Stimulation by interleukin-6 and inhibition by tumor necrosis factor of cortisol release from bovine adrenal zona fasciculata cells through their receptors.

abstract：PURPOSE:PTEN and KLLN are two tumor suppressor genes located in 10q23, share a bidirectional promoter and have roles in carcinogenesis. Formerly, the role of PTEN mutations and KLLN epimutations were identified in incidence of thyroid lesions in individuals with Cowden syndrome, a rare autosomal dominant inherited diso...

journal_title：Endocrine

authors： Razavi SA,Modarressi MH,Yaghmaei P,Tavangar SM,Hedayati M

更新日期：2017-09-01 00:00:00

abstract：:Thymic carcinoid is an important component of the tumor spectrum causing Ectopic ACTH Syndrome (EAS) and usually carries a poor prognosis. Efforts have been focused on exploring the mechanism of the excessive ACTH production in non-pituitary tumors, whereas few studies have reported the molecular events underlying the...

journal_title：Endocrine

authors： Liu RX,Wang WQ,Ye L,Bi YF,Fang H,Cui B,Zhou WW,Dai M,Zhang J,Li XY,Ning G

更新日期：2010-08-01 00:00:00

abstract：:Oxytocin (OT) and arginine-vasopressin (AVP) are two major neurohypophysary nonapeptides that have impor-tant roles during pregnancy and labor. Using the expiant model at term, we have examined the effect of physiologic concentrations of both nonapeptides on placental hormone secretion. We found that OT had a dose-dep...

journal_title：Endocrine

authors： Barnea ER,Maruo T,Schurtz-Swirsky R

更新日期：1995-04-01 00:00:00

abstract：:Tumor suppressor p53 is a transcriptional factor that determines cell fate in response to multiple stressors, such as oxidative stress and endoplasmic reticulum stress, in the majority of cells. However, its role in pancreatic beta cells is not well documented. Our previous research has revealed that glycation-serum (...

journal_title：Endocrine

authors： Li Y,Zhang T,Huang Q,Sun Y,Chang X,Zhang H,Zhu Y,Han X

更新日期：2016-11-01 00:00:00

abstract：:Regulation of energy homeostasis is tightly controlled by the central nervous system (CNS). Several key areas such as the hypothalamus and brainstem receive and integrate signals conveying energy status from the periphery, such as leptin, thyroid hormones, and insulin, ultimately leading to modulation of food intake, ...

journal_title：Endocrine

authors： Seoane-Collazo P,Fernø J,Gonzalez F,Diéguez C,Leis R,Nogueiras R,López M

更新日期：2015-11-01 00:00:00

abstract：:In this study we analyzed whether corticosterone synthesis is involved in the regulation of adrenal gland type II deiodinase (AG-D2) activity during acute cold exposure. Two well-known inhibitors of steroidogenesis, aminoglutethimide (AGT) and metyrapone (MTP), were administered to male Wistar rats maintained either a...

journal_title：Endocrine

authors： Anguiano B,Valverde C

更新日期：2001-06-01 00:00:00

abstract：INTRODUCTION:Primary autoimmune hypophysitis (PAHs) is a rare inflammatory disease of the pituitary gland. Although largely investigated, the pathogenesis of PAH is not completely clarified. We aimed to investigate the immune response in PAHs. MATERIAL AND METHODS:Serum anti-pituitary and anti-hypothalamus antibodies ...

journal_title：Endocrine

authors： Chiloiro S,Giampietro A,Angelini F,Arena V,Stigliano E,Tartaglione T,Mattogno PP,D'Alessandris QG,Lauretti L,Pontecorvi A,De Marinis L,Bianchi A

更新日期：2021-01-23 00:00:00

abstract：:Hypoxia is a common neonatal stress that induces insulin resistance and a decrease in body weight gain. Dexamethasone is often used to treat neonatal cardiopulmonary disease, and also leads to insulin resistance and a decrease in body weight gain. The current study addressed the hypothesis that serum concentrations of...

journal_title：Endocrine

authors： Raff H,Bruder ED

更新日期：2006-04-01 00:00:00

abstract：:The anterior pituitary gland of the Siberian hamster contains high concentrations of tachykinins compared to other laboratory rodents. In this investigation we studied the relative quantities of neurokinin A (NKA), neuropeptide gamma (NPG), and neuropeptide K (NPK) present in extracts of anterior pituitaries from this...

journal_title：Endocrine

authors： Debeljuk L,Rao JN,Bartke A

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Growth hormone deficiency (GHD) is a condition associated with increased cardiovascular risk and insulin-resistance. Oxidative stress (OS) could be a mechanism underlying both these phenomena. In order to investigate plasma antioxidant defenses in such condition, we evaluated adults with GHD, compar...

