Comparison of the therapeutic effects of prednisolone and nonsteroidal anti-inflammatory drugs in patients with subacute thyroiditis.

Abstract:

:Subacute thyroiditis is a transient inflammatory thyroid disease of unknown etiology. The primary goal for treatment is to mitigate inflammation. The aim of this retrospective study was to compare the therapeutic effects of prednisolone and nonsteroidal anti-inflammation drugs in patients with subacute thyroiditis. In this study, 53 consecutive Japanese patients who had been diagnosed with were referred to our hospital for further management. After excluding 11 patients (9 did not need treatment, 2 did not meet the criteria for diagnosis of subacute thyroiditis), the remaining 42 patients were treated either with prednisolone (n = 25) or loxoprofen (n = 17). We compared the time periods required for resolution of clinical symptoms and signs and normalization of thyroid function between the two groups. The mean dose of prednisolone was 15.0 (range, 14-16) mg/day and that of loxoprofen was 180 mg/day. The time period to normalization of thyroid function was comparable between the prednisolone and loxoprofen groups (25, 18-36, vs 32, 21-39 days, p = 0.388). However, the time period for resolution of symptoms was shorter under prednisolone than loxoprofen (7, 7-12 days, vs 21, 14-32 days, p < 0.001). Prednisolone treatment of patients with subacute thyroiditis was superior to nonsteroidal anti-inflammation drugs with regard to resolution of symptoms.

journal_name

Endocrine

journal_title

Endocrine

authors

Sato J,Uchida T,Komiya K,Goto H,Takeno K,Suzuki R,Honda A,Himuro M,Watada H

doi

10.1007/s12020-016-1122-3

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

209-214

issue

1

eissn

1355-008X

issn

1559-0100

pii

10.1007/s12020-016-1122-3

journal_volume

55

pub_type

杂志文章
  • Transport of deoxy-D-glucose into lymphocytes of patients with polycystic ovary syndrome.

    abstract::Polycystic ovary syndrome (PCOS) is linked to increased risk of insulin resistance and diabetes mellitus in patients' later life. The aim of this study was to investigate uptake of deoxy-D-glucose by peripheral blood lymphocytes of PCOS patients with normal fasting plasma glucose and normal glucose tolerance test. The...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-014-0174-5

    authors: Oleszczak B,Szablewski L,Pliszka M,Głuszak O,Stopińska-Głuszak U

    更新日期:2014-11-01 00:00:00

  • Metachronous appearance of second malignancies in medullary thyroid carcinoma (MTC) patients: a diagnostic challenge and brief review of the literature.

    abstract::Medullary thyroid carcinoma (MTC) is a rare tumour which frequently occurs in the context of the multiple endocrine neoplasia syndromes, where it coexists with other usually benign tumours. The clinical picture varies and distant metastases are frequently present at diagnosis. Calcitonin levels are elevated in the pre...

    journal_title:Endocrine

    pub_type: 杂志文章,评审

    doi:10.1007/s12020-013-9961-7

    authors: Alevizaki M,Kyratzoglou E,Bamias A,Tzanela M,Dimopoulos MA,Saltiki K

    更新日期:2013-12-01 00:00:00

  • MicroRNA-17-92 cluster regulates osteoblast proliferation and differentiation.

    abstract::MicroRNAs (miRNAs) have been identified to play important functions during osteoblast proliferation, differentiation, and apoptosis. The miR-17~92 cluster is highly conserved in all vertebrates. Loss-of-function of the miR-17-92 cluster results in smaller embryos and immediate postnatal death of all animals. Germline ...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-013-9986-y

    authors: Zhou M,Ma J,Chen S,Chen X,Yu X

    更新日期:2014-03-01 00:00:00

  • Circulating microRNA-144-3p and miR-762 are novel biomarkers of Graves' disease.

