Decreased blood activity of glucose-6-phosphate dehydrogenase associates with increased risk for diabetes mellitus.

abstract：PURPOSE:Multiple endocrine neoplasia type 1 is a rare tumor syndrome caused by germline mutations of MEN1 gene. Phenotype varies widely, and no definitive correlation with the genotype has been observed. Mutation-negative patients with MEN1-associated tumors represent phenocopies. By comparing mutation-positive and mut...

journal_title：Endocrine

authors： Kövesdi A,Tóth M,Butz H,Szücs N,Sármán B,Pusztai P,Tőke J,Reismann P,Fáklya M,Tóth G,Somogyi A,Borka K,Erdei A,Nagy EV,Deák V,Valkusz Z,Igaz P,Patócs A,Grolmusz VK

更新日期：2019-08-01 00:00:00

abstract：:Asymmetric mRNA expression was found in preoptic anterior and hypothalamic anterior areas of the two estrogen receptor isoforms and the gonadotropin-releasing hormone. On the right side of these areas, estrogen receptor alpha mRNA expression reached its peak on estrus day, while on the left side the peak was reached o...

journal_title：Endocrine

authors： Arteaga-López PR,Domínguez R,Cerbón MA,Mendoza-Rodríguez CA,Cruz ME

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:The study aimed to disclose mortality pattern and quantitatively evaluate risks for cause-specific mortality among thyroid cancer survivors. METHODS:We included 173,710 patients from the Surveillance, Epidemiology, and End Results (SEER) database with thyroid cancer diagnosed between 1975 and 2015. Standardize...

journal_title：Endocrine

authors： Du B,Wang F,Wu L,Wang Z,Zhang D,Huang Z,Gao L,Li Y,Liang C,Li P,Yao R

更新日期：2020-08-08 00:00:00

abstract：:Peptide hormones are generated by proteolytic processing of their respective protein precursors by several prohormone processing proteases. The peptide hormone PTHrP is widely expressed in normal and malignant tissues, where proPTHrP undergoes proteolytic processing to generate PTHrP peptides with distinct biological ...

journal_title：Endocrine

authors： Deftos LJ,Burton D,Hastings RH,Terkeltaub R,Hook VY

更新日期：2001-07-01 00:00:00

abstract：:To investigate the role of NAMPT/visfatin in euthyroid patients with Graves' disease without (GD) and with Graves' ophthalmopathy (GO), we analyzed NAMPT leukocyte expression and its serum concentration. This was a single-center, cross-sectional study with consecutive enrollment. In total, 149 patients diagnosed with ...

journal_title：Endocrine

authors： Sawicka-Gutaj N,Budny B,Zybek-Kocik A,Sowiński J,Ziemnicka K,Waligórska-Stachura J,Ruchała M

更新日期：2016-08-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroid glands, the anterior pituitary, and the endocrine pancreas. Our patient was a 58-year-old man who manifested typical features of MEN-1 including primary hyperparathyroidism, lung carcinoid, and lipom...

journal_title：Endocrine

authors： Nishiuchi T,Imachi H,Murao K,Fujiwara M,Muraoka T,Kikuchi F,Nishiuchi Y,Kushida Y,Haba R,Ishida T

更新日期：2009-08-01 00:00:00

abstract：:Variants of growth hormone (GH) are present in most vertebrates. Chicken GH (cGH) undergoes posttranslational modifications that contribute to its structural diversity. Although the 22-kDa form of GH is the most abundant, some other variants have discrete bioactivities that may not be shared by others. The proportion ...

journal_title：Endocrine

authors： Martínez-Coria H,López-Rosales LJ,Carranza M,Berumen L,Luna M,Arámburo C

更新日期：2002-03-01 00:00:00

abstract：:Recently, the microhistologic evaluation by core needle biopsy (CNB) has been reported as high accurate to diagnose thyroid nodules with previous indeterminate or not adequate fine-needle aspiration cytology. In addition, sparse data have been reported regarding the use of CNB in other conditions. Aim of this review w...

journal_title：Endocrine

authors： Trimboli P,Crescenzi A

更新日期：2015-04-01 00:00:00

abstract：:This study examined the interrelationship between transforming growth factor-beta1 (TGF-beta1) and 17beta-estradiol (E2) in the regulation of growth plate chondrocytes. To determine whether TGF-beta1 modulates chondrocyte response to E2, we used cells isolated from the resting zone (RC) and growth zone (GC) of costoch...

journal_title：Endocrine

authors： Nasatzky E,Grinfeld D,Boyan BD,Dean DD,Ornoy A,Schwartz Z

更新日期：1999-12-01 00:00:00

abstract：:Environmental toxicants are thought to play a role in several estrogen-dependent diseases including breast cancer and endometriosis. Toxicant-induced increased aromatase activity, an enzyme complex that catalyzes the final rate-limiting step in the conversion of androgens to estrogens, has been reported in assays usin...