journal_title：Endocrine

authors： Mancini A,Di Segni C,Bruno C,Olivieri G,Guidi F,Silvestrini A,Meucci E,Orlando P,Silvestri S,Tiano L,Pontecorvi A

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:Bisphenol-A (BPA) is an endocrine-disrupting chemical that may affect the hormones and their receptors. The aim of this study is to determine whether BPA has an effect on the development of nonfunctional adrenal incidentaloma (NFAI). METHODS:Fifty patients who were admitted to endocrinology outpatient clinics ...

journal_title：Endocrine

authors： Eker F,Gungunes A,Durmaz S,Kisa U,Celik ZR

更新日期：2020-09-23 00:00:00

abstract：:Many aspects of tuberoinfundibular dopaminergic neuronal function are increased by elevated prolactin (PRL) levels, including the activity of tyrosine hydroxylase, the rate-limiting enzyme in the biosynthesis of dopamine. This study evaluated the roles of calmodulin, cyclic nucleotide-dependent protein kinase, and cal...

journal_title：Endocrine

authors： Arbogast LA

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:Parathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited number of samples. The aim of the present study was to verify a group of mi...

journal_title：Endocrine

authors： Hu Y,Zhang X,Cui M,Su Z,Wang M,Liao Q,Zhao Y

更新日期：2018-05-01 00:00:00

abstract：:Strict glucose control is a well-proven therapeutic approach for peripheral neuropathies in patients with diabetes. Alpha lipoic acid (ALA) has also been accepted as a therapeutic agent for diabetic peripheral neuropathy (DPN) in the respect of pathogenesis. However, the potential of ALA as a treatment for DPN in comp...

journal_title：Endocrine

authors： Lee KA,Lee NY,Park TS,Jin HY

更新日期：2018-07-01 00:00:00

abstract：:Altered bone micro-architecture is an important factor in accounting for fragility fractures. Until recently, it has not been possible to gain information about skeletal microstructure in a way that is clinically feasible. Bone biopsy is essentially a research tool. High-resolution peripheral Quantitative Computed Tom...

journal_title：Endocrine

authors： Ulivieri FM,Silva BC,Sardanelli F,Hans D,Bilezikian JP,Caudarella R

更新日期：2014-11-01 00:00:00

abstract：:Follicle-stimulating hormone is synthesized and secreted as a mixture of heterogeneous isoforms that differ from each other in carbohydrate structure, biological potency, and plasma half-life. The relative abundance of the FSH isoforms will depend on the endocrine status of the donor at the time of sample collection. ...

journal_title：Endocrine

authors： Olivares A,Söderlund D,Castro-Fernández C,Zariñán T,Zambrano E,Méndez JP,Ulloa-Aguirre A

更新日期：2004-03-01 00:00:00

abstract：:Ghrelin is an endogenous growth hormone secretagogue (GHS) causing release of GH from pituitary somatotropes through the GHS receptor. Secretion of GH is linked directly to intracellular free Ca2+ concentration ([Ca2+]i), which is determined by Ca2+ influx and release from intracellular Ca2+ storage sites. Ca2+ influx...

journal_title：Endocrine

authors： Han X,Zhu Y,Zhao Y,Chen C

更新日期：2011-10-01 00:00:00

abstract：:Acromegaly is a debilitating disease usually caused by a growth-hormone secreting pituitary adenoma. Therapeutic goals include improvement of symptoms, reduction in tumor mass, biochemical normalization, and preservation of pituitary function. Treatment options include transsphenoidal surgery, radiation, and pharmacot...

journal_title：Endocrine

authors： Danoff A,Kleinberg D

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:A promising radiopharmaceutical (99m)Tc-HYNIC-TOC ((99m)Tc-HYNIC-Octreotide) can be applied for somatostatin receptor scintigraphy with the potential to replace Indium-111 labeled somatostatin analogus. Here we evaluate whether orbital (99m)Tc-HYNIC-TOC scintigraphy can be used as a Graves' ophthalmopathy (GO...

journal_title：Endocrine

authors： Sun H,Jiang XF,Wang S,Chen HY,Sun J,Li PY,Ning G,Zhao YJ

更新日期：2007-06-01 00:00:00

abstract：:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are relatively rare and heterogenous malignancies. Recent advances in histopathological classification according to the anatomical site of origin, proliferation rate, and extend of the disease have created a valid and powerful tool for the prognostic stratificati...

journal_title：Endocrine

authors： Alexandraki KI,Kaltsas G

更新日期：2012-02-01 00:00:00

abstract：:In order to identify GH target cells in human tissues, we investigated the celiuiar distribution of human GH receptor (GHR) messenger RNA. This was performed byin situ hybridization and Northern blot hybridization using complementary radioactive DNA probe encoding part of the extracellular domain of the GHR. Several t...

