Fibromyalgia: symptom constellation and potential therapeutic options.

abstract：:To explore the regulation of follistatin gene expression, porcine granulosa cells were incubated with the translational inhibitor, cycloheximide (CHX), for periods from 6-24 h. This resulted in a 3 to 10-fold increase in follistatin mRNA accumulation compared to vehicle treated control cultures. At 20 h, CHX augmented...

journal_title：Endocrine

authors： Lindsell CE,Misra V,Murphy BD

更新日期：1995-08-01 00:00:00

abstract：:The present study investigates the effects of functional sensorial denervation, induced by administering capsaicin to hemiovariectomized adult female rats in each day of the estrus cycle, on ovulation and serum concentrations of estrogen and progesterone. The results indicate that the establishment of compensatory ova...

journal_title：Endocrine

authors： Trujillo A,Morales L,Vargas X,Alba L,Domínguez R

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To evaluate whether losartan is able to induce beige adipocytes formation, focusing on the thermogenic gene expression and adipocyte remodeling in the subcutaneous white adipose tissue of diet-induced obese mice. METHODS:Male C57BL/6 mice received a control diet (10% energy as lipids) or a high-fat diet (50% e...

journal_title：Endocrine

authors： Graus-Nunes F,Rachid TL,de Oliveira Santos F,Barbosa-da-Silva S,Souza-Mello V

更新日期：2017-03-01 00:00:00

abstract：:Despite the majority of papillary thyroid microcarcinoma (PTMC) patients has benign clinical courses, some PTMCs have a clinical presentation similar to conventional papillary thyroid carcinoma (PTC). The aim of this study was to identify risk factors for lymph node metastasis at presentation and prognostic parameters...

journal_title：Endocrine

authors： Pisanu A,Saba A,Podda M,Reccia I,Uccheddu A

更新日期：2015-03-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroid glands, the anterior pituitary, and the endocrine pancreas. Our patient was a 58-year-old man who manifested typical features of MEN-1 including primary hyperparathyroidism, lung carcinoid, and lipom...

journal_title：Endocrine

authors： Nishiuchi T,Imachi H,Murao K,Fujiwara M,Muraoka T,Kikuchi F,Nishiuchi Y,Kushida Y,Haba R,Ishida T

更新日期：2009-08-01 00:00:00

abstract：:The adipocyte-derived catabolic protein leptin alters cell-mediated immunity and cytokine crosstalk. This may provide new insights into the altered immune response, seen in obese individuals. Therefore, we determined the tissue distribution of immune cells in diet-induced obese (dio) and normal weight F344 rats challe...

journal_title：Endocrine

authors： Behrendt P,Buchenauer T,Horn R,Brabant G,Jacobs R,Bode F,Stephan M,Nave H

更新日期：2010-08-01 00:00:00

abstract：:Aging can be defined as a progressive decline in the ability of the organism to resist stress, damage, and disease. Although there are currently over 300 theories to explain the aging phenomenon, it is still not well understood why organisms age and why the aging process can vary so much in speed and quality from indi...

journal_title：Endocrine

authors： Frisard M,Ravussin E

更新日期：2006-02-01 00:00:00

abstract：:Hypopituitarism reduces life expectancy and increases the risk of cardiovascular and cerebrovascular diseases, as well as death. Abnormalities in the cardiovascular system may be independently related to GH deficiency (GHD). The aim of this study was to prospectively investigate coronary flow reserve and diastolic fun...

journal_title：Endocrine

authors： Boschetti M,Agosti S,Albanese V,Casalino L,Teti C,Bezante GP,Brunelli C,Albertelli M,Ferone D

更新日期：2017-02-01 00:00:00

abstract：:This study was performed to ascertain whether a relationship exists between thyroid function and blood pressure in school-aged Chinese subjects without overt thyroid disease. A cross-sectional survey of 880 subjects (541 females and 339 males) aged 7-18 years in Bengbu, Anhui province was conducted. The investigation,...

journal_title：Endocrine

authors： Chen H,Xi Q,Zhang H,Song B,Liu X,Mao X,Li J,Shen H,Tang W,Zhang J,Wang Z,Duan Y,Liu C

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:11β-hydroxylase deficiency accounts for 5% of congenital adrenal hyperplasia cases. Diagnosis suspiction is classically based on the association between abnormal virilization, precocious puberty, and hypertension in 46XX or 46XY subjects. We investigated two families with siblings presenting with opposed clinic...

journal_title：Endocrine

authors： Valadares LP,Pfeilsticker ACV,de Brito Sousa SM,Cardoso SC,de Moraes OL,Gonçalves de Castro LC,de Oliveira RS,Lofrano-Porto A

