Abstract:
:Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic surveys with multiplex antibody assays would create new opportunities for integrated surveillance. In this perspective, we highlight multiple areas for potential synergy where integrated surveillance could add more value to public health efforts than the current trend of independent disease monitoring through vertical programs. We describe innovations in laboratory and data science that should accelerate integration and identify remaining challenges with respect to specimen collection, testing, and analysis. Throughout, we illustrate how information generated through integrated surveillance platforms can create new opportunities to more quickly and precisely identify global health program gaps that range from undervaccination to emerging pathogens to multilayered health disparities that span diverse communicable diseases.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Arnold BF,Scobie HM,Priest JW,Lammie PJdoi
10.3201/eid2407.171928subject
Has Abstractpub_date
2018-07-01 00:00:00pages
1188-1194issue
7eissn
1080-6040issn
1080-6059journal_volume
24pub_type
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