Transport and metabolism of amino acids in placenta.

abstract：PURPOSE:Parathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited number of samples. The aim of the present study was to verify a group of mi...

journal_title：Endocrine

authors： Hu Y,Zhang X,Cui M,Su Z,Wang M,Liao Q,Zhao Y

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Diabetes self-management education is an essential part of diabetes care, but its impact on all-cause mortality risk of type 2 diabetes patients is unclear. A systematic review and meta-analysis aiming to elucidate the impact of diabetes self-management education on all-cause mortality risk of type 2 diabete...

journal_title：Endocrine

authors： He X,Li J,Wang B,Yao Q,Li L,Song R,Shi X,Zhang JA

更新日期：2017-03-01 00:00:00

abstract：:The present study investigates the effects of functional sensorial denervation, induced by administering capsaicin to hemiovariectomized adult female rats in each day of the estrus cycle, on ovulation and serum concentrations of estrogen and progesterone. The results indicate that the establishment of compensatory ova...

journal_title：Endocrine

authors： Trujillo A,Morales L,Vargas X,Alba L,Domínguez R

更新日期：2004-11-01 00:00:00

abstract：:Recently, an endogenous ligand has been described for the growth hormone secretagogue receptor (GHS-R), named ghrelin. It was originally isolated from the stomach, but it is also present in the hypothalamus, where the highest concentration of GHS-R has been detected. It is well established that synthetic GHSs exert th...

journal_title：Endocrine

authors： Korbonits M,Kojima M,Kangawa K,Grossman AB

更新日期：2001-02-01 00:00:00

abstract：:Ischemia-modified albumin (IMA) is a novel marker of tissue ischemia. Nowadays, IMA is accepted as a marker of oxidative stress. In this study, we aimed at establishing an association between IMA and hyperglycemia, blood pressure, lipid parameters, microvascular complications, hsCRP, and microalbuminuria in type 2 dia...

journal_title：Endocrine

authors： Ukinc K,Eminagaoglu S,Ersoz HO,Erem C,Karahan C,Hacihasanoglu AB,Kocak M

更新日期：2009-12-01 00:00:00

abstract：:To examine the effects of a structured group-based education programme, patient empowerment programme (PEP), compared with usual care on 2-year changes in patient-reported outcomes (PRO) in patients with diabetes mellitus (DM). A prospective observational study of 715 patients (PEP/non-PEP: 390/325) was conducted to c...

journal_title：Endocrine

authors： Wong CK,Lam CL,Wan EY,Chan AK,Pak CH,Chan FW,Wong WC

更新日期：2016-11-01 00:00:00

abstract：:Despite the availability of many new treatment options for type 2 diabetes, the proportion of patients achieving the HbA1c target < 7.0% remains around 50%. We put forward the hypothesis that the unchanged HbA1c results, observed in the last decade in type 2 diabetes patients, are also a consequence of medication nona...

journal_title：Endocrine

authors： Giugliano D,Maiorino MI,Bellastella G,Esposito K

更新日期：2018-07-01 00:00:00

abstract：:Variations in the fat mass and obesity-associated (FTO) gene have recently been associated with obesity and type 2 diabetes mellitus among different ethnic populations. Given that the phenotype of polycystic ovary syndrome (PCOS) overlaps with obesity and type 2 diabetes, we hypothesize that the common rs9939609 varia...

journal_title：Endocrine

authors： Yan Q,Hong J,Gu W,Zhang Y,Liu Q,Su Y,Zhang Y,Li X,Cui B,Ning G

更新日期：2009-12-01 00:00:00

abstract：:The present study was designed to monitor the correlation of gonadal steroidogenic activity and nitric oxide (NO) of plasma and testis of male laboratory mouse, Mus musculus, under (1) control/basal and (2) experimental conditions. In the first study, male mice (n = 6) of three age groups (3-week-old sexually immature...

journal_title：Endocrine

authors： Singh VP,Chaturvedi CM

更新日期：2014-08-01 00:00:00

abstract：:Intracranial tumors of different histologic types infrequently affect patients with pituitary adenomas and no history of head irradiation. The association with craniopharyngioma is extremely rare. Aims of this paper are: (1) to provide a critical literature review of typical features of pituitary adenoma presenting in...

journal_title：Endocrine

authors： Guaraldi F,Prencipe N,di Giacomo V,Scanarini M,Gasco V,Gardiman MP,Berton AM,Ghigo E,Grottoli S

