Preliminary estimation of rotary torque produced by proton-motive force in fully functional F0F1-ATPase.

abstract：:Nucleobindin-2 is a 420 amino acid EF-hand Ca²⁺ binding protein that can be further processed to generate an 82 amino terminal peptide termed Nesfatin-1. To examine the function of secreted Nucleobindin-2 in adipocyte differentiation, cultured 3T3-L1 cells were incubated with either 0 or 100 nM of GST, GST-Nucleobindi...

journal_title：Protein and peptide letters

authors： Tagaya Y,Osaki A,Miura A,Okada S,Ohshima K,Hashimoto K,Yamada M,Satoh T,Shimizu H,Mori M

更新日期：2012-09-01 00:00:00

abstract：:Bz(NO(2))-Orn(Boc)-OCH(2)CN was synthesized as an amino acid component with effective and successful orthogonal protection for amino acylation of 5'-O-Pivaloyl nucleosides and preparation of substrates for model ribosome reactions. The synthesis was carried out using suitable combinations of the methods of peptide syn...

journal_title：Protein and peptide letters

authors： Bayryamov SG,Vassilev NG,Petkov DD

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Nε-acetyl L-α lysine is an unusual acetylated di-amino acid synthesized and accumulated by certain halophiles under osmotic stress. Osmolytes are generally known to protect proteins and other cellular components under various stress conditions. OBJECTIVE:The structural and functional stability imparted by N...

journal_title：Protein and peptide letters

authors： Joghee NN,Jayaraman G,Selladurai M

更新日期：2020-01-01 00:00:00

abstract：:DrTI was effective against trypsin-like enzymes from A. kuehniella and C. cephalonica, however an artificial diet was insufficient to affect the survival and body weight of either insect. The inhibitor stimulated chymotrypsin-like enzymes and probably induced the synthesis of enzymes insensitive to TLCK in neonate lar...

journal_title：Protein and peptide letters

authors： Macedo ML,Pando SC,Chevreuil LR,Marangoni S

更新日期：2009-01-01 00:00:00

abstract：:Free radicals induce protein modifications, often associated to many biological phenomena. This mini-review overviews the approaches we have used to elucidate the radical-induced damages on sulfur-containing enzymes, such as ribonuclease and lysozyme, and the possible post-translational mechanism of the damage to anot...

journal_title：Protein and peptide letters

authors： Torreggiani A,Tamba M,Ferreri C

更新日期：2007-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) triggers coordinated innate and adaptive response in host cell. HCV genome and proteins of the replicating virus are recognized as non-self-antigens by host cell to activate Toll Like Receptors (TLRs). Activated TLRs ultimately express cytokines, which can clear virus either by activating inter...

journal_title：Protein and peptide letters

authors： Farooqi ZU,Tareen SH,Ahmed J,Zaidi NU

更新日期：2016-01-01 00:00:00

abstract：:The mutation, conferring streptomycin and deoxyglucose resistance on cells, had profound effect on the kinetic and thermodynamic parameters inferring thermostabilization of beta-glucosidase from mutant 51 SM(r) of Cellulomonas biazotea. Free energy of activation for substrate binding, enthalpy and entropy of activatio...

journal_title：Protein and peptide letters

authors： Rajoka MI,Durrani IS,Khalid AM

更新日期：2005-04-01 00:00:00

abstract：:Heparin is naturally occurring polysaccharides which interacts with seminal plasma proteins and regulate multiple steps in fertilization process. Qualitative and quantitative information regarding the affinity for heparin-seminal plasma proteins interactions is not generally well documented and there are no reports of...

journal_title：Protein and peptide letters

authors： Kumar V,Yadav VK,Hassan MI,Singh AK,Dey S,Singh S,Singh TP,Yadav S

更新日期：2012-08-01 00:00:00

abstract：:A halophilic nucleoside diphosphate kinase from a moderate halophile, Halomonas sp. 593 (593NDK), was found to be resistant to heat treatment, as indicated by the high level of activity recovery after heating at high temperatures. This is due to reversibility of thermal unfolding, not the high melting temperature, of ...

journal_title：Protein and peptide letters

authors： Tokunaga H,Oda Y,Yonezawa Y,Arakawa T,Tokunaga M

更新日期：2006-01-01 00:00:00

abstract：:Heat shock proteins (HSPs) consist of a large group of proteins with negligible expressions under physiological conditions. Their expressions are highly induced under stress conditions and they are ubiquitously expressed in various tissues and organs. HSPs possess chaperone functions, thus facilitating the correct fol...

