Low 25 (OH) vitamin D levels are associated with autoimmune thyroid disease in polycystic ovary syndrome.

abstract：PURPOSE:Hormonal status and menopause affect human macrophage function and cardiometabolic risk. In polycystic ovary syndrome (PCOS) patients the cardiometabolic risk increases through mechanisms that are largely unknown. We tested the hypotheses that macrophage activation is influenced by menstrual cycle and that ovar...

journal_title：Endocrine

authors： Tedesco S,Adorni MP,Ronda N,Cappellari R,Mioni R,Barbot M,Pinelli S,Plebani M,Bolego C,Scaroni C,Bernini F,Fadini GP,Cignarella A

更新日期：2019-11-01 00:00:00

abstract：:To investigate the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey. Seventy-six patients with CPHD were included in this study. Based on clinical, hormonal, and neuro-radiological data, relevant transcription factor genes were evaluated...

journal_title：Endocrine

authors： Baş F,Uyguner ZO,Darendeliler F,Aycan Z,Çetinkaya E,Berberoğlu M,Şiklar Z,Öcal G,Darcan Ş,Gökşen D,Topaloğlu AK,Yüksel B,Özbek MN,Ercan O,Evliyaoğlu O,Çetinkaya S,Şen Y,Atabek E,Toksoy G,Aydin BK,Bundak R

更新日期：2015-06-01 00:00:00

abstract：:Regular endurance exercise promotes metabolic and oxidative changes in skeletal muscle. Overexpression of interleukin-15 (IL-15) in mice exerts similar metabolic changes in muscle as seen with endurance exercise. Muscular IL-15 production has been shown to increase in mice after weeks of regular endurance running. Wit...

journal_title：Endocrine

authors： Rinnov A,Yfanti C,Nielsen S,Akerström TC,Peijs L,Zankari A,Fischer CP,Pedersen BK

更新日期：2014-03-01 00:00:00

abstract：:Increasing evidence suggests that inflammatory response may be a critical component of different brain pathologies. However, the role played by this reaction is not fully understood. The present findings suggest that neuroinflammtory mediators such as cytokines may be involved in a number of key steps in the pathologi...

journal_title：Endocrine

authors： Członkowska A,Ciesielska A,Gromadzka G,Kurkowska-Jastrzebska I

更新日期：2006-04-01 00:00:00

abstract：:Erectile dysfunction (ED) is commonly associated with risk factors for cardiovascular disease, including diabetes. The prevalence of ED in diabetic patients is high--about 75% of diabetic men 60 yr of age or older had ED in one study. Endothelial dysfunction, accelerated atherosclerosis, and diabetic neuropathy likely...

journal_title：Endocrine

authors： Kloner RA

更新日期：2004-03-01 00:00:00

abstract：:Homozygous Klotho mutant (kl-/-) mice exhibit a variety of phenotypes resembling human aging, including arteriosclerosis, infertility, skin atrophy, osteoporosis, and short life span. Calcium abnormality, one of the phenotypes in kl-/- mice, is thought to be due to the elevated gene expression of 25-hydroxyvitamin D3 ...

journal_title：Endocrine

authors： Imai M,Ishikawa K,Matsukawa N,Kida I,Ohta J,Ikushima M,Chihara Y,Rui X,Rakugi H,Ogihara T

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Several conditions can modify the intestinal absorption of levothyroxine tablets, with potential consequences on their therapeutic effect. Pre-dosed ampoules and oral drops have been recently made available to overcome this limitation. AIMS:To describe the pattern of use of different formulations of levothy...

journal_title：Endocrine

authors： Ferrara R,Ientile V,Arcoraci V,Ferrajolo C,Piccinni C,Fontana A,Benvenga S,Trifirò G

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Wolfram syndrome (WFS) is a rare, monogenic neurodegenerative syndrome characterised by insulin requiring non-autoimmune diabetes mellitus (DM) and optic atrophy which are usually the earliest and commonest manifestations. However, there are other features which are under-recognized, adding to morbidity and ...

journal_title：Endocrine

authors： Das L,Rai A,Mavuduru R,Vaiphei K,Sharma A,Gupta V,Bhadada SK,Lodha S,Panda N,Bhansali A,Singh P,Dutta P

更新日期：2020-08-01 00:00:00

abstract：:Glucose-6-phosphate dehydrogenase (G6PD) deficiency predisposes affected individuals highly susceptible to oxidative stress, which is one of the risk factors for diabetes. To evaluate the relationship between blood level of G6PD activity and diabetes in Taiwan, blood G6PD activity was analyzed among 237 patients with ...

journal_title：Endocrine

authors： Wan GH,Tsai SC,Chiu DT

更新日期：2002-11-01 00:00:00

abstract：:Cytoplasmic calcium ([Ca(2+)](i)) changes evoked by adenosine 5(1)-triphosphate (ATP) were recorded in cultured individual Leydig cells within 10-18 h after cell dispersion. [Ca(2+)](i) was monitored using Fura-2AM loaded cells with a digital ratio imaging system. Five micromolars ATP induced biphasic [Ca(2+)](i) resp...

