Melatonin and Parkinson's disease.

abstract：:We wanted to evaluate the cutaneous synthesis of 25OHD and cholecalciferol after one whole-body exposure to ultraviolet radiation type B (UVB) in a randomized setup. Healthy volunteers were randomized to one whole-body exposure in a commercial tanning bed with UVB emission (UVB/UVA ratio 1.8-2.0%) or an identical plac...

journal_title：Endocrine

authors： Langdahl JH,Schierbeck LL,Bang UC,Jensen JE

更新日期：2012-10-01 00:00:00

abstract：:Tumor suppressor p53 is a transcriptional factor that determines cell fate in response to multiple stressors, such as oxidative stress and endoplasmic reticulum stress, in the majority of cells. However, its role in pancreatic beta cells is not well documented. Our previous research has revealed that glycation-serum (...

journal_title：Endocrine

authors： Li Y,Zhang T,Huang Q,Sun Y,Chang X,Zhang H,Zhu Y,Han X

更新日期：2016-11-01 00:00:00

abstract：:We investigated whether 1,25-dihydroxy-vitamin D3 (1,25(OH)2D3) could improve early diabetic nephropathy through the DNA-damage-inducible transcript 4/tuberous sclerosis 2/mammalian target of rapamycin pathway. Rat mesangial cells were cultured in media containing normal glucose or high glucose and were treated with o...

journal_title：Endocrine

authors： Wang H,Wang J,Qu H,Wei H,Ji B,Yang Z,Wu J,He Q,Luo Y,Liu D,Duan Y,Liu F,Deng H

更新日期：2016-11-01 00:00:00

abstract：:Plasma levels for insulin-like growth factor-I (IGF-I) steadily increase in female rats between 20 and 40 d of life, and this increase is intimately related to the wellknown growth spurt occurring at this age. Since specific actions of IGF-I related to sexual function have been described at the ovarian and hypothalami...

journal_title：Endocrine

authors： Gruaz NM,d'Allèves V,Charnay Y,Skottner A,Ekvärn S,Fryklund L,Aubert ML

更新日期：1997-02-01 00:00:00

abstract：:The role of membrane-associated tubulin in TRH receptor-G protein coupling was investigated with the use of compounds that influence tubulin function. TRH-stimulated G protein GTPase activity in GH(3) cell membranes was used to determine receptor-G protein coupling. TRH-stimulated GTPase activity was abolished by G(qα...

journal_title：Endocrine

authors： Ravindra R,Forman LJ,Patel SA

更新日期：1996-02-01 00:00:00

abstract：PURPOSE:Long-standing hypoglycemia can cause cognitive impairment, and whether recurrent severe hypoglycemia impacts cognitive function in patients with insulinoma has not been studied. This study focused on exploring the cognitive function in patients with insulinoma. METHODS:A prospective study was conducted to asse...

journal_title：Endocrine

authors： Dai H,Chen H,Hong X,Han X,Xu Q,Pang H,Yuan J,Wang X,Xu P,Jiang J,Jiang R,Zhuang Z,Zhao Y,Wu W

更新日期：2019-09-01 00:00:00

abstract：:To determine whether the administration of small amounts of glucose through an oral spray device (GSD) facilitates weight loss in overweight/obese subjects involved in a lifestyle modification programme. We randomly assigned 56 overweight/obese subjects to either the treatment group (n = 32) or the control group (n = ...

journal_title：Endocrine

authors： Khazrai YM,Maddaloni E,Altomare M,Cacciapaglia F,Pozzilli P

更新日期：2014-03-01 00:00:00

abstract：:Thioredoxin-interacting protein (TXNIP) is a known important regulatory protein of islet β-cell biology and function, but the detailed mechanism is not clear. Autophagy plays a pivotal role in maintaining cellular homoeostasis. This study aimed to elucidate the influence of TXNIP on the autophagy of β-cell. In this st...

journal_title：Endocrine

authors： Deng W,Li Y,Ren Z,He Q,Jia Y,Liu Y,Zhang W,Gan X,Liu D

更新日期：2020-12-01 00:00:00

abstract：:Extrinsic and intrinsic signaling gradients determine expression patterns of pituitary-specific factors in the developing anterior pituitary gland. The temporal and spatial relations of these developmental factors are required for the determination of each of the pituitary cell lineages. Rpx is required for early diff...

journal_title：Endocrine

authors： Cohen LE

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Several conditions can modify the intestinal absorption of levothyroxine tablets, with potential consequences on their therapeutic effect. Pre-dosed ampoules and oral drops have been recently made available to overcome this limitation. AIMS:To describe the pattern of use of different formulations of levothy...

journal_title：Endocrine

authors： Ferrara R,Ientile V,Arcoraci V,Ferrajolo C,Piccinni C,Fontana A,Benvenga S,Trifirò G