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:Angiogenesis has been studied in pituitary neuroendocrine tumours (PitNETs), but the role of the tumour microenvironment (TME) in regulating PitNET angiogenesis remains unknown. We aimed to characterise the role of TME components in determining the angiogenetic PitNET profile, focusing on immune cells and tumou...

journal_title：Endocrine

authors： Marques P,Barry S,Carlsen E,Collier D,Ronaldson A,Dorward N,Grieve J,Mendoza N,Nair R,Muquit S,Grossman AB,Korbonits M

更新日期：2020-12-01 00:00:00

abstract：:Diabetes mellitus is a major risk factor for cardiovascular disease. However, the excess risk of death may vary substantially in subgroups of patients with type 2 diabetes, being highest in those younger than 55 years of age. A HbA1c value of 7.0 % or less is recommended for most patients with type 2 diabetes to reduc...

journal_title：Endocrine

authors： Giugliano D,Maiorino MI,Bellastella G,Esposito K

更新日期：2016-10-01 00:00:00

abstract：:The best repletion and maintenance dosing regimens with cholecalciferol in vitamin D-deficient HIV-1 patients remain unknown. Protease inhibitors (PIs) have been shown to inhibit vitamin D 1α- and 25α-hydroxylation in hepatocyte and monocyte cultures. We therefore evaluated the effect of a single high dose of cholecal...

journal_title：Endocrine

authors： Pepe J,Mezzaroma I,Fantauzzi A,Falciano M,Salotti A,Di Traglia M,Diacinti D,Biondi P,Cipriani C,Cilli M,Minisola S

更新日期：2016-07-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) acts as a nutrient-dependent insulin-releasing agent, and its insulinotropic action is enhanced by nutrient secretagogues, such as the dimethyl ester of succinic acid (SAD). In the present study, a primed constant infusion of SAD (0.5 micromol followed by 0.25 micromol/min both per g of...

journal_title：Endocrine

authors： Cancelas J,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Anti-Müllerian hormone (AMH) is crucial for folliculogenesis. Prenatal exposure to AMH in mice produces a phenocopy of polycystic ovary syndrome (PCOS) in the adult female offspring. The aim of this study was to determine whether genetic variation in AMH gene contribute to PCOS in women of Chinese ancestry. ME...

journal_title：Endocrine

authors： Qin L,Zhao S,Yang P,Cao Y,Zhang J,Chen ZJ,Dunaif A,Zhao H

更新日期：2020-11-09 00:00:00

abstract：:The purpose of the study was to determine whether impaired beta-cell function exists in Chinese individuals within the normal range of glucose tolerance (NGT), and these individuals are predisposed to diabetes later in life. The cross-sectional study included 843 NGT subjects and 562 isolated impaired glucose toleranc...

journal_title：Endocrine

authors： Lin Z,Zhou J,Li X,Song L,Hou X,Tang J,Wang C,Jia W

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Data from National Health and Nutrition Examination Survey (NHANES) for the years 2007-2012 were used to evaluate the interactions of cadmium (Cd) exposure with being overweight/obesity on the risk of prediabetes among adults 20 years older. METHODS:A total of 3552 subjects were included in the analysis. Urina...

journal_title：Endocrine

authors： Jiang F,Zhi X,Xu M,Li B,Zhang Z

更新日期：2018-08-01 00:00:00

abstract：:Estrogens regulate gene expression and cell proliferation in target tissues. In studies of estrogen-regulated gene expression, identification of appropriate housekeeping genes (HKGs), reference genes whose expression is not altered by treatment, is difficult. The goal of this study was to define HKGs unaltered by estr...

journal_title：Endocrine

authors： Schroder AL,Pelch KE,Nagel SC

更新日期：2009-04-01 00:00:00

abstract：:Thyroid hormone (TH) abnormalities are common in patients with diabetes mellitus (DM). These thyroid hormone abnormalities have been associated with inflammatory activity in several conditions but this link remains unclear in DM. We assessed the influence of subclinical inflammation in TH metabolism in euthyroid diabe...

journal_title：Endocrine

authors： Moura Neto A,Parisi MC,Alegre SM,Pavin EJ,Tambascia MA,Zantut-Wittmann DE

更新日期：2016-01-01 00:00:00

abstract：:Pituitary tumors are highly vascular neoplasms, which suggest an important role of angiogenesis in pituitary tumor growth. We used the human pituitary cell line (HP75) to examine the effects of the growth factors TGFbeta1, bFGF, and EGF on cell growth, and on the regulation of the pro-angiogenic growth factor VEGF-A a...

journal_title：Endocrine

authors： Horiguchi H,Jin L,Ruebel KH,Scheithauer BW,Lloyd RV

更新日期：2004-07-01 00:00:00

abstract：:Vertebral fractures are an emerging complication of acromegaly but their prediction is still difficult occurring even in patients with normal bone mineral density. In this study we evaluated the ability of high-resolution cone-beam computed tomography to provide information on skeletal abnormalities associated with ve...