    abstract:PURPOSE:Recently, it has been confirmed that circulating miRNAs play an important role in disease pathogenesis and can be biomarkers of many autoimmune diseases. However, the knowledge about circulating miRNAs in Graves' disease (GD) is very limited. In this study, we aimed to identify circulating miRNAs as potential b...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-019-01884-2

    authors: Yao Q,Wang X,He W,Song Z,Wang B,Zhang J,Qin Q

    更新日期:2019-07-01 00:00:00

  • Transport and metabolism of amino acids in placenta.

    abstract::In all mammalian species, the 20 amino acids of the genetic code are required for net protein accretion. The nutritional supply of amino acids for growth is defined as the net umbilical uptake of amino acids, representing the net transfer from maternal circulation, through the placenta and then to the fetus, of essent...

    journal_title:Endocrine

    pub_type: 杂志文章,评审

    doi:10.1385/ENDO:19:1:23

    authors: Regnault TR,de Vrijer B,Battaglia FC

    更新日期:2002-10-01 00:00:00

  • Steroid hormone receptors in target cell membranes.

    abstract::Numerous reports of rapid steroid hormone effects in diverse cell types cannot be explained by the generally prevailing theory that centers on the activity of hormone receptors located exclusively in the nucleus. Cell membrane forms of steroid hormone receptors coupled to intracellular signaling pathways may also play...

    journal_title:Endocrine

    pub_type: 杂志文章,评审

    doi:10.1385/ENDO:14:3:417

    authors: Pietras RJ,Nemere I,Szego CM

    更新日期:2001-04-01 00:00:00

  • Correction to: Malignant struma ovarii: next-generation sequencing of six cases revealed Nras, Braf, and Jak3 mutations.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Endocrine

    pub_type: 已发布勘误

    doi:10.1007/s12020-020-02514-y

    authors: Poli R,Scatolini M,Grosso E,Maletta F,Gallo M,Liscia D,Nelva A,Cesario F,Forte G,Metovic J,Volante M,Arvat E,Papotti M

    更新日期:2020-12-01 00:00:00

  • Natural course of hypogonadism diagnosed during hospitalization in aged male patients.

    abstract::Our aim was to assess short-term natural course of hypogonadism diagnosed during hospitalization for acute disease in aged male patients after discharge. A group of 43 hypogonadal males, aged 86.7±5.7 year, was studied. Serum concentrations of testosterone (T) and gonadotropins (follicle-stimulating hormone, FSH, and ...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-014-0417-5

    authors: Iglesias P,Prado F,Muñoz A,Guerrero MT,Macías MC,Ridruejo E,Tajada P,García-Arévalo C,Díez JJ

    更新日期:2015-04-01 00:00:00

  • Spectral domain optical coherence tomography based imaging biomarkers for diabetic retinopathy.

    abstract::To evaluate the role of central subfield thickness (CST), cube average thickness (CAT), and cube volume (CV) as imaging biomarkers for severity of diabetic retinopathy within the ETDRS-based grades of retinopathy using spectral domain optical coherence tomography (SD-OCT). This study aims to evaluate the role of macul...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-019-02093-7

    authors: Saxena S,Caprnda M,Ruia S,Prasad S,Ankita,Fedotova J,Kruzliak P,Krasnik V

    更新日期:2019-12-01 00:00:00

  • Changes in serum 25-hydroxyvitamin D and cholecalciferol after one whole-body exposure in a commercial tanning bed: a randomized study.

    abstract::We wanted to evaluate the cutaneous synthesis of 25OHD and cholecalciferol after one whole-body exposure to ultraviolet radiation type B (UVB) in a randomized setup. Healthy volunteers were randomized to one whole-body exposure in a commercial tanning bed with UVB emission (UVB/UVA ratio 1.8-2.0%) or an identical plac...

    journal_title:Endocrine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12020-012-9641-z

    authors: Langdahl JH,Schierbeck LL,Bang UC,Jensen JE

    更新日期:2012-10-01 00:00:00

  • Effect of colchicine and taxol on thyrotropin-releasing hormone receptor coupling to G protein in GH(3) cells.

