Ghrelin reduces voltage-gated calcium currents in GH₃ cells via cyclic GMP pathways.

abstract：:Environmental factors have been implicated in the development of autoimmune thyroid disease (AITD). Anti-Saccaromyces Cerevisiae Antibodies (ASCA) were shown to be elevated in several autoimmune diseases. The aim of the study was to determine ASCA levels and their relationship with thyroid autoantibodies in patients w...

journal_title：Endocrine

authors： Yazıcı D,Aydın SZ,Yavuz D,Tarçın O,Deyneli O,Direskeneli H,Akalın S

更新日期：2010-10-01 00:00:00

abstract：:We wanted to evaluate the cutaneous synthesis of 25OHD and cholecalciferol after one whole-body exposure to ultraviolet radiation type B (UVB) in a randomized setup. Healthy volunteers were randomized to one whole-body exposure in a commercial tanning bed with UVB emission (UVB/UVA ratio 1.8-2.0%) or an identical plac...

journal_title：Endocrine

authors： Langdahl JH,Schierbeck LL,Bang UC,Jensen JE

更新日期：2012-10-01 00:00:00

abstract：:To investigate the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey. Seventy-six patients with CPHD were included in this study. Based on clinical, hormonal, and neuro-radiological data, relevant transcription factor genes were evaluated...

journal_title：Endocrine

authors： Baş F,Uyguner ZO,Darendeliler F,Aycan Z,Çetinkaya E,Berberoğlu M,Şiklar Z,Öcal G,Darcan Ş,Gökşen D,Topaloğlu AK,Yüksel B,Özbek MN,Ercan O,Evliyaoğlu O,Çetinkaya S,Şen Y,Atabek E,Toksoy G,Aydin BK,Bundak R

更新日期：2015-06-01 00:00:00

abstract：:This study was performed to ascertain whether a relationship exists between thyroid function and blood pressure in school-aged Chinese subjects without overt thyroid disease. A cross-sectional survey of 880 subjects (541 females and 339 males) aged 7-18 years in Bengbu, Anhui province was conducted. The investigation,...

journal_title：Endocrine

authors： Chen H,Xi Q,Zhang H,Song B,Liu X,Mao X,Li J,Shen H,Tang W,Zhang J,Wang Z,Duan Y,Liu C

更新日期：2012-02-01 00:00:00

abstract：:Regular endurance exercise promotes metabolic and oxidative changes in skeletal muscle. Overexpression of interleukin-15 (IL-15) in mice exerts similar metabolic changes in muscle as seen with endurance exercise. Muscular IL-15 production has been shown to increase in mice after weeks of regular endurance running. Wit...

journal_title：Endocrine

authors： Rinnov A,Yfanti C,Nielsen S,Akerström TC,Peijs L,Zankari A,Fischer CP,Pedersen BK

更新日期：2014-03-01 00:00:00

abstract：:Cytoplasmic calcium ([Ca(2+)](i)) changes evoked by adenosine 5(1)-triphosphate (ATP) were recorded in cultured individual Leydig cells within 10-18 h after cell dispersion. [Ca(2+)](i) was monitored using Fura-2AM loaded cells with a digital ratio imaging system. Five micromolars ATP induced biphasic [Ca(2+)](i) resp...

journal_title：Endocrine

authors： Pérez-Armendariz EM,Nadal A,Fuentes E,Spray DC

更新日期：1996-06-01 00:00:00

abstract：:Progesterone is a steroid which regulates neural function, thereby modulating neurotransmission, cell survival, and behavior. Previous studies by our group have shown that chronic administration of low doses of progesterone in diestrus II female rats has an antidepressant-like effect in the forced swimming test (FST)....

journal_title：Endocrine

authors： Arbo BD,Andrade S,Osterkamp G,Gomez R,Ribeiro MF

更新日期：2014-08-01 00:00:00

abstract：:External ATP is believed to initiate and propagate Ca(2+) signals co-ordinating the insulin release pulses within and among the different islets in the pancreas. The possibility that islet endothelial cells participate in this process was evaluated by comparing the effects on [Ca(2+)](i) of purinoceptor activation in ...

journal_title：Endocrine

authors： Hellman B,Jansson L,Dansk H,Grapengiesser E

更新日期：2007-08-01 00:00:00

abstract：:This study examined the interrelationship between transforming growth factor-beta1 (TGF-beta1) and 17beta-estradiol (E2) in the regulation of growth plate chondrocytes. To determine whether TGF-beta1 modulates chondrocyte response to E2, we used cells isolated from the resting zone (RC) and growth zone (GC) of costoch...