journal_title：Endocrine

authors： Pérez-Armendariz EM,Nadal A,Fuentes E,Spray DC

更新日期：1996-06-01 00:00:00

abstract：:To evaluate whether continuous subcutaneous insulin infusion (CSII) may have any advantage over multiple daily injections (MDI) on glycemic control and treatment satisfaction in young patients with Type 1 diabetes in transition to an adult diabetes center. The study population consisted of 125 patients on MDI; 38 out ...

journal_title：Endocrine

authors： Maiorino MI,Bellastella G,Petrizzo M,Improta MR,Brancario C,Castaldo F,Olita L,Giugliano D

更新日期：2014-06-01 00:00:00

abstract：:The process of homo- and/or heterodimerization of G-protein coupled receptors (GPCRs) and receptor tyrosine kinase (RTK) families are crucial for implicating the fundamental properties of receptor proteins including receptor expression, trafficking, and desensitization as well as signal transduction. The members of GP...

journal_title：Endocrine

authors： Kumar U

更新日期：2011-10-01 00:00:00

abstract：:We validated the effect of prolactin-releasing peptide (PrRP) on prolactin (PRL) secretion from rat anterior pituitary cells in in vitro culture. We found that culture conditions considerably influenced the response of the anterior pituitary cells to PrRP. Longer culture term (4 d) was required to obtain better respon...

journal_title：Endocrine

authors： Kawamata Y,Fujii R,Fukusumi S,Habata Y,Hosoya M,Hinuma S,Kitada C,Onda H,Nishimura O,Fujino M

更新日期：2000-06-01 00:00:00

abstract：:The adipocyte-derived catabolic protein leptin alters cell-mediated immunity and cytokine crosstalk. This may provide new insights into the altered immune response, seen in obese individuals. Therefore, we determined the tissue distribution of immune cells in diet-induced obese (dio) and normal weight F344 rats challe...

journal_title：Endocrine

authors： Behrendt P,Buchenauer T,Horn R,Brabant G,Jacobs R,Bode F,Stephan M,Nave H

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:We exploited the MassARRAY (MA) genotyping platform to develop the "PTC-MA assay", which allows the simultaneous detection of 13 hotspot mutations, in the BRAF, KRAS, NRAS, HRAS, TERT, AKT1, PIK3CA, and EIF1AX genes, and six recurrent genetic rearrangements, involving the RET and TRK genes in papillary thyroid ...

journal_title：Endocrine

authors： Pesenti C,Muzza M,Colombo C,Proverbio MC,Farè C,Ferrero S,Miozzo M,Fugazzola L,Tabano S

更新日期：2018-07-01 00:00:00

abstract：:The familial forms of non-medullary thyroid carcinoma (FNMTC) represent approximately 5 % of thyroid neoplasms. Nine FNMTC susceptibility loci have been mapped; however, only the DICER1 and SRGAP1 susceptibility genes have been identified. The transcription factors NKX2-1, FOXE1, PAX8, and HHEX are involved in the mor...

journal_title：Endocrine

authors： Pereira JS,da Silva JG,Tomaz RA,Pinto AE,Bugalho MJ,Leite V,Cavaco BM

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:Recently, it has been confirmed that circulating miRNAs play an important role in disease pathogenesis and can be biomarkers of many autoimmune diseases. However, the knowledge about circulating miRNAs in Graves' disease (GD) is very limited. In this study, we aimed to identify circulating miRNAs as potential b...

journal_title：Endocrine

authors： Yao Q,Wang X,He W,Song Z,Wang B,Zhang J,Qin Q

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Thyroid hormone (TH) metabolism can have prognostic significance in brain tumors. We studied the association of common variations in three deiodinase gene single-nucleotide polymorphisms (SNPs) with circulating TH concentrations and prognosis of brain tumor patients. METHODS:Patients admitted for glioma and...

journal_title：Endocrine

authors： Bunevicius A,Laws ER,Saudargiene A,Tamasauskas A,Iervasi G,Deltuva V,Smith TR,Bunevicius R

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Rathke's cleft cysts (RCC) are lesions that arise from Rathke's pouch. Though frequently incidental, resulting symptoms in a minority of cases are indicators for surgical resection, which may prove beneficial. OBJECTIVE:To characterize a cohort of surgically-resected RCC cases at Oregon Health & Science Uni...

journal_title：Endocrine

authors： Langlois F,Manea A,Lim DST,McCartney S,Yedinak CG,Cetas JS,Fleseriu M

更新日期：2019-03-01 00:00:00

abstract：:We wanted to evaluate the cutaneous synthesis of 25OHD and cholecalciferol after one whole-body exposure to ultraviolet radiation type B (UVB) in a randomized setup. Healthy volunteers were randomized to one whole-body exposure in a commercial tanning bed with UVB emission (UVB/UVA ratio 1.8-2.0%) or an identical plac...