    abstract::The role of membrane-associated tubulin in TRH receptor-G protein coupling was investigated with the use of compounds that influence tubulin function. TRH-stimulated G protein GTPase activity in GH(3) cell membranes was used to determine receptor-G protein coupling. TRH-stimulated GTPase activity was abolished by G(qα...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/BF02738873

    authors: Ravindra R,Forman LJ,Patel SA

    更新日期:1996-02-01 00:00:00

  • Dopamine D2 receptor stimulation alters G-protein expression in rat pituitary intermediate lobe melanotropes.

    abstract::Stimulation of dopamine D2 receptors inhibits melanotrope pro-opiomelanocortin (POMC) biosynthesis and alpha-melanocyte-stimulating hormone (MSH) secretion. These effects are mediated by G-protein alpha i- and alpha o-subunits and are reversed by stimulating receptors linked to activation of G alpha s protein. Melanot...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/BF02820510

    authors: Sands SA,Dickerson DS,Morris SJ,Chronwall BM

    更新日期:1997-06-01 00:00:00

  • Long-term outcome of multimodal therapy for giant prolactinomas.

    abstract::Giant prolactinomas are rare tumors characterized by their large size, compressive symptoms, and extremely high prolactin secretion. The aim of this study is to describe our experience with a series of 16 giant prolactinomas cases in terms of clinical presentation, therapeutic decisions, and final outcomes. Retrospect...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-016-1129-9

    authors: Andujar-Plata P,Villar-Taibo R,Ballesteros-Pomar MD,Vidal-Casariego A,Pérez-Corral B,Cabezas-Agrícola JM,Álvarez-Vázquez P,Serramito R,Bernabeu I

    更新日期:2017-01-01 00:00:00

  • Bullous pemphigoid and dipeptidyl peptidase-4 inhibitors: a meta-analysis of randomized controlled trials.

    abstract:PURPOSE:An increasing body of evidence suggests that dipeptidyl-peptidase 4 (DPP-4) inhibitors could play a role in the development of bullous pemphigoid. The knowledge regarding this association is based on case reports, pharmacovigilance database analyses, and observational studies. Data from randomized clinical tria...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-020-02272-x

    authors: Silverii GA,Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

    更新日期:2020-09-01 00:00:00

  • (99m)Tc-HYNIC-TOC scintigraphy in evaluation of active Graves' ophthalmopathy (GO).

    abstract:OBJECTIVE:A promising radiopharmaceutical (99m)Tc-HYNIC-TOC ((99m)Tc-HYNIC-Octreotide) can be applied for somatostatin receptor scintigraphy with the potential to replace Indium-111 labeled somatostatin analogus. Here we evaluate whether orbital (99m)Tc-HYNIC-TOC scintigraphy can be used as a Graves' ophthalmopathy (GO...

    journal_title:Endocrine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12020-007-0039-2

    authors: Sun H,Jiang XF,Wang S,Chen HY,Sun J,Li PY,Ning G,Zhao YJ

    更新日期:2007-06-01 00:00:00

  • Localization of growth hormone receptor messenger RNA in human tissues.

    abstract::In order to identify GH target cells in human tissues, we investigated the celiuiar distribution of human GH receptor (GHR) messenger RNA. This was performed byin situ hybridization and Northern blot hybridization using complementary radioactive DNA probe encoding part of the extracellular domain of the GHR. Several t...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/BF02990065

    authors: Mertani HC,Delehaye-Zervas MC,Martini JF,Postel-Vinay MC,Morel G

    更新日期:1995-02-01 00:00:00

  • Association between serum levels of adiponectin and polychlorinated biphenyls in Korean men and women.

    abstract::Persistent organic pollutants (POPs) are endocrine-disrupting chemicals associated with metabolic syndrome and type 2 diabetes. In humans, little is known about their potential role on obesity. Adiponectin augments the effects of insulin on glucose homeostasis. The expression of adiponectin is reduced in obesity, insu...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-014-0231-0

    authors: Lim JE,Jee SH

    更新日期:2015-02-01 00:00:00

  • High prevalence of thyroid ultrasonographic abnormalities in primary aldosteronism.

