Aripiprazole augmentation of incomplete treatment response in an adolescent male with obsessive-compulsive disorder.

abstract：BACKGROUND:Transdiagnostic cognitive-behavioral treatments for anxiety disorders have been gaining increased attention and empirical study in recent years. Despite this, research on transdiagnostic anxiety treatments has, to date, relied on open trials, or comparisons to waitlist conditions, published benchmarks, or re...

journal_title：Depression and anxiety

authors： Norton PJ,Barrera TL

更新日期：2012-10-01 00:00:00

abstract：:Serotonergic (5-hydroxytryptamine; 5-HT) mechanisms have been implicated in a number of physiological and pathophysiological processes including mood, anxiety, and cognitive functioning. Among the many 5-HT receptor subtypes, the 5-HT2A receptors (5-HT2A-R) seem to be of particular importance in mediating these effect...

journal_title：Depression and anxiety

authors： Cohen H

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:A history of past major depressive episodes (MDEs) is known to be a risk factor for future MDEs. Additional information about the relationship between past and future episodes would be useful in clinical practice, it is therefore important to fully understand the epidemiology of major depression. We asked wh...

journal_title：Depression and anxiety

authors： Bulloch A,Williams J,Lavorato D,Patten S

更新日期：2014-01-01 00:00:00

abstract：:We examined the personality characteristics of depressed patients with and without atypical depression. Of 195 depressed outpatients in a randomized treatment trial of fluoxetine or nortriptyline, 16 met DSM-IV criteria for atypical depression. We compared the personality traits and disorders in those with and without...

journal_title：Depression and anxiety

authors： Joyce PR,Mulder RT,McKenzie JM,Luty SE,Cloninger CR

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To compare the rates of low birth weight, preterm delivery and small for gestational age (SGA), in pregnancy outcomes among women who were exposed and nonexposed to antidepressants during pregnancy. METHODS:At The Motherisk Program, we analyzed pregnancy outcomes of 1,243 women in our database who took vario...

journal_title：Depression and anxiety

authors： Einarson A,Choi J,Einarson TR,Koren G

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...

journal_title：Depression and anxiety

authors： Zhang X,Liu J,Guo Y,Jiang W,Yu J

更新日期：2015-10-01 00:00:00

abstract：:The chronicity and morbidity of established post-traumatic stress disorder (PTSD) has stimulated interest in recognizing and understanding the early development of the disorder. Acute stress disorder, a new diagnosis intended to facilitate early case detection, rests on the occurrence of dissociative reactions. It rem...

journal_title：Depression and anxiety

authors： Mellman TA,David D,Bustamante V,Fins AI,Esposito K

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Despite its popularity, little is known about the measurement invariance of the Patient Health Questionnaire-9 (PHQ-9) across U.S. sociodemographic groups. Use of a screener shown not to possess measurement invariance could result in under/over-detection of depression, potentially exacerbating sociodemograph...

journal_title：Depression and anxiety

authors： Patel JS,Oh Y,Rand KL,Wu W,Cyders MA,Kroenke K,Stewart JC

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Synchronized transcranial magnetic stimulation (sTMS) is a new modality to reduce symptoms of major depressive disorder (MDD). sTMS uses rotating neodymium magnets to deliver low-field stimulation matched to the individual alpha frequency (IAF). A previous multisite study showed that sTMS significantly reduc...

journal_title：Depression and anxiety

authors： Philip NS,Leuchter AF,Cook IA,Massaro J,Goethe JW,Carpenter LL

更新日期：2019-03-01 00:00:00

abstract：:Anxiety disorders are among the most common psychiatric disorders, affecting one in four individuals over a lifetime. Although our understanding of the etiology of these disorders is incomplete, familial and genetic factors are established risk factors. However, identifying the specific casual genes has been difficult...

journal_title：Depression and anxiety

authors： Smoller JW,Block SR,Young MM

更新日期：2009-01-01 00:00:00

abstract：:Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the di...

journal_title：Depression and anxiety

authors： Picó-Pérez M,Ipser J,Taylor P,Alonso P,López-Solà C,Real E,Segalàs C,Roos A,Menchón JM,Stein DJ,Soriano-Mas C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Although evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD) were implemented starting in 2005 in the veterans health administration (VHA), the largest national healthcare system in the U.S., the rate of initiation (uptake) and prevalence of these treatments in each calendar year h...

journal_title：Depression and anxiety

authors： Maguen S,Holder N,Madden E,Li Y,Seal KH,Neylan TC,Lujan C,Patterson OV,DuVall SL,Shiner B

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...

journal_title：Depression and anxiety

authors： Gommoll C,Durgam S,Mathews M,Forero G,Nunez R,Tang X,Thase ME

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...

journal_title：Depression and anxiety

authors： Ollmann TM,Voss C,Venz J,Seidl E,Hoyer J,Kische H,Pieper L,Schiele MA,Domschke K,Beesdo-Baum K

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Although diagnostically dissociable, anxiety is strongly co-morbid with depression. To examine further the clinical symptoms of anxiety in major depressive disorder (MDD), a non-parametric item response analysis on "blinded" data from four pharmaceutical company clinical trials was performed on the Hamilton ...

journal_title：Depression and anxiety

authors： Vaccarino AL,Evans KR,Sills TL,Kalali AH

更新日期：2008-01-01 00:00:00

abstract：:Our objective was to evaluate parental risk factors for pediatric-onset panic disorder/agoraphobia (PD/AG) in offspring at high risk for PD/AG. Comparisons were made between parents with PD who had a child with PD or AG (N = 27) and parents with PD without children with PD or AG (N = 79). Comparisons were also made be...

