Gender differences in neurological disease: role of estrogens and cytokines.

abstract：:Variants of growth hormone (GH) are present in most vertebrates. Chicken GH (cGH) undergoes posttranslational modifications that contribute to its structural diversity. Although the 22-kDa form of GH is the most abundant, some other variants have discrete bioactivities that may not be shared by others. The proportion ...

journal_title：Endocrine

authors： Martínez-Coria H,López-Rosales LJ,Carranza M,Berumen L,Luna M,Arámburo C

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:We retrospectively evaluated all patients with pituitary tumours treated in our department from 1/1/1997 to 01/11/2014. PATIENTS AND METHODS:Two hundred and fifteen patients (124 females, 91 males, mean age 50.9 years) were treated because of pituitary tumours. All patients underwent basal hormonal analys...

journal_title：Endocrine

authors： Askitis D,Tsitlakidis D,Müller N,Waschke A,Wolf G,Müller UA,Kloos C

更新日期：2018-05-01 00:00:00

abstract：:Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are synthesized and released from adrenal cells. Therefore, the effects of TNF-alpha and IL-6 on cortisol release from bovine zona fasciculata (ZF) cells were investigated. IL-6 (10-1000 pg/mL) significantly increased basal and adrenocorticotropic hormon...

journal_title：Endocrine

authors： Barney M,Call GB,McIlmoil CJ,Husein OF,Adams A,Balls AG,Oliveira GK,Miner EC,Richards TA,Crawford BK,Heckmann RA,Bell JD,Judd AM

更新日期：2000-12-01 00:00:00

abstract：:Mammary cell mitogenic responsiveness was evaluated with an established nontransformed caprine mammary epithelial cell line (CMEC). As expected, the cells responded to insulin-like growth factor 1 (IGF-1), insulin, and hydrocortisone with an increased number of cells after 3 and 5 d in culture. In combination, insulin...

journal_title：Endocrine

authors： Pantschenko AG,Yang TJ

更新日期：1999-04-01 00:00:00

abstract：PURPOSE:Risk of cardiovascular disease (CVD) is increased in Graves' disease (GD). CVD is predicted by increased pulse wave velocity (PWV) and blood pressure (BP). GD and these risk factors are all associated with lower levels of vitamin D. We aimed to assess the effect of supplemental vitamin D on PWV and BP in GD. M...

journal_title：Endocrine

authors： Grove-Laugesen D,Malmstroem S,Ebbehoj E,Riis AL,Watt T,Hansen KW,Rejnmark L

更新日期：2019-11-01 00:00:00

abstract：:Testosterone deficiency is commonly associated with obesity, metabolic syndrome, type 2 diabetes and their clinical consequences-hepatic steatosis and atherosclerosis. The testicular feminised mouse (non-functional androgen receptor and low testosterone) develops fatty liver and aortic lipid streaks on a high-fat diet...

journal_title：Endocrine

authors： Kelly DM,Akhtar S,Sellers DJ,Muraleedharan V,Channer KS,Jones TH

更新日期：2016-11-01 00:00:00

abstract：:Vertebral fractures are an emerging complication of acromegaly but their prediction is still difficult occurring even in patients with normal bone mineral density. In this study we evaluated the ability of high-resolution cone-beam computed tomography to provide information on skeletal abnormalities associated with ve...

journal_title：Endocrine

authors： Maffezzoni F,Maddalo M,Frara S,Mezzone M,Zorza I,Baruffaldi F,Doglietto F,Mazziotti G,Maroldi R,Giustina A

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:A retrospective analysis was carried out from patients and controls during the past 5 years from a series of studies investigating endothelial microparticles (MP). METHODS:In total, 319 samples from 207 individuals were included in this analysis, from patients with type 2 diabetes (T2D, n = 105), women with...

journal_title：Endocrine

authors： Al-Qaissi A,Alqarni S,Javed Z,Atkin SL,Sathyapalan T,Vince RV,Madden LA

更新日期：2019-11-01 00:00:00

abstract：:The objectives of this study were to analyse the results of surgical treatment of multinodular goiter (MG) in a population with under 30 yr of age; (2) to determine the incidence and evolution of related thyroid carcinomas; and (3) to evaluate the rate of relapse. Eighty-one patients operated for MG and under 30 yr of...

journal_title：Endocrine

authors： Ríos A,Rodríguez JM,Galindo PJ,Montoya MJ,Canteras M,Parrilla P

更新日期：2005-08-01 00:00:00

abstract：:Fibromyalgia (FM) is a disease entity consisting of a heterogeneous cluster of symptoms that has thus far eluded identification of a causative etiology. The disease onset appears to follow physiological and/or psychological stressors and involves a subset of symptoms that are consistent with varied disorders found in ...