更新日期：2013-08-01 00:00:00

abstract：:Leptin shows pleiotropic effects in organisms including an important role in the regulation of glucose homeostasis. Elevated serum leptin, particularly in obese individuals, is a warning sign of energy imbalance, hyperinsulinemia, insulin resistance and other metabolic risk factors that are strongly associated with ty...

journal_title：Endocrine

authors： Pliszka M,Oleszczak B,Szablewski L

更新日期：2015-05-01 00:00:00

abstract：:Persistent organic pollutants (POPs) are endocrine-disrupting chemicals associated with metabolic syndrome and type 2 diabetes. In humans, little is known about their potential role on obesity. Adiponectin augments the effects of insulin on glucose homeostasis. The expression of adiponectin is reduced in obesity, insu...

journal_title：Endocrine

authors： Lim JE,Jee SH

更新日期：2015-02-01 00:00:00

abstract：:Low 25(OH) vitamin D levels have been associated with several autoimmune diseases and recently with autoimmune thyroid disease (AITD). The aim of the study was to investigate the association of AITD with 25(OH) vitamin D levels in women with polycystic ovary syndrome (PCOS). Fifty women with PCOS were consecutively en...

journal_title：Endocrine

authors： Muscogiuri G,Palomba S,Caggiano M,Tafuri D,Colao A,Orio F

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Acromegaly is a systemic metabolic disease. Growth hormone (GH) have a significant impact on adipose tissue (AT). A huge reduction of serum GH after surgical treatment may cause substantial AT redistribution. The objective of this study was to illustrate the dynamic changes in distribution of facial and abdomin...

journal_title：Endocrine

authors： Xie T,Ding H,Xia M,Zhang X,Sun W,Liu T,Gu Y,Sun C,Hu F

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Fatty acid binding protein 4 (FABP4) has been demonstrated to be secreted from adipocytes in an unconventional pathway associated with lipolysis. Circulating FABP4 is elevated in metabolic disorders and has been shown to affect various peripheral cells such as pancreatic β-cells, hepatocytes and macrophages, bu...

journal_title：Endocrine

authors： Dou HX,Wang T,Su HX,Gao DD,Xu YC,Li YX,Wang HY

更新日期：2020-03-01 00:00:00

abstract：:A mechanism explaining the differential skeletal effects of intermittent and continuous elevation of serum parathyroid hormone (PTH) remains elusive. Intermittent PTH increases bone formation and bone mass and is being investigated as a therapy for osteoporosis. By contrast, chronic hyperparathyroidism results in the ...

journal_title：Endocrine

authors： Lotinun S,Sibonga JD,Turner RT

更新日期：2002-02-01 00:00:00

abstract：:Ovulation and conversion of the follicle into the corpus luteum involve remarkable changes in vascular permeability and neovascularization of the luteinizing granulosa layer. To evaluate the importance of these vascular events in follicle rupture and luteal development, sequential experiments were designed in which ve...

journal_title：Endocrine

authors： Hazzard TM,Rohan RM,Molskness TA,Fanton JW,D'Amato RJ,Stouffer RL

更新日期：2002-04-01 00:00:00

abstract：:Adult-onset growth-hormone (GH) deficiency (GHD) is a rare disorder, which most commonly results from pituitary or peripituitary tumors and their treatment, and is characterized by alterations in body composition, carbohydrate and lipid metabolism, bone mineral density, cardiovascular risk profile and quality of life,...

journal_title：Endocrine

authors： Ramos-Leví AM,Marazuela M

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Data on the prevalence and type of endocrine disorders in β-thalassemia intermedia (β-TI) patients are scarce. This multicenter study was designed to determine the prevalence of endocrine complications and the associated risk factors in a large group of β-TI patients. METHODS:In this cross-sectional multice...

journal_title：Endocrine

authors： Karimi M,Zarei T,Haghpanah S,Azarkeivan A,Kattamis C,Ladis V,Kattamis A,Kilinc Y,Daar S,Alyaarubi S,Khater D,Wali Y,Elshinawy M,Almadhani A,Yassin M,Soliman AT,Canatan D,Obiedat M,Al-Rimawi H,Mariannis D,Christodo

更新日期：2020-07-01 00:00:00

abstract：:Children born large for gestational age (LGA) may be at risk for development of obesity and insulin resistance (IR). The reciprocal relationship of adipokines and proinflammatory cytokines is suggested to play a putative role in fine tuning of insulin secretory dynamics. To evaluate serum interleukin-6 (IL-6), tumor n...