journal_title：Depression and anxiety

authors： Biederman J,Petty C,Faraone SV,Hirshfeld-Becker DR,Henin A,Dougherty M,Lebel TJ,Pollack M,Rosenbaum JF

更新日期：2005-01-01 00:00:00

abstract：:Data from early studies of selective serotonin reuptake inhibitors have shown that these agents are effective in the treatment of social anxiety disorder (social phobia). This review highlights the outcomes of three large clinical trials of paroxetine in patients with social anxiety disorder. In two of the studies, pa...

journal_title：Depression and anxiety

authors： Lydiard RB,Bobes J

更新日期：2000-01-01 00:00:00

abstract：:There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems in depression and anxiety disorders. The majority of evidence supports underactivation of serotonergic function and complex dysregulation of noradrenergic function, most consistent with overactivation o...

journal_title：Depression and anxiety

authors： Ressler KJ,Nemeroff CB

更新日期：2000-01-01 00:00:00

abstract：:In spite of substantial advances in the treatment of major depression by pharmacotherapy and other means, a significant number of depressed patients require hospitalization. In the context of the Jerusalem Collaborative Depression Project, possible precipitants of psychiatric hospitalization were sought in a cohort of...

journal_title：Depression and anxiety

authors： Lerer B,Shapira B,Bloch M,Hanin B,Trudart T,Alexander JR,Popper M,Braun D,Segman RH,Ritsner M

更新日期：1999-01-01 00:00:00

abstract：:An impediment to progress in mood disorders research is the lack of analytically valid and qualified diagnostic and treatment biomarkers. Consistent with the National Institute of Mental Health (NIMH)'s Research Domain Criteria (RDoC) initiative, the lack of diagnostic biomarkers has precluded us from moving away from...

journal_title：Depression and anxiety

authors： Niciu MJ,Mathews DC,Nugent AC,Ionescu DF,Furey ML,Richards EM,Machado-Vieira R,Zarate CA Jr

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...

journal_title：Depression and anxiety

authors： Kun P,Han S,Chen X,Yao L

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Understanding cognitive and biological mechanisms of PTSD treatment can help refine treatments and increase rates of response. METHODS:Thirty-six veterans with PTSD were randomly assigned to receive Prolonged exposure therapy (PE) or Present-Centered therapy (PCT). We examined symptoms, trauma-related cogni...

journal_title：Depression and anxiety

authors： Rauch SA,King AP,Abelson J,Tuerk PW,Smith E,Rothbaum BO,Clifton E,Defever A,Liberzon I

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The link between systemic inflammation and depression has been deeply investigated, but relatively few studies explored symptom-specific associations, mostly focusing on common inflammatory biomarkers like C-reactive protein (CRP) levels. METHODS:We investigated associations of low-grade inflammation with d...

journal_title：Depression and anxiety

authors： Gialluisi A,Di Castelnuovo A,Bracone F,De Curtis A,Cerletti C,Donati MB,de Gaetano G,Iacoviello L

更新日期：2020-09-01 00:00:00

abstract：:The psychometric properties of the Social Phobia Anxiety Inventory (SPAI) were assessed in a sample of participants who either had a primary diagnosis of social phobia or were normal volunteers. Positive evidence was obtained on the SPAI's concurrent and predictive convergent validity: it was significantly correlated ...

journal_title：Depression and anxiety

authors： Rodebaugh TL,Chambless DL,Terrill DR,Floyd M,Uhde T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Brain-derived neurotrophic factor (BDNF) may have an important role in the pathophysiology of depression. Previous studies indicate that serum BDNF levels were lower in patients with depression and increased after treatment with antidepressants. However, results of studies on serum BDNF levels in remitted pa...

journal_title：Depression and anxiety

authors： Takebayashi N,Maeshima H,Baba H,Nakano Y,Satomura E,Kita Y,Namekawa Y,Nomoto H,Suzuki T,Arai H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Prenatal maternal depression has been associated with multiple problems in offspring involving affect, cognition, and neuroendocrine functioning. This suggests that prenatal depression influences neurodevelopment. However, the underlying neurodevelopmental mechanism remains unclear. We prospectively assessed...

journal_title：Depression and anxiety

authors： El Marroun H,Zou R,Muetzel RL,Jaddoe VW,Verhulst FC,White T,Tiemeier H

更新日期：2018-04-01 00:00:00

abstract：:The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the treatment of depressi...

journal_title：Depression and anxiety

authors： Lee S,Walker JR,Jakul L,Sexton K

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:The impact of childhood adversity persists across the life course. This study aimed to investigate the associations of childhood adversity with the course, suicidality, and treatment outcomes of depressive disorders. METHOD:A total of 919 people with depressive disorders were recruited. Childhood adversities...

journal_title：Depression and anxiety

authors： Kim SW,Kang HJ,Kim SY,Kim JM,Yoon JS,Jung SW,Lee MS,Yim HW,Jun TY

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that mindfulness may be an effective component for posttraumatic stress disorder (PTSD) treatment. Mindfulness involves practice in volitional shifting of attention from "mind wandering" to present-moment attention to sensations, and cultivating acceptance. We examined potential neural...

journal_title：Depression and anxiety

authors： King AP,Block SR,Sripada RK,Rauch S,Giardino N,Favorite T,Angstadt M,Kessler D,Welsh R,Liberzon I

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Depression and substance use disorders (SUDs) commonly co-occur, which presents diagnostic challenges in classifying independent major depressive disorder (MDD) versus substance-induced depressive disorder (SIDD). It remains unclear if distinct characteristics and/or patterns in temporal course distinguish M...

journal_title：Depression and anxiety

authors： Magidson JF,Wang S,Lejuez CW,Iza M,Blanco C

更新日期：2013-06-01 00:00:00