journal_title：Endocrine

authors： Langdahl JH,Schierbeck LL,Bang UC,Jensen JE

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:We retrospectively evaluated all patients with pituitary tumours treated in our department from 1/1/1997 to 01/11/2014. PATIENTS AND METHODS:Two hundred and fifteen patients (124 females, 91 males, mean age 50.9 years) were treated because of pituitary tumours. All patients underwent basal hormonal analys...

journal_title：Endocrine

authors： Askitis D,Tsitlakidis D,Müller N,Waschke A,Wolf G,Müller UA,Kloos C

更新日期：2018-05-01 00:00:00

abstract：:A great number of prospective studies have investigated the relationship between leisure time physical activity (LTPA) and metabolic syndrome (MetS) risk. However, the results have been inconsistent. The aim of this study was to clarify the relationship between LTPA and MetS risk. Literature databases were searched in...

journal_title：Endocrine

authors： He D,Xi B,Xue J,Huai P,Zhang M,Li J

更新日期：2014-06-01 00:00:00

abstract：:Thyroid hormone (TH) abnormalities are common in patients with diabetes mellitus (DM). These thyroid hormone abnormalities have been associated with inflammatory activity in several conditions but this link remains unclear in DM. We assessed the influence of subclinical inflammation in TH metabolism in euthyroid diabe...

journal_title：Endocrine

authors： Moura Neto A,Parisi MC,Alegre SM,Pavin EJ,Tambascia MA,Zantut-Wittmann DE

更新日期：2016-01-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) and somatostatin are the most important hypothalamic neurohormones controlling growth hormone (GH) secretion. Several neurotransmitters and neuropeptides also play an important role in the control of GH secretion, mainly acting via modulation of GHRH and somatostatin. In the pas...

journal_title：Endocrine

authors： Arvat E,Gianotti L,Giordano R,Broglio F,Maccario M,Lanfranco F,Muccioli G,Papotti M,Graziani A,Ghigo E,Deghenghi R

更新日期：2001-02-01 00:00:00

abstract：:Despite the majority of papillary thyroid microcarcinoma (PTMC) patients has benign clinical courses, some PTMCs have a clinical presentation similar to conventional papillary thyroid carcinoma (PTC). The aim of this study was to identify risk factors for lymph node metastasis at presentation and prognostic parameters...

journal_title：Endocrine

authors： Pisanu A,Saba A,Podda M,Reccia I,Uccheddu A

更新日期：2015-03-01 00:00:00

abstract：:This study tested the hypothesis that aromatization of testosterone to estradiol is necessary for sexual differentiation of the sheep brain. Pregnant ewes (n = 10) were treated with the aromatase inhibitor 1,4,6- androstatriene-3,17-dione (ATD) during the period of gestation when the sheep brain is maximally sensitive...

journal_title：Endocrine

authors： Roselli CE,Schrunk JM,Stadelman HL,Resko JA,Stormshak F

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:The study aimed to disclose mortality pattern and quantitatively evaluate risks for cause-specific mortality among thyroid cancer survivors. METHODS:We included 173,710 patients from the Surveillance, Epidemiology, and End Results (SEER) database with thyroid cancer diagnosed between 1975 and 2015. Standardize...

journal_title：Endocrine

authors： Du B,Wang F,Wu L,Wang Z,Zhang D,Huang Z,Gao L,Li Y,Liang C,Li P,Yao R

更新日期：2020-08-08 00:00:00

abstract：:The A1 adenosine receptor (A1AR) exerts important biological effects in the mammalian biology. To provide insights into the role A1AR action in human physiology, we characterized the pharmacologic properties of the human A1AR, examined somatic sites of A1AR gene expression, and identified the chromosomal location of t...

journal_title：Endocrine

authors： Rivkees SA,Lasbury ME,Stiles GS,Henegariu O,Curtis C,Vance G

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Patients with cortisol secreting adrenal adenomas present with Cushing's syndrome (CS), while 5-15% of subjects with adrenal incidentalomas have subclinical hypercortisolism (SH) as they have biochemical abnormalities suggesting autonomous cortisol secretion without associated clinical features of CS. GOALS...

journal_title：Endocrine

authors： Khawandanah D,ElAsmar N,Arafah BM

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:This study aimed to evaluate the effectiveness of ultrasound (US)-guided radiofrequency ablation (RFA) treatment of benign thyroid nodules in consecutive large number series. To find out whether there is any difference according to the nature of the nodules, nodules were subdivided into two groups of predominan...

journal_title：Endocrine

authors： Lee GM,You JY,Kim HY,Chai YJ,Kim HK,Dionigi G,Tufano RP

更新日期：2019-05-01 00:00:00