Abstract:
:Asymmetric mRNA expression was found in preoptic anterior and hypothalamic anterior areas of the two estrogen receptor isoforms and the gonadotropin-releasing hormone. On the right side of these areas, estrogen receptor alpha mRNA expression reached its peak on estrus day, while on the left side the peak was reached on proestrus day. Estrogen receptor beta mRNA expression peaked on both sides on the same day, diestrous-2 day, but at different hours, showing a sustained expression for the next measured hour on the left side, while peaking and dropping abruptly on the right side. Gonadotropin-releasing hormone also peaked on both sides on diestrous-2 day, being the left side peak expression significantly lower than the peak expression at the right side. The side expression differences suggest that different sides of the before mentioned areas may play different roles of endocrine reproductive functions, while differences of expression at different times may suggest interaction between sides for the same functions.
journal_name
Endocrinejournal_title
Endocrineauthors
Arteaga-López PR,Domínguez R,Cerbón MA,Mendoza-Rodríguez CA,Cruz MEdoi
10.1385/ENDO:21:3:251subject
Has Abstractpub_date
2003-08-01 00:00:00pages
251-60issue
3eissn
1355-008Xissn
1559-0100pii
ENDO:21:3:251journal_volume
21pub_type
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