Abstract:
:The per capita incidence of human Lyme disease in the northeastern United States is more than twice that in the Midwest. However, the prevalence of Borrelia burgdorferi, the bacterium that causes Lyme disease, in the tick vector is nearly identical in the 2 regions. The disparity in human Lyme disease incidence may result from a disparity in the human invasiveness of the bacteria in the Northeast and Midwest caused by fundamentally different evolutionary histories. B. burgdorferi populations in the Northeast and Midwest are geographically isolated, enabling evolutionary divergence in human invasiveness. However, we found that B. burgdorferi populations in the Northeast and Midwest shared a recent common ancestor, which suggests that substantial evolutionary divergence in human invasiveness has not occurred. We propose that differences in either animal ecology or human behavior are the root cause of the differences in human incidence between the 2 regions.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Brisson D,Vandermause MF,Meece JK,Reed KD,Dykhuizen DEdoi
10.3201/eid1606.090329subject
Has Abstractpub_date
2010-06-01 00:00:00pages
911-7issue
6eissn
1080-6040issn
1080-6059journal_volume
16pub_type
杂志文章abstract::Global expansion of antimicrobial drug-resistant Escherichia coli sequence type (ST) 131 is unrivaled among human bacteria. Understanding trends among ST131 clades will help with designing prevention strategies. We screened E. coli from blood samples (n = 1,784) obtained in Calgary, Alberta, Canada, during 2006, 2012,...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2612.201221
更新日期:2020-12-01 00:00:00
abstract::Human bocavirus (HBoV) is a widespread respiratory virus. To improve diagnostic methods, we conducted immunoglobulin (Ig) G and IgM enzyme immunoassays with recombinant virus-like particles of HBoV as antigen. Acute-phase and follow-up serum samples from 258 wheezing children and single serum samples from 115 healthy ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1509.090204
更新日期:2009-09-01 00:00:00
abstract::Severe thrombocytopenia during or after the course of Zika virus infection has been rarely reported. We report 7 cases of severe thrombocytopenia and hemorrhagic signs and symptoms in Guadeloupe after infection with this virus. Clinical course and laboratory findings strongly suggest a causal link between Zika virus i...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2304.161967
更新日期:2017-04-01 00:00:00
abstract::A third serotype of human parechovirus (HPeV) has been recently isolated from stool specimens of a young Japanese child with transient paralysis. We report 3 additional cases of neonatal sepsis caused by HPeV-3 in the fall of 2001 in Canadian infants 7-27 days old. All children were hospitalized with high fever, eryth...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1101.040606
更新日期:2005-01-01 00:00:00
abstract::Rectal lymphogranuloma venereum (LGV) has reemerged as a sexually transmitted infection among men who have sex with men (MSM), particularly those who are HIV-positive. We undertook a systematic review and meta-analysis to determine the efficacy of doxycycline (100 mg 2×/d for 21 days) for rectal LGV in MSM. Nine studi...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,meta分析,评审
doi:10.3201/eid2210.160986
更新日期:2016-10-01 00:00:00
abstract::The era of genomics (the study of genes and their function) began a scant dozen years ago with a suggestion by James Watson that the complete DNA sequence of the human genome be determined. Since that time, the human genome project has attracted a great deal of attention in the scientific world and the general media; ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0605.000508
更新日期:2000-09-01 00:00:00
abstract::[This corrects the article on p. 1690 in vol. 23, PMID: 28930024.]. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,已发布勘误
doi:10.3201/eid2402.C12402
更新日期:2018-02-01 00:00:00
abstract::We report characteristics of oseltamivir-resistant influenza A(H1N1)pdm09 viruses and patients infected with these viruses in the United States. During 2013-14, fifty-nine (1.2%) of 4,968 analyzed US influenza A(H1N1)pdm09 viruses had the H275Y oseltamivir resistance-conferring neuraminidase substitution. Our results ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2101.141006
更新日期:2015-01-01 00:00:00
abstract::Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic surveys with multiplex...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2407.171928
更新日期:2018-07-01 00:00:00
abstract::SARS coronavirus injected intratracheally into chickens, turkeys, geese, ducks, and quail, or into the allantoic sac of their embryonating eggs, failed to cause disease or replicate. This finding suggests that domestic poultry were unlikely to have been the reservoir, or associated with dissemination, of SARS coronavi...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1005.030827
更新日期:2004-05-01 00:00:00
abstract::The mode of transmission of Helicobacter pylori infection is poorly characterized. In northern California, 2,752 household members were tested for H. pylori infection in serum or stool at a baseline visit and 3 months later. Among 1,752 person considered uninfected at baseline, 30 new infections (7 definite, 7 probabl...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1211.060086
更新日期:2006-11-01 00:00:00
abstract::An outbreak of influenza A(H7N2) virus in cats in a shelter in New York, NY, USA, resulted in zoonotic transmission. Virus isolated from the infected human was closely related to virus isolated from a cat; both were related to low pathogenicity avian influenza A(H7N2) viruses detected in the United States during the e...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2312.170798
更新日期:2017-12-01 00:00:00
abstract::Powassan virus (POWV) lineage II is an emerging tickborne flavivirus with an unknown seroprevalence in humans. In a Lyme disease-endemic area, we examined the seroreactivity to POWV in 2 patient cohorts and described the clinical features of the POWV-seroreactive patients. POWV disease might be less neuroinvasive than...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2308.161971
更新日期:2017-08-01 00:00:00
abstract::Four hundred specimens were collected from pediatric patients hospitalized in Singapore; 21 of these specimens tested positive for human metapneumovirus (HMPV), with the A2 genotype predominating. A 5% infection rate was estimated, suggesting that HMPV is a significant cause of morbidity among the pediatric population...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1309.070220