journal_title：Endocrine

authors： Maffezzoni F,Maddalo M,Frara S,Mezzone M,Zorza I,Baruffaldi F,Doglietto F,Mazziotti G,Maroldi R,Giustina A

更新日期：2016-11-01 00:00:00

abstract：:Lactogen-dependent Nb2 lymphoma cells, widely employed for studying prolactin (PRL) mitogenic mechanisms, are also useful for investigations of apoptosis in T-lineage lymphocytes. Utilizing PRL-dependent Nb2-11 cultures, apoptosis-regulatory genes were evaluated for participation in dexamethasone- (DEX) provoked cell ...

journal_title：Endocrine

authors： Krumenacker JS,Buckley DJ,Leff MA,McCormack JT,de Jong G,Gout PW,Reed JC,Miyashita T,Magnuson NS,Buckley AR

更新日期：1998-10-01 00:00:00

abstract：:The androgen receptor (AR) plays a critical role in sexual differentiation and in the virilization of the male reproductive system. A clear understanding of AR expression at the early stages of sexual development will help elucidate the sensitivity of perinatal animals to endocrine modulation by external agents, such ...

journal_title：Endocrine

authors： You L,Sar M

更新日期：1998-12-01 00:00:00

abstract：:External ATP is believed to initiate and propagate Ca(2+) signals co-ordinating the insulin release pulses within and among the different islets in the pancreas. The possibility that islet endothelial cells participate in this process was evaluated by comparing the effects on [Ca(2+)](i) of purinoceptor activation in ...

journal_title：Endocrine

authors： Hellman B,Jansson L,Dansk H,Grapengiesser E

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To perform an online survey about the use of Thyroid Imaging Reporting and Data System (TIRADS) classification in Italy. METHODS:An online questionnaire was administered to all members of the Italian Society of Medical and Interventional Radiology (Società Italiana di Radiologia Medica ed Interventistica, SIRM...

journal_title：Endocrine

authors： Mauri G,Gitto S,Cantisani V,Vallone G,Schiavone C,Papini E,Sconfienza LM

更新日期：2020-05-01 00:00:00

abstract：:Subacute thyroiditis is a transient inflammatory thyroid disease of unknown etiology. The primary goal for treatment is to mitigate inflammation. The aim of this retrospective study was to compare the therapeutic effects of prednisolone and nonsteroidal anti-inflammation drugs in patients with subacute thyroiditis. In...

journal_title：Endocrine

authors： Sato J,Uchida T,Komiya K,Goto H,Takeno K,Suzuki R,Honda A,Himuro M,Watada H

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:A recent report described a new PCOS-like phenotype in lean older infertile women, and was characterized by high age-specific anti-Müllerian hormone (AMH) but hypo- rather than the expected hyper-androgenism. The hypo-androgenism was, furthermore, characterized of, likely, adrenal origin and autoimmune etiol...

journal_title：Endocrine

authors： Gleicher N,Kushnir VA,Darmon SK,Wang Q,Zhang L,Albertini DF,Barad DH

更新日期：2018-03-01 00:00:00

abstract：:Stimulation of dopamine D2 receptors inhibits melanotrope pro-opiomelanocortin (POMC) biosynthesis and alpha-melanocyte-stimulating hormone (MSH) secretion. These effects are mediated by G-protein alpha i- and alpha o-subunits and are reversed by stimulating receptors linked to activation of G alpha s protein. Melanot...

journal_title：Endocrine

authors： Sands SA,Dickerson DS,Morris SJ,Chronwall BM

更新日期：1997-06-01 00:00:00

abstract：PURPOSE:Diabetes mellitus (DM) has a multifactorial etiology that imparts a particular challenge to effective pharmacotherapy. Thyroid hormone actions have demonstrated beneficial effects in diabetic as well as obese rats. In both conditions, inflammation status plays a crucial role in the development of insulin resist...

journal_title：Endocrine

authors： Panveloski-Costa AC,Kuwabara WMT,Munhoz AC,Lucena CF,Curi R,Carpinelli AR,Nunes MT

更新日期：2020-05-01 00:00:00

abstract：:The objective was to determine molecular genetic analysis of the TPO gene in Turkish children with iodide organification defect (IOD). Patients with a diagnosis of primary hypothyroidism were evaluated. Subjects having a definite diagnosis of autoimmune thyroiditis, thyroid gland dysplasia and, or iodine deficiency we...

journal_title：Endocrine

authors： Turkkahraman D,Alper OM,Pehlivanoglu S,Aydin F,Yildiz A,Luleci G,Akcurin S,Bircan I

更新日期：2010-02-01 00:00:00