Abstract:
:To feed an estimated world population of 8.9 billion by 2050, strategies for increasing grain production must be developed. Several agronomically important traits for increasing yield, such as plant height, grain number, and leaf erectness, have recently been characterized in rice (Oryza sativa L.). These traits are regulated primarily by three phytohormones: gibberellins, cytokinins, and brassinosteroids. The control of biosynthesis and degradation of these key phytohormones is discussed in terms of its importance for normal plant growth. Genes involved in the biosynthesis and regulation of these phytohormones can be used to develop effective strategies to increase grain yield. Genetic manipulation of phytohormone-related gene expression is thus a practical strategy to generate high-yielding transgenic plants through the modification of levels and profile of endogenous phytohormones.
journal_name
Transgenic Resjournal_title
Transgenic researchauthors
Sakamoto Tdoi
10.1007/s11248-006-0024-1subject
Has Abstractpub_date
2006-08-01 00:00:00pages
399-404issue
4eissn
0962-8819issn
1573-9368journal_volume
15pub_type
杂志文章,评审abstract::It is commonly held that confined field trials (CFTs) used to evaluate the potential adverse environmental impacts of a genetically engineered (GE) plant should be conducted in each country where cultivation is intended, even when relevant and potentially sufficient data are already available from studies conducted el...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-014-9785-0
更新日期:2014-12-01 00:00:00
abstract::Wheat and barley are the major temperate cereals, being used for food, feed and industrial raw material. However, in all cases the quality may be limited by the amount, composition and properties of the grain storage proteins. We describe how a combination of biochemical and molecular studies has led to an understandi...
journal_title:Transgenic research
pub_type: 杂志文章,评审
doi:10.1007/BF01976021
更新日期:1994-01-01 00:00:00
abstract::We wish to construct a mouse model for the human inherited disease cystic fibrosis. We describe here the successful targeting in embryonal stem cells of the murine homologue (Cftr) of the cystic fibrosis transmembrane conductance regulator gene, as the first critical step towards this end. The targeting event precisel...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/BF02513027
更新日期:1992-03-01 00:00:00
abstract::The spermatogonial transplantation system was applied to evaluate stem cell kinetics and niche quality and to produce gene-modified animals using the stem cells after homologous recombination-based selection. This study was designed to determine whether the transplanted spermatogonia were able to proliferate and diffe...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-008-9219-y
更新日期:2009-02-01 00:00:00
abstract::The activated cannabinoid receptor 1 (CB1R) is exclusively responsible for food intake and weight gain and regulates several pathological features associated with obesity in mammals. However, the precise role of CB1R in non-mammalian model systems is poorly understood. To investigate the functions of CB1R in zebrafish...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-012-9685-0
更新日期:2013-08-01 00:00:00
abstract::Over the past 15 years researchers have generated stable lines of several species of transgenic fish important for aquaculture. 'All-fish' growth hormone (GH) gene constructs and antifreeze protein (AFP) genes have been successfully introduced into the fish genome resulting in a significant acceleration of growth rate...