更新日期:2007-09-01 00:00:00
abstract::We isolated Andes virus (formal name: Andes virus [ANDV], a species in the genus Hantavirus), from serum of an asymptomatic 10-year-old Chilean boy who died 6 days later of hantavirus pulmonary syndrome (HPS). The serum was obtained 12 days after his grandmother died from HPS and 2 days before he became febrile. No ha...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0807.010277
更新日期:2002-07-01 00:00:00
abstract::Fourteen isolations of West Nile (WN) virus were obtained from four mosquito species (Culex pipiens [5], Cx. restuans [4], Cx. salinarius [2], and Culiseta melanura [3]) in statewide surveillance conducted from June through October 2000. Most isolates were obtained from mosquitoes collected in densely populated reside...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0704.010413
更新日期:2001-07-01 00:00:00
abstract::Murine typhus was diagnosed by PCR in 50 (7%) of 756 adults with febrile illness seeking treatment at Patan Hospital in Kathmandu, Nepal. Of patients with murine typhus, 64% were women, 86% were residents of Kathmandu, and 90% were unwell during the winter. No characteristics clearly distinguished typhus patients from...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1410.080236
更新日期:2008-10-01 00:00:00
abstract::A decision analytical model was developed to investigate the cost-effectiveness of stockpiling antiviral (AV) drugs for a potential influenza pandemic in the United Kingdom and the possible role of near-patient testing in conserving AV drug stocks. Under base-case assumptions (including a fixed stockpile that was smal...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1402.070478
更新日期:2008-02-01 00:00:00
abstract::African swine fever virus p72 genotype IX, associated with outbreaks in eastern Africa, is cocirculating in the Republic of the Congo with West African genotype I. Data suggest that viruses from eastern Africa are moving into western Africa, increasing the threat of outbreaks caused by novel viruses in this region. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1708.101877
更新日期:2011-08-01 00:00:00
abstract::We conducted a retrospective study of 99 patients with methicillin-suseptible Staphylococcus aureus catheter-related bacteremia in which vancomycin MIC was determined by Etest. High vancomycin MIC (>1.5 ug/mL) was the only independent risk factor for development of complicated bacteremia caused by methicillin-suscepti...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid/1706.101037
更新日期:2011-06-01 00:00:00
abstract::We used whole-genome sequence typing (WGST) to investigate an outbreak of Sarocladium kiliense bloodstream infections (BSI) associated with receipt of contaminated antinausea medication among oncology patients in Colombia and Chile during 2013-2014. Twenty-five outbreak isolates (18 from patients and 7 from medication...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2203.151193
更新日期:2016-03-01 00:00:00
abstract::Two different West Nile virus (WNV) strains caused lethal encephalitis in a flock of geese and a goshawk in southeastern Hungary in 2003 and 2004, respectively. During the outbreak in geese, 14 confirmed human cases of WNV encephalitis and meningitis were reported in the same area. Sequencing of complete genomes of bo...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1204.051379
更新日期:2006-04-01 00:00:00
abstract::An outbreak of severe acute respiratory syndrome (SARS) in humans, associated with a new coronavirus, was reported in Southeast Asia, Europe, and North America in early 2003. To address speculations that the virus originated in domesticated animals, or that domestic species were susceptible to the virus, we inoculated...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1002.030677
更新日期:2004-02-01 00:00:00
abstract::Highland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population approximately 7,400 persons), annual household indoor residual spraying with a synthetic pyreth...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1512.090627
更新日期:2009-12-01 00:00:00
abstract::White-nose syndrome has devastated bat populations in eastern North America. In Midwestern United States, prevalence increased quickly in the first year of invasion (2012-13) but with low population declines. In the second year (2013-14), environmental contamination led to earlier infection and high population decline...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2106.150123
更新日期:2015-06-01 00:00:00
abstract::In late 2013, outbreaks of porcine epidemic diarrhea virus (PEDV) infection recurred in South Korea. Genetic and phylogenetic analyses showed that isolates from the outbreaks were most closely related to emergent US strains of PEDV. These US strain-like PEDV variants are prevalent in South Korea and responsible for re...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2007.140294
更新日期:2014-07-01 00:00:00
abstract::Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4 virus emerged in 2016 and spread to Russia, Europe, and Africa. Our analysis of viruses from domestic ducks at Tanguar haor, Bangladesh, showed genetic similarities with other viruses from wild birds in central Asia, suggesting their potential role in the genesis...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2308.170143
更新日期:2017-08-01 00:00:00
abstract::The 1997-2005 tularemia outbreak in Bulgaria affected 285 people. Ten strains were isolated from humans, a tick, a hare, and water. Amplified fragment length polymorphism typing of the present isolates and of the strain isolated in 1962 suggests that a new genetic variant caused the outbreak. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1204.050709
更新日期:2006-04-01 00:00:00
abstract::The potential threat of biological warfare with a specific agent is proportional to the susceptibility of the population to that agent. Preventing disease after exposure to a biological agent is partially a function of the immunity of the exposed individual. The only available countermeasure that can provide immediate...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid0808.010516
更新日期:2002-08-01 00:00:00
abstract::To determine the proportion of Escherichia coli O157 cases in Scotland attributable to secondary spread, we analyzed data obtained through entire-population enhanced surveillance. We identified 11% of cases as secondary. Secondary cases in single households were younger than secondary cases in outbreaks affecting >1 h...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1703.100167
更新日期:2011-03-01 00:00:00