Abstract:
:The recently designated cyprinid herpesvirus 3 (CyHV-3) is an emerging agent that causes fatal disease in common and koi carp. Since its emergence in the late 1990s, this highly contagious pathogen has caused severe financial losses in common and koi carp culture industries worldwide. In addition to its economic role, recent studies suggest that CyHV-3 may have a role in fundamental research. CyHV-3 has the largest genome among viruses in the order Herpesvirales and serves as a model for mutagenesis of large DNA viruses. Other studies suggest that the skin of teleost fish represents an efficient portal of entry for certain viruses. The effect of temperature on viral replication suggests that the body temperature of its poikilotherm host could regulate the outcome of the infection (replicative vs. nonreplicative). Recent advances with regard to CyHV-3 provide a role for this virus in fundamental and applied research.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Michel B,Fournier G,Lieffrig F,Costes B,Vanderplasschen Adoi
10.3201/eid1612.100593subject
Has Abstractpub_date
2010-12-01 00:00:00pages
1835-43issue
12eissn
1080-6040issn
1080-6059journal_volume
16pub_type
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