Abstract:
:Up to 50% of persons with HIV and a diagnosis of tuberculosis (TB) in Thailand die during TB treatment. In a prospective observational study, a team of physicians ascribed the cause of death after reviewing verbal autopsies (interviews of family members about events preceding death), laboratory data, and medical records. Of 849 HIV-infected TB patients enrolled, 142 (17%) died. The cause of death was TB for 38 (27%), including 6 with multidrug-resistant TB and 20 with disseminated TB; an HIV-associated condition other than TB for 50 (35%); and a condition unrelated to TB or HIV for 22 (15%). Twenty-three patients (16%) were judged not to have had TB at all. Death from all causes except those unrelated to TB or HIV was less common in persons receiving antiretroviral therapy (ART). In addition to increasing the use of ART, death rates may be reduced through expanded use of modern TB diagnostic techniques.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Cain KP,Anekthananon T,Burapat C,Akksilp S,Mankhatitham W,Srinak C,Nateniyom S,Sattayawuthipong W,Tasaneeyapan T,Varma JKdoi
10.3201/eid1502.080942subject
Has Abstractpub_date
2009-02-01 00:00:00pages
258-64issue
2eissn
1080-6040issn
1080-6059journal_volume
15pub_type
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