journal_title：Endocrine

authors： Holloway AC,Stys KA,Foster WG

更新日期：2005-06-01 00:00:00

abstract：:The objective was to determine molecular genetic analysis of the TPO gene in Turkish children with iodide organification defect (IOD). Patients with a diagnosis of primary hypothyroidism were evaluated. Subjects having a definite diagnosis of autoimmune thyroiditis, thyroid gland dysplasia and, or iodine deficiency we...

journal_title：Endocrine

authors： Turkkahraman D,Alper OM,Pehlivanoglu S,Aydin F,Yildiz A,Luleci G,Akcurin S,Bircan I

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:Metabolic syndrome (MetS) is a constellation of clinical factors that indicates elevated risk of diabetes. It is diagnosed based on three or more abnormalities in its components. This does not take into account that MetS can likely present as a continuum of risk. We aim to develop a MetS severity score and asse...

journal_title：Endocrine

authors： Low S,Khoo KCJ,Wang J,Irwan B,Sum CF,Subramaniam T,Lim SC,Wong TKM

更新日期：2019-07-01 00:00:00

abstract：:Ischemia-modified albumin (IMA) is a novel marker of tissue ischemia. Nowadays, IMA is accepted as a marker of oxidative stress. In this study, we aimed at establishing an association between IMA and hyperglycemia, blood pressure, lipid parameters, microvascular complications, hsCRP, and microalbuminuria in type 2 dia...

journal_title：Endocrine

authors： Ukinc K,Eminagaoglu S,Ersoz HO,Erem C,Karahan C,Hacihasanoglu AB,Kocak M

更新日期：2009-12-01 00:00:00

abstract：:Overproduction of proinflammatory factors is associated with obesity and diabetes. Interleukin (IL)-18 as a member of IL-1 cytokine family is increased in obese, in diabetic, and even in polycystic ovary syndrome (PCOS) patients. In the present study we evaluated the association of serum IL-18 levels with insulin resi...

journal_title：Endocrine

authors： Zhang YF,Yang YS,Hong J,Gu WQ,Shen CF,Xu M,Du PF,Li XY,Ning G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate premature mortality and the risk of cardiovascular disease (CVD) in Chinese adults with diabetes diagnosed before the age of 45 years. METHODS:A total of 519 participants with normal glucose tolerance (NGT) and 630 with newly diagnosed diabetes mellitus (DM) were recruited in ...

journal_title：Endocrine

authors： Hui Y,Wang J,An Y,Gong Q,Li H,Zhang B,Shuai Y,Chen Y,Hu Y,Li G

更新日期：2019-07-01 00:00:00

abstract：:Central circuits known to regulate food intake and energy expenditure also affect central cardiovascular regulation. For example, both the melanocortin and neuropeptide Y (NPY) peptide families, known to regulate food intake, also produce central hypertensive effects. Members of both families share a similar C-termina...

journal_title：Endocrine

authors： Gruber KA,Fan W,Akerberg H,Larhammar D,Chee MJ,Colmers WF,Cone RD

更新日期：2009-06-01 00:00:00

abstract：:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are relatively rare and heterogenous malignancies. Recent advances in histopathological classification according to the anatomical site of origin, proliferation rate, and extend of the disease have created a valid and powerful tool for the prognostic stratificati...

journal_title：Endocrine

authors： Alexandraki KI,Kaltsas G

更新日期：2012-02-01 00:00:00

abstract：:Remarkable decreases in growth hormone (GH) secretion accompany healthy aging. The pathophysiology of this hyposomatotropism is confounded by concurrent changes in body composition (with increased visceral fat), physiological declines in estrogen and androgen concentrations, differences in gender responses to aging, a...

journal_title：Endocrine

authors： Veldhuis JD,Iranmanesh A,Weltman A

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:The influence of the dipeptidyl peptidase-IV inhibitor, gemigliptin alone or in combination with metformin on survival, proliferation, and migration of thyroid carcinoma cells was investigated. METHODS:SW1736 and TPC-1 human thyroid carcinoma cells were used. RESULTS:Gemigliptin and metformin caused cell deat...

journal_title：Endocrine

authors： Kim SH,Kang JG,Kim CS,Ihm SH,Choi MG,Yoo HJ,Lee SJ

更新日期：2018-02-01 00:00:00

abstract：UNLABELLED:Gallium-68 somatostatin receptor (SMSR) positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) are valuable diagnostic tools for patients with neuroendocrine tumours (NETs). To date, a meta-analysis about the diagnostic accuracy of these imaging methods is lacking. A...

journal_title：Endocrine

authors： Treglia G,Castaldi P,Rindi G,Giordano A,Rufini V

更新日期：2012-08-01 00:00:00

abstract：:The aim of the study was to assess the impact of sex hormone-binding globulin (SHBG) on bone mineral density (BMD) and bone turnover among Chinese middle-aged and elderly men. This cross-sectional study was carried out among 404 Chinese men aged over 45 years. BMD was measured with dual-energy X-ray absorptiometry, an...