journal_title：Endocrine

authors： Shuer ML

更新日期：2003-10-01 00:00:00

abstract：:Stimulation of dopamine D2 receptors inhibits melanotrope pro-opiomelanocortin (POMC) biosynthesis and alpha-melanocyte-stimulating hormone (MSH) secretion. These effects are mediated by G-protein alpha i- and alpha o-subunits and are reversed by stimulating receptors linked to activation of G alpha s protein. Melanot...

journal_title：Endocrine

authors： Sands SA,Dickerson DS,Morris SJ,Chronwall BM

更新日期：1997-06-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) acts as a nutrient-dependent insulin-releasing agent, and its insulinotropic action is enhanced by nutrient secretagogues, such as the dimethyl ester of succinic acid (SAD). In the present study, a primed constant infusion of SAD (0.5 micromol followed by 0.25 micromol/min both per g of...

journal_title：Endocrine

authors： Cancelas J,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：2001-08-01 00:00:00

abstract：:In this study, we investigated gingival enlargement in patients with acromegaly as a component of the disease. Eleven patients (5 males, 6 females) were evaluated. Diagnosis was confirmed with typical clinical features and laboratory. Oral examinations were carried out by the same periodontist. During the examination,...

journal_title：Endocrine

authors： Capoglu I,Yilmaz AB,Unüvar N,Orbak R,Aksoy H,Yesilyurt H

更新日期：2002-08-01 00:00:00

abstract：:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are relatively rare and heterogenous malignancies. Recent advances in histopathological classification according to the anatomical site of origin, proliferation rate, and extend of the disease have created a valid and powerful tool for the prognostic stratificati...

journal_title：Endocrine

authors： Alexandraki KI,Kaltsas G

更新日期：2012-02-01 00:00:00

abstract：:Studies designed to evaluate the short-term effects of incretin-related drugs in subjects with cardiac disease are still preliminary. In patients with heart failure, two of five studies showed that glucagon-like peptide-1 (GLP-1) infusion was associated with an absolute increase in left ventricular ejection fraction (...

journal_title：Endocrine

authors： Mikhail N

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:The influence of the dipeptidyl peptidase-IV inhibitor, gemigliptin alone or in combination with metformin on survival, proliferation, and migration of thyroid carcinoma cells was investigated. METHODS:SW1736 and TPC-1 human thyroid carcinoma cells were used. RESULTS:Gemigliptin and metformin caused cell deat...

journal_title：Endocrine

authors： Kim SH,Kang JG,Kim CS,Ihm SH,Choi MG,Yoo HJ,Lee SJ

更新日期：2018-02-01 00:00:00

abstract：:To determine whether the administration of small amounts of glucose through an oral spray device (GSD) facilitates weight loss in overweight/obese subjects involved in a lifestyle modification programme. We randomly assigned 56 overweight/obese subjects to either the treatment group (n = 32) or the control group (n = ...

journal_title：Endocrine

authors： Khazrai YM,Maddaloni E,Altomare M,Cacciapaglia F,Pozzilli P

更新日期：2014-03-01 00:00:00

abstract：:The Metastatic progression of solid tumors, such as thyroid cancer is a complex process which involves various factors. Current understanding on the role of epithelial-mesenchymal transition (EMT) in thyroid carcinomas suggests that EMT is implicated in the progression from follicular thyroid cancer (FTC) and papillar...

journal_title：Endocrine

authors： Shakib H,Rajabi S,Dehghan MH,Mashayekhi FJ,Safari-Alighiarloo N,Hedayati M

更新日期：2019-12-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is linked to increased risk of insulin resistance and diabetes mellitus in patients' later life. The aim of this study was to investigate uptake of deoxy-D-glucose by peripheral blood lymphocytes of PCOS patients with normal fasting plasma glucose and normal glucose tolerance test. The...

journal_title：Endocrine

authors： Oleszczak B,Szablewski L,Pliszka M,Głuszak O,Stopińska-Głuszak U

更新日期：2014-11-01 00:00:00

abstract：:The aim of this study was to evaluate atrial electromechanical delay (EMD), P wave dispersion (Pwd), and left atrial (LA) mechanical functions in patients with active acromegaly. Twenty-three patients with active acromegaly and 27 age- and sex-matched controls were included in this study. All atrial electromechanical ...

