles and ensure manufacturing experience that will be critical in the event of the emergence of such a virus into the human population. Studies of such vaccines will also add to our understanding of the biology of avian influenza viruses and their behavior in mammalian hosts.

journal_name

Emerg Infect Dis

authors

Luke CJ,Subbarao K

doi

10.3201/eid1201.051147

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

66-72

issue

1

eissn

1080-6040

issn

1080-6059

journal_volume

12

pub_type

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