    abstract::The study was performed to evaluate the prevalence of thyroid abnormalities detected by ultrasonography and, in particular, of multinodular nontoxic goiter in primary aldosteronism. We analyzed 80 consecutive of patients with primary hyperaldosteronism (40 with unilateral adenoma and 40 with idiopathic hyperaldosteron...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1385/ENDO:22:2:155

    authors: Armanini D,Nacamulli D,Scaroni C,Lumachi F,Selice R,Fiore C,Favia G,Mantero F

    更新日期:2003-11-01 00:00:00

  • Treatment of adult growth hormone deficiency with human recombinant growth hormone: an update on current evidence and critical review of advantages and pitfalls.

    abstract::Adult-onset growth-hormone (GH) deficiency (GHD) is a rare disorder, which most commonly results from pituitary or peripituitary tumors and their treatment, and is characterized by alterations in body composition, carbohydrate and lipid metabolism, bone mineral density, cardiovascular risk profile and quality of life,...

    journal_title:Endocrine

    pub_type: 杂志文章,评审

    doi:10.1007/s12020-017-1492-1

    authors: Ramos-Leví AM,Marazuela M

    更新日期:2018-05-01 00:00:00

  • Interleukin-6 production and deregulation of the hypothalamic-pituitary-adrenal axis in patients with major depressive disorders.

    abstract::The present study was designed to determine whether an association exists between HPA activity and cytokine production in major depression (MD). In 9 patients with MD and 11 control subjects of both sexes, all drug-free, activity of the HPA axis was evaluated by circadian rhythm of plasma cortisol, 24-h free urinary c...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-006-0016-1

    authors: Humphreys D,Schlesinger L,Lopez M,Araya AV

    更新日期:2006-12-01 00:00:00

  • Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action.

    abstract::Central circuits known to regulate food intake and energy expenditure also affect central cardiovascular regulation. For example, both the melanocortin and neuropeptide Y (NPY) peptide families, known to regulate food intake, also produce central hypertensive effects. Members of both families share a similar C-termina...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-008-9141-3

    authors: Gruber KA,Fan W,Akerberg H,Larhammar D,Chee MJ,Colmers WF,Cone RD

    更新日期:2009-06-01 00:00:00

  • An assessment of the relationship between thyroid nodule characteristics, insulin resistance and arterial stiffness in euthyroid nodular goiter.

    abstract:OBJECTIVES:Publications suggesting that thyroid nodule might be associated with insulin resistance and metabolic syndrome are quite interesting. There is a need for studies assessing the relationship between nodule presence and cardiovascular risk in individuals with non-functioning nodular goiter. The purpose of the p...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-018-1701-6

    authors: Aydoğan Y,Altay M,Ünsal O,Kaplanoğlu V,Çağır Y,Yıldız C,Beyan E,Ramadan SU

    更新日期:2018-11-01 00:00:00

  • Polymorphisms in NR3C1 gene associated with risk of metabolic syndrome in a Chinese population.

    abstract::Polymorphisms of the NR3C1 (glucocorticoid receptor) gene have been reported to be associated with altered glucocorticoids sensitivity and changes in body composition and metabolic parameters. This study explored the relationship between single nucleotide polymorphisms (SNPs) of the NR3C1 gene and metabolic syndrome (...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-014-0324-9

    authors: Yan YX,Dong J,Zhang J,Liu F,Wang W,Zhang L,He Y

    更新日期:2014-12-01 00:00:00

  • CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves' disease and modulates clinical phenotype of disease.

    abstract::Graves' disease, an autoimmune disease with heterogeneous symptoms including Graves' orbitopathy, has a combined genetic/environmental background, where variations within CD28/CTLA-4/ICOS genes are considered as disease markers.Association of CD28c.17+3T>C(rs3116496), CTLA-4g.319C>T(rs5742909), CTLA-4c.49A>G(rs231775)...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-016-1096-1

    authors: Pawlak-Adamska E,Frydecka I,Bolanowski M,Tomkiewicz A,Jonkisz A,Karabon L,Partyka A,Nowak O,Szalinski M,Daroszewski J