journal_title：Protein and peptide letters

authors： Lu WJ,Lee NP,Fatima S,Luk JM

更新日期：2009-01-01 00:00:00

abstract：:Supramolecular self-assembled functional materials comprised of cyclic dipeptide building blocks have excellent prospects for biotechnology applications due to their exceptional structural rigidity, morphological flexibility, ease of preparation and modification. Although the pharmacological uses of many natural cycli...

journal_title：Protein and peptide letters

authors： Chen Y,Tao K,Ji W,Makam P,Rencus-Lazar S,Gazit E

更新日期：2020-01-01 00:00:00

abstract：:A significant association between increased level of blood homocysteine (hyperhomocysteinimia) and various eye pathological disorders including cataract has been reported. This metabolic byproduct is converted into a highly reactive cyclic thioester compound, homocysteine thiolactone (HCTL), which can potentially reac...

journal_title：Protein and peptide letters

authors： Hajjari S,Masoudi R,Javadi S,Hemmateenejad B,Yousefi R

更新日期：2016-01-01 00:00:00

abstract：:The formation of local structure, in short peptides has been probed by examining cleavage patterns and rates of proteolysis of designed sequences with a high tendency to form beta-hairpin structures. Three model sequences which bear fluorescence donor and acceptor groups have been investigated: [see text]. Fluorescenc...

journal_title：Protein and peptide letters

authors： Saikumari YK,Ravindra G,Balaram P

更新日期：2006-01-01 00:00:00

abstract：:Classification of newly determined protein structures is important in understanding their function and mechanism of action. Currently available methods employ a global structure alignment strategy and are computationally expensive. We propose a two-step methodology with a quick screen to significantly reduce the numbe...

journal_title：Protein and peptide letters

authors： Dalal A,Deshmukh S,Wangika PP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The O. tesota lectin PF2 is a tetrameric protein with subunits of 33 kDa that recognizes only complex carbohydrates, resistant to proteolytic enzymes and has insecticidal activity against Phaseolus beans pest. OBJECTIVE:To explore PF2 lectin features at different protein structural levels and to evaluate th...

journal_title：Protein and peptide letters

authors： Acedo-Espinoza E,Lagarda-Diaz I,Cabrera R,Guzman-Partida AM,Maldonado-Arce A,Ortega-Nieblas MM,Chan-Chan L,VázquezMoreno L

更新日期：2020-08-13 00:00:00

abstract：:G-protein betagamma dimers are prime regulators transmitting extracellular signals to wide-ranging cellular effectors including phosphoinositide 3-kinase (PI3K) isoforms beta and gamma. Recombinant Gbetagamma purified from Sf9 cells via metal-affinity and anion exchange chromatography exhibited a wortmannin-insensitiv...

journal_title：Protein and peptide letters

authors： Shymanets A,Ahmadian MR,Nürnberg B

更新日期：2009-01-01 00:00:00

abstract：:Since their recent identification, eukaryotic Hsp70 nucleotide exchange factors (NEFs) have gained increasing interest due to their engagement in vital cellular processes. Here, I summarize our current knowledge of their mechanisms of action, regulations and cellular functions as well as their relevance for human dise...

journal_title：Protein and peptide letters

authors： Kabani M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Uterine Leiomyoma is mainly widespread non-malignant tumor. Around more than 80% woman have these particular tumor among them only 30% of them are detected. Integrin-ᵦ1 is one of the up regulated biomarkers during tumorigenesis which is also associated with structural disordered. Intrinsically disordered pro...

journal_title：Protein and peptide letters

authors： Maulik U,Uversky VN,Sen S

更新日期：2018-01-01 00:00:00

abstract：:Self-Interacting Proteins (SIPs), whose two or more copies can interact with each other, have significant roles in cellular functions and evolution of Protein Interaction Networks (PINs). Knowing whether a protein can act on itself is important to understand its functions. Previous studies on SIPs have focused on thei...

journal_title：Protein and peptide letters

authors： Qu J,Zhao Y,Zhang L,Cai SB,Ming Z,Wang CC

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:The Renin-Angiotensin System (RAS) has emerged as being related to vascular disease. Recently the RAS has been associated with obesity, diabetes, and even cancer. OBJECTIVE:This review and Bioinformatics analyses focuses on the investigation of Angiotensinconverting enzymes (ACE and ACE2) as therapeutical...