journal_title:Transgenic research
pub_type: 杂志文章,评审
doi:10.1023/a:1024267416522
更新日期:2003-08-01 00:00:00
abstract::The E8 promoter, a tomato fruit-ripening-specific promoter, and the CaMV 35S promoter, a constitutive promoter, were used to express the miraculin gene encoding the taste-modifying protein in tomato. The accumulation of miraculin protein and mRNA was compared among transgenic tomatoes expressing the miraculin gene dri...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-011-9495-9
更新日期:2011-12-01 00:00:00
abstract::The bacterial gene chloramphenicol acetyltransferase (CAT) is a widely used reporter in both in-vitro and in-vivo studies of genetic regulation. We have recently generated novel rat transgenic lines carrying an arylalkylamine N-acetyltransferase (AA-NAT) promoter-reporter construct in which CAT (with associated SV40 s...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1023/a:1008928121846
更新日期:2000-02-01 00:00:00
abstract::In addition to its well-recognized antimicrobial properties, lysozyme can also modulate the inflammatory response. This ability may be particularly important in the gastrointestinal tract where inappropriate inflammatory reactions can damage the intestinal epithelium, leading to significant health problems. The consum...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-011-9489-7
更新日期:2011-12-01 00:00:00
abstract::We previously demonstrated a case of silencing in transgenic plants expressing T7 RNA polymerase in which expression of a reporter gene placed under the control of the T7 promoter was silenced. Here we demonstrate that endogenous genes can be silenced by the same system. The T7-driven silencing system does not conform...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-007-9146-3
更新日期:2008-08-01 00:00:00
abstract::Supv3L1 is an evolutionarily conserved helicase that plays a critical role in the mitochondrial RNA surveillance and degradation machinery. Conditional ablation of Supv3L1 in adult mice leads to premature aging phenotypes including loss of muscle mass and adipose tissue and severe skin abnormalities. To get insights i...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-009-9346-0
更新日期:2010-08-01 00:00:00
abstract::A chimeric Bacillus thuringiensis toxin (Bt) gene, cry2AX1was cloned in a bi-selectable marker free binary vector construct. The cry2AX1 gene, driven by the Chrysanthemum rbcS1 promoter, was introduced into JK1044R, the restorer line (Oryza sativa L. ssp. Indica) of a notified commercially grown rice hybrid in India, ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-016-9954-4
更新日期:2016-10-01 00:00:00
abstract::There has been considerable interest in pursuing phospholamban as a putative therapeutic target for overcoming depressed calcium handling in human heart failure. Studies predominantly done in mice have shown that phospholamban is a key regulator of sarcoplasmic reticulum calcium cycling and cardiac function. However, ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-007-9139-2
更新日期:2008-04-01 00:00:00
abstract::Rust fungi of the order Pucciniales are destructive pathogens of wheat worldwide. Leaf rust caused by the obligate, biotrophic basidiomycete fungus Puccinia triticina (Pt) is an economically important disease capable of causing up to 50 % yield losses. Historically, resistant wheat cultivars have been used to control ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-016-9978-9
更新日期:2017-02-01 00:00:00
abstract::Genomic DNA blot hybridization is traditionally used to demonstrate that, via genetic transformation, foreign genes are integrated into host genomes. However, in large genome species, such as Allium cepa L., the use of genomic DNA blot hybridization is pushed towards its limits, because a considerable quantity of DNA ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1023/a:1016633410041
更新日期:2001-06-01 00:00:00
abstract::Gonadal effects of the Denys-Drash syndrome (DDS) mutation Wt1(tmT396 )were examined in chimaeric and heterozygous mice. Since the only heterozygote was 41,XXY, Sertoli cell function was assessed by comparison with age-matched control XXY testes. Control XXY Sertoli cells showed immuno-expression of WT1 and androgen r...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-005-7216-y
更新日期:2005-10-01 00:00:00
abstract::Watermelon, an important fruit crop worldwide, is prone to attack by several viruses that often results in destructive yield loss. To develop a transgenic watermelon resistant to multiple virus infection, a single chimeric transgene comprising a silencer DNA from the partial N gene of Watermelon silver mottle virus (W...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-011-9585-8
更新日期:2012-10-01 00:00:00
abstract::Tritrophic interactions between transgenic potato expressing the insecticidal lectin from snowdrop (Galanthus nivalis agglutinin; GNA), an aphid pest, Myzus persicae (Sulz.), and a beneficial predator, the 2-spot ladybird (Adalia bipunctata L.) were investigated. Clonal plants expressing GNA at 0.1-0.2% total soluble ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1023/a:1022904805028
更新日期:2003-04-01 00:00:00
abstract::Powdery mildew (PM) is one of the major plant pathogens. The conventional method of PM control includes frequent use of sulfur-based fungicides adding to production costs and potential harm to the environment. PM remains a major scourge for Rosaceae crops where breeding approaches mainly resort to gene-for-gene resist...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-013-9715-6
更新日期:2013-12-01 00:00:00
abstract::Competition between humans and livestock for cereal and legume grains makes it challenging to provide economical feeds to livestock animals. Recent increases in corn and soybean prices have had a significant impact on the cost of feed for pig producers. The utilization of byproducts and alternative ingredients in pig ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-014-9817-9
更新日期:2015-02-01 00:00:00
abstract::The silk gland of silkworm Bombyx mori, is one of the most important organs that has been fully studied and utilized so far. It contributes finest silk fibers to humankind. The silk gland has excellent ability of synthesizing silk proteins and is a kind tool to produce some useful recombinant proteins, which can be wi...