journal_title：Endocrine

authors： Ilter A,Kırış A,Kaplan Ş,Kutlu M,Şahin M,Erem C,Civan N,Kangül F

更新日期：2015-03-01 00:00:00

abstract：:Quality of life (QoL) is an important aspect that reflects the way people feel and function. The assessment of QoL quality of life is an essential tool for estimating the efficacy of any therapy in different pathophysiological conditions. In normal, healthy women, the perception of QoL can be significantly modified du...

journal_title：Endocrine

authors： Gambacciani M

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To describe sex-related differences in self-care; to identify determinants of self-care according to sex, and to investigate how sex interacts with the effect of clinical and socio-demographic variables on self-care in adults with Type 2 Diabetes Mellitus (T2DM). METHODS:Cross-sectional multicentre study with ...

journal_title：Endocrine

authors： Caruso R,Rebora P,Luciani M,Di Mauro S,Ausili D

更新日期：2020-02-01 00:00:00

abstract：:Although ghrelin in cord blood has been associated to birth weight, its role in fetal and postnatal growth has not been elucidated. The aim of this study was to analyze total ghrelin, acyl ghrelin (AG), and des-acyl ghrelin (DAG) in cord blood of newborns with idiopathic birth weight alterations, and to evaluate prote...

journal_title：Endocrine

authors： González-Domínguez MI,Lazo-de-la-Vega-Monroy ML,Zaina S,Sabanero M,Daza-Benítez L,Malacara JM,Barbosa-Sabanero G

更新日期：2016-07-01 00:00:00

abstract：:Initiation and maintenance of labor in humans is associated with an increase in prostaglandin synthesis by intrauterine tissues. The objective of the present study was to characterize the distribution of membrane-bound PGES (mPGES) protein and mPGES mRNA in human placenta, fetal membranes, and decidua at term and to d...

journal_title：Endocrine

authors： Alfaidy N,Sun M,Challis JR,Gibb W

更新日期：2003-04-01 00:00:00

abstract：:Several studies have demonstrated an imbalance between free radicals and the antioxidative system in individuals with thyroid dysfunction. However, oxidative stress has not been evaluated in patients with thyroidectomy and thyroparathyroidectomy, who are under replacement therapy. The objective of this study was to ev...

journal_title：Endocrine

authors： Kaçmaz M,Atmaca M,Arslan A,Demir H,Özbay MF

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Bisphenol-A (BPA) is an endocrine-disrupting chemical that may affect the hormones and their receptors. The aim of this study is to determine whether BPA has an effect on the development of nonfunctional adrenal incidentaloma (NFAI). METHODS:Fifty patients who were admitted to endocrinology outpatient clinics ...

journal_title：Endocrine

authors： Eker F,Gungunes A,Durmaz S,Kisa U,Celik ZR

更新日期：2020-09-23 00:00:00

abstract：PURPOSE:Fatty acid binding protein 4 (FABP4) has been demonstrated to be secreted from adipocytes in an unconventional pathway associated with lipolysis. Circulating FABP4 is elevated in metabolic disorders and has been shown to affect various peripheral cells such as pancreatic β-cells, hepatocytes and macrophages, bu...

journal_title：Endocrine

authors： Dou HX,Wang T,Su HX,Gao DD,Xu YC,Li YX,Wang HY

更新日期：2020-03-01 00:00:00

abstract：:Detection of connexin (Cx) proteins has been used as an indicator of the presence of structural and functional gap junctions in tissues. To examine the role of gap junctions during follicular growth and atresia, the presence of three major connexins, Cx43, Cx32, and Cx26, was evaluated in bovine ovaries by using immun...

journal_title：Endocrine

authors： Johnson ML,Redmer DA,Reynolds LP,Grazul-Bilska AT

更新日期：1999-02-01 00:00:00

abstract：:The secreted hepatokine fetuin-A emerges as an independent predictor of type 2 diabetes in adulthood. The overall aims of this study were: (1) to investigate the associations of fetuin-A with adiposity and insulin resistance, as well as its relationship with adipokines, in prepubertal children, and, (2) to evaluate wh...

journal_title：Endocrine

authors： Murdolo G,Tortoioli C,Celi F,Bini V,Papi F,Brozzetti A,Falorni A

更新日期：2017-05-01 00:00:00

abstract：:The thyrotropin receptor is of fundamental importance to normal thyroid function and is considered to be the predominant antigen affected by the autoantibodies of Graves' autoimmune hyperthyroidism. The identification of the epitopes on the receptor to which the autoantibodies bind or the mechanism by which the autoan...

journal_title：Endocrine

authors： Hunt N,Willey KP,Abend N,Balvers M,Jähner D,Northemann W,Ivell R

更新日期：1995-03-01 00:00:00