Abstract:
:We document linezolid dependence among 5 highly linezolid-resistant (LRSE) Staphylococcus epidermidis bloodstream isolates that grew substantially faster at 32 µg/mL linezolid presence. These isolates carried the mutations T2504A and C2534T in multiple 23S rRNA copies and 2 mutations leading to relevant amino acid substitutions in L3 protein. Linezolid dependence could account for increasing LRSE emergence.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Pournaras S,Ntokou E,Zarkotou O,Ranellou K,Themeli-Digalaki K,Stathopoulos C,Tsakris Adoi
10.3201/eid1901.111527subject
Has Abstractpub_date
2013-01-01 00:00:00pages
129-32issue
1eissn
1080-6040issn
1080-6059journal_volume
19pub_type
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