Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania.

Abstract:

:We investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015-2017. We used a serologic treponemal test to detect antibodies against the bacterium. Infection was further confirmed from tissue samples of skin-ulcerated animals by 3 independent PCRs (polA, tp47, and TP_0619). Our findings indicate that T. pallidum infection is geographically widespread in Tanzania and occurs in several species (olive baboons, yellow baboons, vervet monkeys, and blue monkeys). We found the bacterium at 11 of 14 investigated geographic locations. Anogenital ulceration was the most common clinical manifestation; orofacial lesions also were observed. Molecular data show that nonhuman primates in Tanzania are most likely infected with T. pallidum subsp. pertenue-like strains, which could have implications for human yaws eradication.

journal_name

Emerg Infect Dis

authors

Chuma IS,Batamuzi EK,Collins DA,Fyumagwa RD,Hallmaier-Wacker LK,Kazwala RR,Keyyu JD,Lejora IA,Lipende IF,Lüert S,Paciência FMD,Piel A,Stewart FA,Zinner D,Roos C,Knauf S

doi

10.3201/eid2406.180037

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

1002-1009

issue

6

eissn

1080-6040

issn

1080-6059

journal_volume

24

pub_type

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