更新日期：2017-10-01 00:00:00

abstract：:The goal of the present study was to investigate whether p53 antibodies (Abs) could be a relevant marker for papillary thyroid carcinoma (PTC). Three types of enzyme-linked immunosorbent assay (ELISA) methods were developed for the detection of p53 Abs, including p53-ELISA, phage-SS-ELISA, and phage-SP-ELISA. A total ...

journal_title：Endocrine

authors： Pan P,Han X,Li F,Fu Q,Gao X,Sun H,Wang L

更新日期：2014-11-01 00:00:00

abstract：:In glucocorticoid-induced osteoporosis (GIO), both bone formation and resorption are altered, however, with a relative prevalence of resorption, consistent with the positive results that have been reported with bisphosphonate treatment. Many studies have investigated the effect of bisphosphonates (BPs), a widely used ...

journal_title：Endocrine

authors： Rossini M,Orsolini G,Viapiana O,Adami S,Gatti D

更新日期：2015-08-01 00:00:00

abstract：:To investigate the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey. Seventy-six patients with CPHD were included in this study. Based on clinical, hormonal, and neuro-radiological data, relevant transcription factor genes were evaluated...

journal_title：Endocrine

authors： Baş F,Uyguner ZO,Darendeliler F,Aycan Z,Çetinkaya E,Berberoğlu M,Şiklar Z,Öcal G,Darcan Ş,Gökşen D,Topaloğlu AK,Yüksel B,Özbek MN,Ercan O,Evliyaoğlu O,Çetinkaya S,Şen Y,Atabek E,Toksoy G,Aydin BK,Bundak R

更新日期：2015-06-01 00:00:00

abstract：:Ovulation and conversion of the follicle into the corpus luteum involve remarkable changes in vascular permeability and neovascularization of the luteinizing granulosa layer. To evaluate the importance of these vascular events in follicle rupture and luteal development, sequential experiments were designed in which ve...

journal_title：Endocrine

authors： Hazzard TM,Rohan RM,Molskness TA,Fanton JW,D'Amato RJ,Stouffer RL

更新日期：2002-04-01 00:00:00

abstract：:The objective was to determine molecular genetic analysis of the TPO gene in Turkish children with iodide organification defect (IOD). Patients with a diagnosis of primary hypothyroidism were evaluated. Subjects having a definite diagnosis of autoimmune thyroiditis, thyroid gland dysplasia and, or iodine deficiency we...

journal_title：Endocrine

authors： Turkkahraman D,Alper OM,Pehlivanoglu S,Aydin F,Yildiz A,Luleci G,Akcurin S,Bircan I

更新日期：2010-02-01 00:00:00

abstract：:Circadian rhythmicity is affected in obese subjects. This article analyzes the effect of a high-fat diet (35% fat) on 24-h changes circulating prolactin, luteinizing hormone (LH), testosterone, corticosterone, thyroid-stimulating hormone (TSH) and glucose, and pineal melatonin content, in rats. When body weight of rat...

journal_title：Endocrine

authors： Cano P,Jiménez-Ortega V,Larrad A,Reyes Toso CF,Cardinali DP,Esquifino AI

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:Acromegaly is a systemic metabolic disease. Growth hormone (GH) have a significant impact on adipose tissue (AT). A huge reduction of serum GH after surgical treatment may cause substantial AT redistribution. The objective of this study was to illustrate the dynamic changes in distribution of facial and abdomin...

journal_title：Endocrine

authors： Xie T,Ding H,Xia M,Zhang X,Sun W,Liu T,Gu Y,Sun C,Hu F

更新日期：2018-12-01 00:00:00

abstract：:Factors affecting longevity are complex and poorly understood. We have recently found that Ames dwarf mice (df/df), which are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone, live significantly longer than their normal siblings whereas transgenic mice that overexpress GH exhibit reduced li...

journal_title：Endocrine

authors： Brown-Borg HM,Bode AM,Bartke A

更新日期：1999-08-01 00:00:00

abstract：UNLABELLED:Brain-derived neurotrophic factor (BDNF) has emerged as a new element related with insulin resistance and obesity. OBJECTIVE:To evaluate the effect of a 3-month reduced-calorie diet (RCD) on serum BDNF concentrations in overweight and obese subjects. SUBJECTS:Seventeen healthy overweight and obese subjects...

journal_title：Endocrine

authors： Araya AV,Orellana X,Espinoza J

更新日期：2008-06-01 00:00:00

abstract：:Both osteoporosis and cardiovascular disease (CVD) are major public health problems leading to increased morbidity and mortality. Although traditionally viewed as separate disease entities that increase in prevalence with aging, accumulating evidence indicates that there are similar pathophysiological mechanisms under...

