Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of the Congo.

Abstract:

:After an alert regarding ≈31 tuberculosis (TB) cases, 3 of which were rifampin-resistant TB cases, in Mbuji-Mayi Central Prison, Democratic Republic of the Congo, we conducted an outbreak investigation in January 2015. We analyzed sputum of presumptive TB patients by using the Xpert MTB/RIF assay. We also assessed the Mycobacterium tuberculosis isolates' drug-susceptibility patterns and risk factors for TB infection. Among a prison population of 918 inmates, 29 TB case-patients were already undergoing treatment. We found an additional 475 presumptive TB case-patients and confirmed TB in 170 of them. In March 2015, the prevalence rate of confirmed TB was 21.7% (199/918 inmates). We detected an additional 14 cases of rifampin-resistant TB and initiated treatment in all 14 of these case-patients. Overcrowded living conditions and poor nutrition appeared to be the driving factors behind the high TB incidence in this prison.

journal_name

Emerg Infect Dis

authors

Kayomo MK,Hasker E,Aloni M,Nkuku L,Kazadi M,Kabengele T,Muteteke D,Kapita F,Lufulwabo A,Mukadi YD,Muyembe-Tamfum JJ,Ieven M,de Jong BC,Boelaert M

doi

10.3201/eid2411.180769

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

2029-2035

issue

11

eissn

1080-6040

issn

1080-6059

journal_volume

24

pub_type

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