journal_title：Endocrine

authors： Nasatzky E,Grinfeld D,Boyan BD,Dean DD,Ornoy A,Schwartz Z

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:This study aimed to analyze the clinical and genetic characteristics of Chinese children with congenital hyperinsulinemia (CHI) that is spontaneously relieved. METHODS:The patient group comprised 200 children with CHI that were treated at the Beijing Children's Hospital from January 2006 to December 2018. Th...

journal_title：Endocrine

authors： Xu ZD,Hui PP,Zhang W,Zeng Q,Zhang L,Liu M,Yan J,Wu YJ,Sang YM

更新日期：2021-01-27 00:00:00

abstract：:PET/CT with (18)F-fluorodeoxyglucose (FDG) or using different radiocompounds has proven accuracy for detection of adrenal metastases in patients undergoing cancer staging. It can assist the diagnostic work-up in oncology patients by identifying distant metastases to the adrenal(s) and defining oligometastatic disease ...

journal_title：Endocrine

authors： Kandathil A,Wong KK,Wale DJ,Zatelli MC,Maffione AM,Gross MD,Rubello D

更新日期：2015-05-01 00:00:00

abstract：:The application of a hemolytic plaque assay to antigen-secreting endocrine cells has brought about great advances in the study of regulation of hormone secretion. The reverse hemolytic plaque assay (RHPA) has enabled quantitation of secretion at the single cell level with simultaneous analysis of the population respon...

journal_title：Endocrine

authors： Gregerson KA

更新日期：1995-05-01 00:00:00

abstract：:Leptin shows pleiotropic effects in organisms including an important role in the regulation of glucose homeostasis. Elevated serum leptin, particularly in obese individuals, is a warning sign of energy imbalance, hyperinsulinemia, insulin resistance and other metabolic risk factors that are strongly associated with ty...

journal_title：Endocrine

authors： Pliszka M,Oleszczak B,Szablewski L

更新日期：2015-05-01 00:00:00

abstract：:The effect of stress on serum corticosteroid-binding globulin (CBG) was studied in adult male Sprague-Dawley rats. CBG was measured either by a homologous radioimmunoassay (RIA) or by a binding assay (BA) using 3H-corticosterone. Exposure of adult male rats to a severe stressor such as immobilization (IMO) for 1 h did...

journal_title：Endocrine

authors： Martí O,Martín M,Gavaldà A,Giralt M,Hidalgo J,Hsu BR,Kuhn RW,Armario A

更新日期：1997-04-01 00:00:00

abstract：:Steroid biosynthesis begins with the enzymatic conversion of cholesterol to pregnenolone. This reaction is catalyzed by the cytochrome P450 side-chain cleavage enzyme (P450scc), which is located on the matrix side of the inner mitochondrial membrane. Although the rate-limiting enzymatic step in steroidogenesis is the ...

journal_title：Endocrine

authors： Sandhoff TW,McLean MP

更新日期：1996-10-01 00:00:00

abstract：:Adult-onset growth-hormone (GH) deficiency (GHD) is a rare disorder, which most commonly results from pituitary or peripituitary tumors and their treatment, and is characterized by alterations in body composition, carbohydrate and lipid metabolism, bone mineral density, cardiovascular risk profile and quality of life,...

journal_title：Endocrine

authors： Ramos-Leví AM,Marazuela M

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Glucose and lipid disturbances, as well as higher tendency to atherosclerosis, are observed in women with polycystic ovary syndrome (PCOS). Thyroid hormones action has long been recognized as an important determinant of glucose and lipid homeostasis. Some studies suggest that even in euthyroid subjects, thyro...

journal_title：Endocrine

authors： Adamska A,Krentowska A,Łebkowska A,Hryniewicka J,Leśniewska M,Adamski M,Kowalska I

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:STEAP4 (six-transmembrane epithelial antigen of the prostate 4) is a metalloreductase that has been shown previously to protect cells from inflammatory damage. Genetic variants in STEAP4 have been associated with numerous metabolic disorders related to obesity, including putative defects in the acute insulin ...

journal_title：Endocrine

authors： Gordon HM,Majithia N,MacDonald PE,Fox JEM,Sharma PR,Byrne FL,Hoehn KL,Evans-Molina C,Langman L,Brayman KL,Nunemaker CS

更新日期：2017-06-01 00:00:00

abstract：:Low 25(OH) vitamin D levels have been associated with several autoimmune diseases and recently with autoimmune thyroid disease (AITD). The aim of the study was to investigate the association of AITD with 25(OH) vitamin D levels in women with polycystic ovary syndrome (PCOS). Fifty women with PCOS were consecutively en...

journal_title：Endocrine

authors： Muscogiuri G,Palomba S,Caggiano M,Tafuri D,Colao A,Orio F

更新日期：2016-08-01 00:00:00

abstract：:Cardiovascular morbidity and mortality are increased in patients with primary hyperparathyroidism (PHPT). We aimed to evaluate left ventricle systolic and diastolic functions with tissue Doppler imaging (TDI) and strain and strain rate echocardiography in patients with PHPT. Thirty-one patients with PHPT and 29 health...