journal_title：Endocrine

authors： McFarlane SI,Muniyappa R,Shin JJ,Bahtiyar G,Sowers JR

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effect of combining human parathyroid hormone (1-34) (PTH1-34; PTH) and menaquinone-4 (MK-4) on calvarial bone defect repair in osteopenic rats. METHODS:Fourteen week olds were subject to craniotomy for the establishment of osteopenic animal models fed through a chroni...

journal_title：Endocrine

authors： Weng SJ,Xie ZJ,Wu ZY,Yan DY,Tang JH,Shen ZJ,Li H,Bai BL,Boodhun V,Eric Dong XD,Yang L

更新日期：2019-02-01 00:00:00

abstract：:To explore the regulation of follistatin gene expression, porcine granulosa cells were incubated with the translational inhibitor, cycloheximide (CHX), for periods from 6-24 h. This resulted in a 3 to 10-fold increase in follistatin mRNA accumulation compared to vehicle treated control cultures. At 20 h, CHX augmented...

journal_title：Endocrine

authors： Lindsell CE,Misra V,Murphy BD

更新日期：1995-08-01 00:00:00

abstract：:Effects of hypothyroidism on the glucose and insulin levels are controversial, and its impact on the Langerhans islet morphology of adult subjects has been poorly addressed. In spite of hypothyroidism and diabetes mellitus are more frequent in females than in males, most studies using animal models have been done in m...

journal_title：Endocrine

authors： Rodríguez-Castelán J,Nicolás L,Morimoto S,Cuevas E

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Surgical procedures are associated with activation of the hypothalamic-pituitary-adrenal axis (HPA). Studies examining HPA dynamics peri-operatively are limited and the modulating influence of peri-operatively administered glucocorticoids on that is not well established. This investigation examined alteratio...

journal_title：Endocrine

authors： El-Sibai K,Rajpal A,Al-Aridi R,Selman WR,Arafah BM

更新日期：2017-10-01 00:00:00

abstract：:Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are synthesized and released from adrenal cells. Therefore, the effects of TNF-alpha and IL-6 on cortisol release from bovine zona fasciculata (ZF) cells were investigated. IL-6 (10-1000 pg/mL) significantly increased basal and adrenocorticotropic hormon...

journal_title：Endocrine

authors： Barney M,Call GB,McIlmoil CJ,Husein OF,Adams A,Balls AG,Oliveira GK,Miner EC,Richards TA,Crawford BK,Heckmann RA,Bell JD,Judd AM

更新日期：2000-12-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) acts as a nutrient-dependent insulin-releasing agent, and its insulinotropic action is enhanced by nutrient secretagogues, such as the dimethyl ester of succinic acid (SAD). In the present study, a primed constant infusion of SAD (0.5 micromol followed by 0.25 micromol/min both per g of...

journal_title：Endocrine

authors： Cancelas J,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：2001-08-01 00:00:00

abstract：:External ATP is believed to initiate and propagate Ca(2+) signals co-ordinating the insulin release pulses within and among the different islets in the pancreas. The possibility that islet endothelial cells participate in this process was evaluated by comparing the effects on [Ca(2+)](i) of purinoceptor activation in ...

journal_title：Endocrine

authors： Hellman B,Jansson L,Dansk H,Grapengiesser E

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Bilateral inferior petrosal sinus sampling (BIPSS) is useful for differential diagnosis of adult Cushing's disease (CD) but may not be so reliable in pediatric cases. The purpose of this study was to evaluate the sensitivity of BIPSS before and after desmopressin stimulation in pediatric CD, and to explore rela...

journal_title：Endocrine

authors： Chen S,Chen K,Lu L,Zhang X,Tong A,Pan H,Zhu H,Lu Z

更新日期：2019-03-01 00:00:00

abstract：:Core needle biopsy (CNB) has been recently described as an accurate second-line test in thyroid inconclusive cytology (FNA). Here we retrospectively investigated the potential improvement given by Galectin-3, Cytokeratin-19, and HBME-1 on the accuracy of CNB in thyroid nodules with prior indeterminate FNA report. The ...

journal_title：Endocrine

authors： Trimboli P,Guidobaldi L,Amendola S,Nasrollah N,Romanelli F,Attanasio D,Ramacciato G,Saggiorato E,Valabrega S,Crescenzi A

更新日期：2016-04-01 00:00:00

abstract：:Testosterone deficiency is commonly associated with obesity, metabolic syndrome, type 2 diabetes and their clinical consequences-hepatic steatosis and atherosclerosis. The testicular feminised mouse (non-functional androgen receptor and low testosterone) develops fatty liver and aortic lipid streaks on a high-fat diet...

journal_title：Endocrine

authors： Kelly DM,Akhtar S,Sellers DJ,Muraleedharan V,Channer KS,Jones TH

更新日期：2016-11-01 00:00:00