journal_title：Protein and peptide letters

authors： de Carvalho Fraga CA,Farias LC,Jones KM,Batista de Paula AM,Guimaraes ALS

更新日期：2017-11-17 00:00:00

abstract：:Catalase is an enzyme that occurs in almost all aerobic organisms. Its main metabolic function is to prevent oxidative damage to tissues induced by hydrogen peroxide which is a strong oxidizing agent. Catalase is very effective in performing this task, since it has the highest turnover rate among all the enzymes. The ...

journal_title：Protein and peptide letters

authors： Seixas FA,da Silva MR,Murakami MT,Tosqui P,Colombo MF

更新日期：2011-09-01 00:00:00

abstract：:It is important to understand the conformational biases that are present in unfolded states to understand protein folding. In this context, it is surprising that even a short tripeptide like AFA samples folded/ordered conformation as demonstrated recently by NMR experiments of the peptide in aqueous solution at 280 K....

journal_title：Protein and peptide letters

authors： Patel S,Taimni R,Sasidhar YU

更新日期：2007-01-01 00:00:00

abstract：:Discriminating cell wall lytic enzymes from non lytic enzymes is a very important task for curing bacterial infections. In this paper, based on Chou's amphiphilic pseudo amino acid composition, we develop fisher-discriminant based classifier to predict cell wall lytic enzymes. Experiments show that 66.7% sensitivity w...

journal_title：Protein and peptide letters

authors： Ding H,Luo L,Lin H

更新日期：2009-01-01 00:00:00

abstract：:Migraine is a common neurologic condition marked by recurrent episodes of headache. Its pathophysiology is highly complex involving neuronal, inflammatory and vascular mechanisms. The Renin-Angiotensin System (RAS) can modulate all these mechanism, being a potential pharmacological target for migraine treatment. We ca...

journal_title：Protein and peptide letters

authors： Sassi KLM,Martins LB,de Miranda AS,Teixeira AL

更新日期：2020-01-01 00:00:00

abstract：:Like those in mammals, heterotrimeric G protein complexes have been implicated in signal transduction pathways in plants; however, the subunits themselves have not been isolated. In this study, the rice heterotrimeric G protein subunits α (Gα) and β (Gβ) were purified by affinity chromatography using anti-Gα and -Gβ a...

journal_title：Protein and peptide letters

authors： Abe Y,Matsusita K,Komatsu S,Iwasaki Y

更新日期：2012-03-01 00:00:00

abstract：:PD-L1 is a highly glycosylated type 1 ribosome inactivating protein, from Phytolacca dioica leaves, with the peculiarity to act also as a DNase. PD-L1 has been successfully crystallized using vapour diffusion and seeding techniques. Crystals belong to the monoclinic C2 space group, with unit cell dimensions a=161.01, ...

journal_title：Protein and peptide letters

authors： Ruggiero A,Chambery A,Di Maro A,Mastroianni A,Parente A,Berisio R

更新日期：2007-01-01 00:00:00

abstract：:Natural, synthetic and analogues of peptides have shown prospects for application in cancer chemotherapy. Notably, some food protein-derived peptides are known to possess anticancer activities in cultured cancer cells, and also in animal cancer models via different mechanisms including induction of apoptosis, cell cyc...

journal_title：Protein and peptide letters

authors： Rajendran SR,Ejike CE,Gong M,Hannah W,Udenigwe CC

更新日期：2017-01-01 00:00:00

abstract：:The study of rat proteins is an indispensable task in experimental medicine and drug development. The function of a rat protein is closely related to its subcellular location. Based on the above concept, we construct the benchmark rat proteins dataset and develop a combined approach for predicting the subcellular loca...

journal_title：Protein and peptide letters

authors： Shi R,Xu C

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Unstructured regions in proteins can vary from several amino acid residues to a completely disordered sequence. Since such regions play an important role in the protein functioning, much attention is being paid to their prediction. Special different programs are available for this purpose; however, predictio...

journal_title：Protein and peptide letters

authors： Deryusheva E,Machulin A,Nemashkalova E,Glyakina A,Galzitskaya O

更新日期：2018-01-01 00:00:00

abstract：:We here describe a new strategy for the delivery of oligonucleotides to cells that is based on the use of a short peptide containing three functional units: a membrane-penetrating segment, a DNA-binding domain and a cell-localization sequence. The designed vector binds strongly to oligonucleotides and has membrane-per...

journal_title：Protein and peptide letters

authors： Smith J,Guidry J,Wittung-Stafshede P

更新日期：2003-02-01 00:00:00