Abstract:
:In 2004, canine influenza virus subtype H3N8 emerged in greyhounds in the United States. Subsequent serologic evidence indicated virus circulation in dog breeds other than greyhounds, but the virus had not been isolated from affected animals. In 2005, we conducted virologic investigation of 7 nongreyhound dogs that died from respiratory disease in Florida and isolated influenza subtype H3N8 virus. Antigenic and genetic analysis of A/canine/Jacksonville/2005 (H3N8) and A/canine/Miami/2005 (H3N8) found similarity to earlier isolates from greyhounds, which indicates that canine influenza viruses are not restricted to greyhounds. The hemagglutinin contained 5 conserved amino acid differences that distinguish canine from equine lineages. The antigenic homogeneity of the canine viruses suggests that measurable antigenic drift has not yet occurred. Continued surveillance and antigenic analyses should monitor possible emergence of antigenic variants of canine influenza virus.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Payungporn S,Crawford PC,Kouo TS,Chen LM,Pompey J,Castleman WL,Dubovi EJ,Katz JM,Donis ROdoi
10.3201/eid1406.071270subject
Has Abstractpub_date
2008-06-01 00:00:00pages
902-8issue
6eissn
1080-6040issn
1080-6059journal_volume
14pub_type
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