Immunofluorescence assay for serologic diagnosis of SARS.

Abstract:

:We evaluated an indirect immunofluorescence assay based on virus-infected cells for detecting anti-severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.

journal_name

Emerg Infect Dis

authors

Chan PK,Ng KC,Chan RC,Lam RK,Chow VC,Hui M,Wu A,Lee N,Yap FH,Cheng FW,Sung JJ,Tam JS

doi

10.3201/eid1003.030493

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

530-2

issue

3

eissn

1080-6040

issn

1080-6059

journal_volume

10

pub_type

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