Extended Human-to-Human Transmission during a Monkeypox Outbreak in the Democratic Republic of the Congo.

Abstract:

:A >600% increase in monkeypox cases occurred in the Bokungu Health Zone of the Democratic Republic of the Congo during the second half of 2013; this increase prompted an outbreak investigation. A total of 104 possible cases were reported from this health zone; among 60 suspected cases that were tested, 50 (48.1%) cases were confirmed by laboratory testing, and 10 (9.6%) tested negative for monkeypox virus (MPXV) infection. The household attack rate (i.e., rate of persons living with an infected person that develop symptoms of MPXV infection) was 50%. Nine families showed >1 transmission event, and >6 transmission events occurred within this health zone. Mean incubation period was 8 days (range 4-14 days). The high attack rate and transmission observed in this study reinforce the importance of surveillance and rapid identification of monkeypox cases. Community education and training are needed to prevent transmission of MPXV infection during outbreaks.

journal_name

Emerg Infect Dis

authors

Nolen LD,Osadebe L,Katomba J,Likofata J,Mukadi D,Monroe B,Doty J,Hughes CM,Kabamba J,Malekani J,Bomponda PL,Lokota JI,Balilo MP,Likafi T,Lushima RS,Ilunga BK,Nkawa F,Pukuta E,Karhemere S,Tamfum JJ,Nguete B,Wemak

doi

10.3201/eid2206.150579

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

1014-21

issue

6

eissn

1080-6040

issn

1080-6059

journal_volume

22

pub_type

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