Abstract:
:Recent outbreaks of highly pathogenic avian influenza in Asia and associated human infections have led to a heightened level of awareness and preparation for a possible influenza pandemic. Vaccination is the best option by which spread of a pandemic virus could be prevented and severity of disease reduced. Production of live attenuated and inactivated vaccine seed viruses against avian influenza viruses, which have the potential to cause pandemics, and their testing in preclinical studies and clinical trials will establish the principles and ensure manufacturing experience that will be critical in the event of the emergence of such a virus into the human population. Studies of such vaccines will also add to our understanding of the biology of avian influenza viruses and their behavior in mammalian hosts.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Luke CJ,Subbarao Kdoi
10.3201/eid1201.051147subject
Has Abstractpub_date
2006-01-01 00:00:00pages
66-72issue
1eissn
1080-6040issn
1080-6059journal_volume
12pub_type
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