journal_title：Endocrine

authors： Ozdemir D,Kalkan GY,Bayram NA,Onal ED,Ersoy R,Bozkurt E,Cakir B

更新日期：2014-11-01 00:00:00

abstract：:Insulin pumps operate almost universally in the work environment. Tubeless insulin pumps are a relatively recent development for management of insulin-dependent diabetes. This is the first report of location-dependent failure of insulin pump function, possibly due to external interference, occurring only in the settin...

journal_title：Endocrine

authors： Reiher AE,Gallagher TA,Emanuele MA

更新日期：2009-02-01 00:00:00

abstract：:Type 2 diabetes mellitus (DM) carries an increased risk for cardiovascular complications. The brachial-ankle pulse wave velocity (baPWV) is an index for early atherosclerotic changes. Recently, the effect of altered blood rheology on atherosclerosis has received attention. Therefore, this study aimed to examine the as...

journal_title：Endocrine

authors： Li Y,Tian XX,Liu T,Wang RT

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:Bilateral inferior petrosal sinus sampling (BIPSS) is useful for differential diagnosis of adult Cushing's disease (CD) but may not be so reliable in pediatric cases. The purpose of this study was to evaluate the sensitivity of BIPSS before and after desmopressin stimulation in pediatric CD, and to explore rela...

journal_title：Endocrine

authors： Chen S,Chen K,Lu L,Zhang X,Tong A,Pan H,Zhu H,Lu Z

更新日期：2019-03-01 00:00:00

abstract：:Leptin is an important hormone that has potent effects on appetite and body weight. The regulation of leptin gene expression and secretion by corticosteroids and insulin was studied in the rat. Adrenalectomy resulted in a significant reduction in leptin gene expression and secretion. The reduction was corrected by hor...

journal_title：Endocrine

authors： Tan JT,Patel BK,Kaplan LM,Koenig JI,Hooi SC

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:To compare long-term outcomes in patients with adrenal incidentalomas (AIs) with the response to a 1 mg overnight dexamethasone suppression test (DST). METHODS:Consecutive patients with "non-functional" AIs (n = 365) were examined. Patients with overt hormone excess, adrenocortical cancer and known malignancy ...

journal_title：Endocrine

authors： Patrova J,Kjellman M,Wahrenberg H,Falhammar H

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effect of combining human parathyroid hormone (1-34) (PTH1-34; PTH) and menaquinone-4 (MK-4) on calvarial bone defect repair in osteopenic rats. METHODS:Fourteen week olds were subject to craniotomy for the establishment of osteopenic animal models fed through a chroni...

journal_title：Endocrine

authors： Weng SJ,Xie ZJ,Wu ZY,Yan DY,Tang JH,Shen ZJ,Li H,Bai BL,Boodhun V,Eric Dong XD,Yang L

更新日期：2019-02-01 00:00:00

abstract：:Aging is associated with a significant decline in secretion of growth hormone. This in turn leads to reduced circulating IGF-I and changes in IGF-binding proteins. Growth hormone replacement to growth hormone-deficient individuals has been shown to improve quality of life, enhance bone and muscle mass, and reduce card...

journal_title：Endocrine

authors： Rosen CJ

更新日期：2000-04-01 00:00:00

abstract：:Data regarding cardiovascular risk in subjects with non-functioning adrenal adenoma are limited. The objectives of this study are to investigate carotid intima media thickness (IMT) as an indicator of atherosclerosis in subjects with non-functioning adrenal incidentaloma (AI) and to evaluate the factors that could be ...

journal_title：Endocrine

authors： Yener S,Genc S,Akinci B,Secil M,Demir T,Comlekci A,Ertilav S,Yesil S

更新日期：2009-06-01 00:00:00

abstract：UNLABELLED:Gallium-68 somatostatin receptor (SMSR) positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) are valuable diagnostic tools for patients with neuroendocrine tumours (NETs). To date, a meta-analysis about the diagnostic accuracy of these imaging methods is lacking. A...

journal_title：Endocrine

authors： Treglia G,Castaldi P,Rindi G,Giordano A,Rufini V

更新日期：2012-08-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) patients treated with thyroidectomy and radioiodine remnant ablation (RRA) often have detectable TSH-stimulated thyroglobulin (Tg) levels without localizable disease after primary treatment. To assess the value of repeat stimulated Tg assays in these patients' follow-up, we retrospective...

journal_title：Endocrine

authors： Lamartina L,Montesano T,Trulli F,Attard M,Torlontano M,Bruno R,Meringolo D,Monzani F,Tumino S,Ronga G,Maranghi M,Biffoni M,Filetti S,Durante C

更新日期：2016-11-01 00:00:00