Enterovirus 68 among children with severe acute respiratory infection, the Philippines.

Abstract:

:Enterovirus 68 (EV68) is a rare enterovirus associated with respiratory illness that, unlike other enteroviruses, has been identified only from respiratory specimens. We identified EV68 from respiratory specimens of children hospitalized with a diagnosis of severe pneumonia in Leyte, Republic of the Philippines. Twenty-one samples showed high similarity with EV68 by sequencing of 5' nontranslated region; 17 of these samples were confirmed as EV68 by sequencing of viral protein 1 capsid coding region. Most previously reported EV68 cases had been identified as sporadic cases. All 21 patients we identified had severe illness, and 2 died, possibly the first reported fatal cases associated with EV68 infection. Our study suggests that EV68 may be a possible causative agent of severe respiratory illnesses.

journal_name

Emerg Infect Dis

authors

Imamura T,Fuji N,Suzuki A,Tamaki R,Saito M,Aniceto R,Galang H,Sombrero L,Lupisan S,Oshitani H

doi

10.3201/eid1708.101328

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

1430-5

issue

8

eissn

1080-6040

issn

1080-6059

journal_volume

17

pub_type

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