journal_title：Endocrine

authors： Zha XY,Hu Y,Pang XN,Zhu JH,Chang GL,Li L

更新日期：2014-11-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) patients treated with thyroidectomy and radioiodine remnant ablation (RRA) often have detectable TSH-stimulated thyroglobulin (Tg) levels without localizable disease after primary treatment. To assess the value of repeat stimulated Tg assays in these patients' follow-up, we retrospective...

journal_title：Endocrine

authors： Lamartina L,Montesano T,Trulli F,Attard M,Torlontano M,Bruno R,Meringolo D,Monzani F,Tumino S,Ronga G,Maranghi M,Biffoni M,Filetti S,Durante C

更新日期：2016-11-01 00:00:00

abstract：:Estrogens increase prolactin (PRL) synthesis and release in rats and humans, whereas pituitary-derived calcitonin-like immunoreactive peptide (pit-CT) inhibits PRL gene expression and release. To test the hypothesis that estrogens stimulate lactotrophs by diminishing pit-CT expression, the present studies examined eff...

journal_title：Endocrine

authors： Li Z,Shah GV

更新日期：1995-06-01 00:00:00

abstract：:To investigate the adrenal effect of a phytosterol (PS) additive, 80 male Japanese quail were divided into four sub-groups and fed 0, 40, 400, and 4,000 ppm of PS, respectively, for 21 days. Subsequently, 50% of the birds from each dosage group were subjected to a 6-day adrenal function test, whereby they were injecte...

journal_title：Endocrine

authors： Liu F,Chen J,Shi F,Wang T,Watanabe G,Taya K

更新日期：2012-04-01 00:00:00

abstract：:Previous evidence supports the view that insulin, as well as insulin like growth factor-1 (IGF-1) provides neurotropic support for neurons in the central nervous system (CNS) and peripheral nervous system (PNS). In the present study we evaluated the effects of the intravenous infusion of IGF-1 on both necrosis and apo...

journal_title：Endocrine

authors： Rizk NN,Myatt-Jones J,Rafols J,Dunbar JC

更新日期：2007-02-01 00:00:00

abstract：:The therapeutic activity of 131I administered to patients with Graves' disease can be calculated by means of Marinelli's formula. The thyroidal iodine uptake (131IUmax) needed for the calculation is usually determined with the use of 131I. The purpose of the paper was to estimate 131IUmax on the basis of technetium up...

journal_title：Endocrine

authors： Szumowski P,Mojsak M,Abdelrazek S,Sykała M,Amelian-Fiłonowicz A,Jurgilewicz D,Myśliwiec J

更新日期：2016-12-01 00:00:00

abstract：:Thyroid hormones are now recognized to change in different disease states with important consequences on severity and prognosis of disease. However, little is known about thyroid hormones' alterations in acute liver failure (ALF). To study the changes in thyroid hormones and cardiac thyroid receptors during ALF, we su...

journal_title：Endocrine

authors： Kostopanagiotou G,Kalimeris K,Mourouzis I,Kostopanagiotou K,Arkadopoulos N,Panagopoulos D,Papoutsidakis N,Chranioti A,Pafiti A,Spanou D,Smyrniotis V,Pantos C

更新日期：2009-10-01 00:00:00

abstract：:Low 25(OH) vitamin D levels have been associated with several autoimmune diseases and recently with autoimmune thyroid disease (AITD). The aim of the study was to investigate the association of AITD with 25(OH) vitamin D levels in women with polycystic ovary syndrome (PCOS). Fifty women with PCOS were consecutively en...

journal_title：Endocrine

authors： Muscogiuri G,Palomba S,Caggiano M,Tafuri D,Colao A,Orio F

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Hormonal status and menopause affect human macrophage function and cardiometabolic risk. In polycystic ovary syndrome (PCOS) patients the cardiometabolic risk increases through mechanisms that are largely unknown. We tested the hypotheses that macrophage activation is influenced by menstrual cycle and that ovar...

journal_title：Endocrine

authors： Tedesco S,Adorni MP,Ronda N,Cappellari R,Mioni R,Barbot M,Pinelli S,Plebani M,Bolego C,Scaroni C,Bernini F,Fadini GP,Cignarella A

更新日期：2019-11-01 00:00:00

abstract：:The cytoplasmic Ca2+ concentration ([Ca2+]i) was measured with dual wavelength fluorometry in glucagon-producing mouse pancreatic alpha-cells loaded with the indicator fura-2. Spontaneous rhythmic activity in terms of slow oscillations from a basal level was observed at 3 mM glucose. Like in the insulin-secreting beta...

journal_title：Endocrine

authors： Berts A,Gylfe E,Hellman B

更新日期：1997-02-01 00:00:00