    更新日期:2017-01-01 00:00:00

  • Antioxidative mechanisms and plasma growth hormone levels: potential relationship in the aging process.

    abstract::Factors affecting longevity are complex and poorly understood. We have recently found that Ames dwarf mice (df/df), which are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone, live significantly longer than their normal siblings whereas transgenic mice that overexpress GH exhibit reduced li...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1385/ENDO:11:1:41

    authors: Brown-Borg HM,Bode AM,Bartke A

    更新日期:1999-08-01 00:00:00

  • New technologies aiding dietary programmes for weight control: the oral glucose spray.

    abstract::To determine whether the administration of small amounts of glucose through an oral spray device (GSD) facilitates weight loss in overweight/obese subjects involved in a lifestyle modification programme. We randomly assigned 56 overweight/obese subjects to either the treatment group (n = 32) or the control group (n = ...

    journal_title:Endocrine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12020-013-9987-x

    authors: Khazrai YM,Maddaloni E,Altomare M,Cacciapaglia F,Pozzilli P

    更新日期:2014-03-01 00:00:00

  • Dual-energy X-ray absorptiometry pitfalls in Thalassemia Major.

    abstract:BACKGROUND:Low mineral mass and reduced bone strength with increased fracture risk are the main causes of morbidity in Thalassemia Major (TM). The pathogenesis is multifactorial and includes ineffective erythropoiesis with medullary expansion, multiple endocrine dysfunctions, direct iron bone deposition, deferoxamine-i...

    journal_title:Endocrine

    pub_type: 杂志文章,评审

    doi:10.1007/s12020-019-02003-x

    authors: Pellegrino F,Zatelli MC,Bondanelli M,Carnevale A,Cittanti C,Fortini M,Gamberini MR,Giganti M,Ambrosio MR

    更新日期:2019-09-01 00:00:00

  • Variation analysis of anti-Müllerian hormone gene in Chinese women with polycystic ovary syndrome.

    abstract:PURPOSE:Anti-Müllerian hormone (AMH) is crucial for folliculogenesis. Prenatal exposure to AMH in mice produces a phenocopy of polycystic ovary syndrome (PCOS) in the adult female offspring. The aim of this study was to determine whether genetic variation in AMH gene contribute to PCOS in women of Chinese ancestry. ME...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/s12020-020-02538-4

    authors: Qin L,Zhao S,Yang P,Cao Y,Zhang J,Chen ZJ,Dunaif A,Zhao H

    更新日期:2020-11-09 00:00:00

  • Cytoplasmic Ca2+ in glucagon-producing pancreatic alpha-cells exposed to carbachol and agents affecting Na+ fluxes.

    abstract::The cytoplasmic Ca2+ concentration ([Ca2+]i) was measured with dual wavelength fluorometry in glucagon-producing mouse pancreatic alpha-cells loaded with the indicator fura-2. Spontaneous rhythmic activity in terms of slow oscillations from a basal level was observed at 3 mM glucose. Like in the insulin-secreting beta...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1007/BF02738806

    authors: Berts A,Gylfe E,Hellman B

    更新日期:1997-02-01 00:00:00

  • Effect of ethanol on regulation of (Na + K)-adenosine triphosphatase by aldosterone and dexamethasone in cultured renal papillary collecting duct cells.

    abstract::Chronic ethanol exposure causes alterations in biologic membranes of different cell types. (Na + K) adenosine triphosphatase (ATPase), a membrane-bound enzyme inhibited by the acute presence of ethanol, increases its activity in rat kidney after chronic ethanol consumption. The aim of this investigation was to evaluat...

    journal_title:Endocrine

    pub_type: 杂志文章

    doi:10.1385/ENDO:19:3:301

    authors: Rodrigo R,Rivera G,Lucero Y,Larraguibel C

    更新日期:2002-12-01 00:00:00