journal_title：Endocrine

authors： Cetin C,Baş F,Uçar A,Poyrazoğlu S,Saka N,Bundak R,Darendeliler F

更新日期：2014-12-01 00:00:00

abstract：:To further understand the role of ovarian hormones in the function of the serotonin neural system, we investigated the effects of estradiol (E), progesterone (P), and raloxifene on 5HT 1A and 2C receptor protein expression in the dorsal raphe region using Western blot analysis. Adult rhesus macaques (Macaca mulatta) w...

journal_title：Endocrine

authors： Henderson JA,Bethea CL

更新日期：2008-06-01 00:00:00

abstract：:To determine whether murine mammary growth is modulated by local insulin-like growth factor-1 (IGF-1) production, expression of recombinant IGF-1 was directed to the mammary glands of transgenic mice using an ovine prepro IGF-1 cDNA under control of the mouse mammary tumor virus-long terminal repeat (MMTV-LTR) promote...

journal_title：Endocrine

authors： Weber MS,Boyle PL,Corl BA,Wong EA,Gwazdauskas FC,Akers RM

更新日期：1998-06-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroid glands, the anterior pituitary, and the endocrine pancreas. Our patient was a 58-year-old man who manifested typical features of MEN-1 including primary hyperparathyroidism, lung carcinoid, and lipom...

journal_title：Endocrine

authors： Nishiuchi T,Imachi H,Murao K,Fujiwara M,Muraoka T,Kikuchi F,Nishiuchi Y,Kushida Y,Haba R,Ishida T

更新日期：2009-08-01 00:00:00

abstract：:Urocortin 3 (Ucn3) is recognized as a member of the corticotropin-releasing factor (CRF) family, which plays an important role in regulating food intake. We investigated the effects of centrally administered Ucn3 on food intake and gastric emptying in mice. Intracerebroventricular (ICV)administration of Ucn3 (0.1–1 nm...

journal_title：Endocrine

authors： Ushikai M,Asakawa A,Sakoguchi T,Tanaka C,Inui A

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:We exploited the MassARRAY (MA) genotyping platform to develop the "PTC-MA assay", which allows the simultaneous detection of 13 hotspot mutations, in the BRAF, KRAS, NRAS, HRAS, TERT, AKT1, PIK3CA, and EIF1AX genes, and six recurrent genetic rearrangements, involving the RET and TRK genes in papillary thyroid ...

journal_title：Endocrine

authors： Pesenti C,Muzza M,Colombo C,Proverbio MC,Farè C,Ferrero S,Miozzo M,Fugazzola L,Tabano S

更新日期：2018-07-01 00:00:00

abstract：:Thymic carcinoid is an important component of the tumor spectrum causing Ectopic ACTH Syndrome (EAS) and usually carries a poor prognosis. Efforts have been focused on exploring the mechanism of the excessive ACTH production in non-pituitary tumors, whereas few studies have reported the molecular events underlying the...

journal_title：Endocrine

authors： Liu RX,Wang WQ,Ye L,Bi YF,Fang H,Cui B,Zhou WW,Dai M,Zhang J,Li XY,Ning G

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:A large number of studies has investigated proopiomelanocortin processing in anterior pituitary corticotropes but little is known on proopiomelanocortin/ACTH degradation within these cells. The ubiquitin-proteasome system is an intracellular protein degradation pathway which has garnered considerable interest i...

journal_title：Endocrine

authors： Sesta A,Cassarino MF,Cavagnini F,Pecori Giraldi F

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:An increasing body of evidence suggests that dipeptidyl-peptidase 4 (DPP-4) inhibitors could play a role in the development of bullous pemphigoid. The knowledge regarding this association is based on case reports, pharmacovigilance database analyses, and observational studies. Data from randomized clinical tria...

journal_title：Endocrine

authors： Silverii GA,Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Changes in body composition are commonly present in chronic obstructive pulmonary disease (COPD). The main aim of this study were to evaluate changes in body composition and the prevalence of pre-sarcopenia and sarcopenia in patients with COPD, compared with two control groups and correlate these parameters wit...

journal_title：Endocrine

authors： Munhoz da Rocha Lemos Costa T,Costa FM,Jonasson TH,Moreira CA,Boguszewski CL,Borba VZC

更新日期：2018-04-01 00:00:00

abstract：:The effects of endomorphin-1 (EM1) on behavioral responses and on the hypothalamic-pituitary-adrenal system were investigated in mice. Locomotor activity was measured in an "open-field" apparatus, with parallel recording of the numbers of rearings and groomings. Different doses of the peptide (250 ng to 5 microg) were...

journal_title：Endocrine

authors： Bujdosó E,Jászberényi M,Tömböly C,Tóth G,Telegdy G

更新日期：2001-03-01 00:00:00