journal_title:Transgenic research
pub_type: 杂志文章,评审
doi:10.1007/s11248-014-9826-8
更新日期:2014-10-01 00:00:00
abstract::Multiple infections of Sweet potato feathery mottle virus (SPFMV), Sweet potato chlorotic stunt virus (SPCSV), Sweet potato virus G (SPVG) and Sweet potato mild mottle virus (SPMMV) cause a devastating synergistic disease complex of sweet potato (Ipomoea batatas Lam.) in KwaZulu-Natal, South Africa. In order to addres...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-013-9759-7
更新日期:2014-04-01 00:00:00
abstract::The mouse artificial chromosome (MAC) has several advantages as a gene delivery vector, including stable episomal maintenance of the exogenous genetic material and the ability to carry large and/or multiple gene inserts including their regulatory elements. Previously, a MAC containing multi-integration site (MI-MAC) w...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-015-9884-6
更新日期:2015-08-01 00:00:00
abstract::Matrix attachment regions (MARs) are DNA elements that can increase and stabilize transgene expression. We investigated the effect of the RB7 MAR on transgenic virus resistance. Constructs for resistance to tomato spotted wilt virus (TSWV) with and without flanking RB7 MARs were used to transform tobacco and produce h...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-004-5413-8
更新日期:2005-04-01 00:00:00
abstract::Alpha1 tubulin gene expression is induced in the developing and regenerating CNS of vertebrates. Therefore, alpha1 tubulin gene expression may serve as a good probe for mechanisms underlying CNS development and regeneration. One approach to identify these mechanisms is to work backwards from the genome. This requires ...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1023/a:1008998832552
更新日期:2001-01-01 00:00:00
abstract::Cre/loxP recombination is a powerful strategy widely used for in vivo conditional gene targeting. This technique has made possible many important discoveries of gene function in normal and disease biology. However, due to the transgenic nature of most Cre mouse strains undesired phenotypes occasionally occur in Cre mi...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-014-9828-6
更新日期:2015-02-01 00:00:00
abstract::With the potential advent of genetically modified herbicide-resistant (GMHR) crops in the European Union, changes in patterns of herbicide use are predicted. Broad-spectrum, non-selective herbicides used with GMHR crops are expected to substitute for a set of currently used herbicides, which might alter the agro-envir...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-008-9181-8
更新日期:2008-12-01 00:00:00
abstract::Plant transformation, via Agrobacterium tumefaciens, is usually performed with binary vectors. Most of the available binary vectors contain within the T-DNA (which is transferred to the plant genome) components not required for the intended modification. These additional sequences may cause potential risks during fiel...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/BF01974093
更新日期:1994-03-01 00:00:00
abstract::Camelina (Camelina sativa (L.) Crantz) is a re-emergent oilseed crop that is also becoming important as a model for applied projects based on studies in Arabidopsis thaliana, since the two species are closely related members of the tribe Camelineae of the Brassicaeae. Since camelina can be transformed genetically by f...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/s11248-013-9722-7
更新日期:2014-02-01 00:00:00
abstract::In the fowl the primordial germ cells accumulate in the germinal crescent to the anterior of the two-day embryo. A simple ballistic device has been used to fire tungsten particles (mean diameter 1.5 microns) into this region. By coating these projectiles with vector DNA it is possible to transfect these cells. Hatchli...
journal_title:Transgenic research
pub_type: 杂志文章
doi:10.1007/BF01976498
更新日期:1995-01-01 00:00:00