Prediction of cell wall lytic enzymes using Chou's amphiphilic pseudo amino acid composition.

Abstract:

:Discriminating cell wall lytic enzymes from non lytic enzymes is a very important task for curing bacterial infections. In this paper, based on Chou's amphiphilic pseudo amino acid composition, we develop fisher-discriminant based classifier to predict cell wall lytic enzymes. Experiments show that 66.7% sensitivity with 88.6% specificity is obtained. The method is further able to predict endolysin and autolysin with an overall accuracy of 92.9%. Results demonstrated that our method can provide highly useful information for further bacterial control research.

journal_name

Protein Pept Lett

authors

Ding H,Luo L,Lin H

doi

10.2174/092986609787848045

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

351-5

issue

4

eissn

0929-8665

issn

1875-5305

journal_volume

16

pub_type

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