journal_title：Endocrine

authors： Mertani HC,Delehaye-Zervas MC,Martini JF,Postel-Vinay MC,Morel G

更新日期：1995-02-01 00:00:00

abstract：:To determine whether murine mammary growth is modulated by local insulin-like growth factor-1 (IGF-1) production, expression of recombinant IGF-1 was directed to the mammary glands of transgenic mice using an ovine prepro IGF-1 cDNA under control of the mouse mammary tumor virus-long terminal repeat (MMTV-LTR) promote...

journal_title：Endocrine

authors： Weber MS,Boyle PL,Corl BA,Wong EA,Gwazdauskas FC,Akers RM

更新日期：1998-06-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a rare disease in which the most common endocrine manifestation is diabetes insipidus (DI). Data on anterior pituitary function in patients with LCH are limited. Thus, the present study investigated anterior pituitary function in LCH patients with DI via the evaluation of clinica...

journal_title：Endocrine

authors： Kurtulmus N,Mert M,Tanakol R,Yarman S

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:Risk of cardiovascular disease (CVD) is increased in Graves' disease (GD). CVD is predicted by increased pulse wave velocity (PWV) and blood pressure (BP). GD and these risk factors are all associated with lower levels of vitamin D. We aimed to assess the effect of supplemental vitamin D on PWV and BP in GD. M...

journal_title：Endocrine

authors： Grove-Laugesen D,Malmstroem S,Ebbehoj E,Riis AL,Watt T,Hansen KW,Rejnmark L

更新日期：2019-11-01 00:00:00

abstract：:Medullary thyroid carcinoma (MTC) is a rare tumour which frequently occurs in the context of the multiple endocrine neoplasia syndromes, where it coexists with other usually benign tumours. The clinical picture varies and distant metastases are frequently present at diagnosis. Calcitonin levels are elevated in the pre...

journal_title：Endocrine

authors： Alevizaki M,Kyratzoglou E,Bamias A,Tzanela M,Dimopoulos MA,Saltiki K

更新日期：2013-12-01 00:00:00

abstract：:The aim is to study the association of estrogen receptor α (ERα) and estrogen receptor β (ERβ) gene polymorphisms and diplotypes with ovarian response to follicle-stimulating hormone (FSH) stimulation and the hormone levels [FSH, luteinizing hormone (LH), E2] at the third day of the menstrual cycle. Three hundred wome...

journal_title：Endocrine

authors： Lazaros L,Pamporaki C,Vlahos N,Takenaka A,Kitsou C,Kosmas I,Sofikitis N,Stefos T,Zikopoulos K,Hatzi E,Georgiou I

更新日期：2014-12-01 00:00:00

abstract：:Our aim was to assess short-term natural course of hypogonadism diagnosed during hospitalization for acute disease in aged male patients after discharge. A group of 43 hypogonadal males, aged 86.7±5.7 year, was studied. Serum concentrations of testosterone (T) and gonadotropins (follicle-stimulating hormone, FSH, and ...

journal_title：Endocrine

authors： Iglesias P,Prado F,Muñoz A,Guerrero MT,Macías MC,Ridruejo E,Tajada P,García-Arévalo C,Díez JJ

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Low mineral mass and reduced bone strength with increased fracture risk are the main causes of morbidity in Thalassemia Major (TM). The pathogenesis is multifactorial and includes ineffective erythropoiesis with medullary expansion, multiple endocrine dysfunctions, direct iron bone deposition, deferoxamine-i...

journal_title：Endocrine

authors： Pellegrino F,Zatelli MC,Bondanelli M,Carnevale A,Cittanti C,Fortini M,Gamberini MR,Giganti M,Ambrosio MR

更新日期：2019-09-01 00:00:00

abstract：:Oestradiol (E(2)) alters lymphocyte functionin vitro including T cell DNA synthesis and B cell immunoglobulin production in human tonsillar, splenic and peripheral blood cells. We have investigated whether one mechanism for this effect is that E(2) modifies the expression of IL-2, IL-6 and IFN-γ mRNA in human tonsilla...

journal_title：Endocrine

authors： Evagelatou M,Farrant J

更新日期：1995-11-01 00:00:00

abstract：:Since the 1990's cabergoline has been the treatment of choice in prolactinoma, as it permits rapid and effective hormonal and tumor control in most cases. Evidence of cardiac valvulopathy was demonstrated in Parkinson's disease patients treated with dopamine agonists. Retrospective studies in prolactinoma patients tre...

journal_title：Endocrine

authors： Vroonen L,Lancellotti P,Garcia MT,Dulgheru R,Rubio-Almanza M,Maiga I,Magne J,Petrossians P,Auriemma R,Daly AF,Beckers A

更新日期：2017-01-01 00:00:00