Integrated Serologic Surveillance of Population Immunity and Disease Transmission.

Abstract:

:Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic surveys with multiplex antibody assays would create new opportunities for integrated surveillance. In this perspective, we highlight multiple areas for potential synergy where integrated surveillance could add more value to public health efforts than the current trend of independent disease monitoring through vertical programs. We describe innovations in laboratory and data science that should accelerate integration and identify remaining challenges with respect to specimen collection, testing, and analysis. Throughout, we illustrate how information generated through integrated surveillance platforms can create new opportunities to more quickly and precisely identify global health program gaps that range from undervaccination to emerging pathogens to multilayered health disparities that span diverse communicable diseases.

journal_name

Emerg Infect Dis

authors

Arnold BF,Scobie HM,Priest JW,Lammie PJ

doi

10.3201/eid2407.171928

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

1188-1194

issue

7

eissn

1080-6040

issn

1080-6059

journal_volume

24

pub_type

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