Abstract:
:We aimed to clarify changes in serotypes and genotypes mediating β-lactam and macrolide resistance in Streptococcus pneumoniae isolates from Japanese children who had invasive pneumococcal disease (IPD) after the 7-valent pneumococcal conjugate vaccine (PCV7) was introduced into Japan; 341 participating general hospitals conducted IPD surveillance during April 2010-March 2013. A total of 300 pneumococcal isolates were collected in 2010, 146 in 2011, and 156 in 2012. The proportion of vaccine serotypes in infectious isolates decreased from 73.3% to 54.8% to 14.7% during the 3 years. Among vaccine serotype strains, genotypic penicillin-resistant S. pneumoniae strains also declined each year. Among nonvaccine serotype strains, 19A, 15A, 15B, 15C, and 24 increased in 2012. Increases were noted especially in genotypic penicillin-resistant S. pneumoniae isolates of serotypes 15A and 35B, as well as macrolide resistance mediated by the erm(B) gene in 15A, 15B, 15C, and 24.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Chiba N,Morozumi M,Shouji M,Wajima T,Iwata S,Ubukata K,Invasive Pneumococcal Diseases Surveillance Study Group.doi
10.3201/eid2007.131485subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1132-9issue
7eissn
1080-6040issn
1080-6059journal_volume
20pub_type
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2303.161499
更新日期:2017-03-01 00:00:00
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doi:10.3201/eid2311.170960
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pub_type: 信件
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更新日期:2018-07-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid1509.081228
更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid2102.140961
更新日期:2015-02-01 00:00:00
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更新日期:2015-12-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.3201/eid1911.121085
更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.3201/eid1712.110896
更新日期:2011-12-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1202.050733
更新日期:2006-02-01 00:00:00
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doi:10.3201/eid2610.200319
更新日期:2020-10-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2609.200312
更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid1407.080096
更新日期:2008-07-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2609.200918
更新日期:2020-09-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 信件
doi:10.3201/eid2401.161184
更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid1708.051547
更新日期:2006-08-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid2612.200147
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2412.180214
更新日期:2018-12-01 00:00:00
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pub_type: 信件
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更新日期:2018-10-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2109.150635
更新日期:2015-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2001-09-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid1711.110721
更新日期:2011-11-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2411.172033
更新日期:2018-11-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid2207.151990
更新日期:2016-07-01 00:00:00
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pub_type: 杂志文章
doi:10.3201/eid1802.102025
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