Influenza A virus (H3N8) in dogs with respiratory disease, Florida.

Abstract:

:In 2004, canine influenza virus subtype H3N8 emerged in greyhounds in the United States. Subsequent serologic evidence indicated virus circulation in dog breeds other than greyhounds, but the virus had not been isolated from affected animals. In 2005, we conducted virologic investigation of 7 nongreyhound dogs that died from respiratory disease in Florida and isolated influenza subtype H3N8 virus. Antigenic and genetic analysis of A/canine/Jacksonville/2005 (H3N8) and A/canine/Miami/2005 (H3N8) found similarity to earlier isolates from greyhounds, which indicates that canine influenza viruses are not restricted to greyhounds. The hemagglutinin contained 5 conserved amino acid differences that distinguish canine from equine lineages. The antigenic homogeneity of the canine viruses suggests that measurable antigenic drift has not yet occurred. Continued surveillance and antigenic analyses should monitor possible emergence of antigenic variants of canine influenza virus.

journal_name

Emerg Infect Dis

authors

Payungporn S,Crawford PC,Kouo TS,Chen LM,Pompey J,Castleman WL,Dubovi EJ,Katz JM,Donis RO

doi

10.3201/eid1406.071270

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

902-8

issue

6

eissn

1080-6040

issn

1080-6059

journal_volume

14

pub_type

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