Cyprinid herpesvirus 3.

Abstract:

:The recently designated cyprinid herpesvirus 3 (CyHV-3) is an emerging agent that causes fatal disease in common and koi carp. Since its emergence in the late 1990s, this highly contagious pathogen has caused severe financial losses in common and koi carp culture industries worldwide. In addition to its economic role, recent studies suggest that CyHV-3 may have a role in fundamental research. CyHV-3 has the largest genome among viruses in the order Herpesvirales and serves as a model for mutagenesis of large DNA viruses. Other studies suggest that the skin of teleost fish represents an efficient portal of entry for certain viruses. The effect of temperature on viral replication suggests that the body temperature of its poikilotherm host could regulate the outcome of the infection (replicative vs. nonreplicative). Recent advances with regard to CyHV-3 provide a role for this virus in fundamental and applied research.

journal_name

Emerg Infect Dis

authors

Michel B,Fournier G,Lieffrig F,Costes B,Vanderplasschen A

doi

10.3201/eid1612.100593

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1835-43

issue

12

eissn

1080-6040

issn

1080-6059

journal_volume

16

pub_type

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