Association between whole blood viscosity and arterial stiffness in patients with type 2 diabetes mellitus.

abstract：:Bone metabolism disorder has been identified to play a vital role in the pathogenesis of glucocorticoid-induced osteoporosis (GIOP). The local renin-angiotensin system (RAS) in bone is newly defined to be closely related to the bone metabolism. However, it is unknown whether the local RAS is involved in GIOP. Adult ma...

journal_title：Endocrine

authors： Yongtao Z,Kunzheng W,Jingjing Z,Hu S,Jianqiang K,Ruiyu L,Chunsheng W

更新日期：2014-11-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is significantly affected by environmental regulators impacting on genetic predisposition. Lifestyle changes can significantly modulate the phenotype of this disease. Diet, exercise, smoking, stress, and other factors adversely affect reproductive outcomes in PCOS. These influences can...

journal_title：Endocrine

authors： Norman RJ,Homan G,Moran L,Noakes M

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:to assess bone damage and metabolic abnormalities in patients with Addison's disease given replacement doses of glucocorticoids and mineralocorticoids. METHODS:A total of 87 patients and 81 age-matched and sex-matched healthy controls were studied. The following parameters were measured: urinary cortisol, seru...

journal_title：Endocrine

authors： Camozzi V,Betterle C,Frigo AC,Zaccariotto V,Zaninotto M,De Caneva E,Lucato P,Gomiero W,Garelli S,Sabbadin C,Salvà M,Costa MD,Boscaro M,Luisetto G

更新日期：2018-02-01 00:00:00

abstract：:Homozygous Klotho mutant (kl-/-) mice exhibit a variety of phenotypes resembling human aging, including arteriosclerosis, infertility, skin atrophy, osteoporosis, and short life span. Calcium abnormality, one of the phenotypes in kl-/- mice, is thought to be due to the elevated gene expression of 25-hydroxyvitamin D3 ...

journal_title：Endocrine

authors： Imai M,Ishikawa K,Matsukawa N,Kida I,Ohta J,Ikushima M,Chihara Y,Rui X,Rakugi H,Ogihara T

更新日期：2004-12-01 00:00:00

abstract：:To determine whether murine mammary growth is modulated by local insulin-like growth factor-1 (IGF-1) production, expression of recombinant IGF-1 was directed to the mammary glands of transgenic mice using an ovine prepro IGF-1 cDNA under control of the mouse mammary tumor virus-long terminal repeat (MMTV-LTR) promote...

journal_title：Endocrine

authors： Weber MS,Boyle PL,Corl BA,Wong EA,Gwazdauskas FC,Akers RM

更新日期：1998-06-01 00:00:00

abstract：:For analyzing the changes in immunoglobulins, HSP70, ghrelin levels in blood samples were collected from volunteers vaccinated against swine flu before the vaccinations and on days 3, and 15, and 1 and 2 months after the vaccination in the presence or absence of fever associated with the it. The study included 11 subj...

journal_title：Endocrine

authors： Aydin S,Guven T,Sahin İ,Aksoy A,Kendir Y,İlhan MN,Citil C,Catak Z,Ustun C

更新日期：2012-10-01 00:00:00

abstract：:Tumor suppressor p53 is a transcriptional factor that determines cell fate in response to multiple stressors, such as oxidative stress and endoplasmic reticulum stress, in the majority of cells. However, its role in pancreatic beta cells is not well documented. Our previous research has revealed that glycation-serum (...

journal_title：Endocrine

authors： Li Y,Zhang T,Huang Q,Sun Y,Chang X,Zhang H,Zhu Y,Han X

更新日期：2016-11-01 00:00:00

abstract：:Chronic ethanol exposure causes alterations in biologic membranes of different cell types. (Na + K) adenosine triphosphatase (ATPase), a membrane-bound enzyme inhibited by the acute presence of ethanol, increases its activity in rat kidney after chronic ethanol consumption. The aim of this investigation was to evaluat...

journal_title：Endocrine

authors： Rodrigo R,Rivera G,Lucero Y,Larraguibel C

更新日期：2002-12-01 00:00:00

abstract：:Chronic stress can have a deleterious effect on the re-productive axis that, for females, is manifested in an increased incidence of infertility. However, gonadal steroids may, in turn, affect a female's response to stress as measured by activity within the limbic-hypothalamic-pituitary-adrenal (LHPA) axis. What is no...

journal_title：Endocrine

authors： Wilson ME,Legendre A,Pazol K,Fisher J,Chikazawa K

更新日期：2005-03-01 00:00:00

abstract：:In arthropods, development is controlled by cholesterol-derived steroid hormones: the ecdysteroids. In vertebrates and insects, steroidogenesis is positively regulated and this is mediated by cAMP. In crustaceans, ecdysteroid biosynthesis by steroidogenic organs (Y-organs) is negatively regulated by a neuropeptide, th...

journal_title：Endocrine

authors： Lachaise F,Sommé G,Carpentier G,Granjeon E,Webster S,Baghdassarian D

更新日期：1996-08-01 00:00:00

abstract：:PET/CT with (18)F-fluorodeoxyglucose (FDG) or using different radiocompounds has proven accuracy for detection of adrenal metastases in patients undergoing cancer staging. It can assist the diagnostic work-up in oncology patients by identifying distant metastases to the adrenal(s) and defining oligometastatic disease ...

journal_title：Endocrine

authors： Kandathil A,Wong KK,Wale DJ,Zatelli MC,Maffione AM,Gross MD,Rubello D

更新日期：2015-05-01 00:00:00

abstract：:Hypoxia is well known to decrease appetite and weight gain in growing rats, and to induce weight loss in humans. It has been hypothesized that this is mediated by a change in ghrelin, an orexigenic peptide synthesized and released primarily from the stomach. Rats were exposed to hypoxia for 7 d as neonates (birth-7 d ...

journal_title：Endocrine

authors： Raff H

更新日期：2003-07-01 00:00:00

abstract：:In randomized controlled trials (RCTs), more intensive glucose control in patients with type 2 diabetes leads to a modest (9%) reduction in major cardiovascular events (MACE), associated with a 20% reduction of kidney events and 13% reduction of eye events. The FDA issued guidance in 2008 led to the conduct of numerou...

journal_title：Endocrine

authors： Giugliano D,Maiorino MI,Bellastella G,Esposito K

更新日期：2018-05-01 00:00:00

abstract：:The objective was to determine molecular genetic analysis of the TPO gene in Turkish children with iodide organification defect (IOD). Patients with a diagnosis of primary hypothyroidism were evaluated. Subjects having a definite diagnosis of autoimmune thyroiditis, thyroid gland dysplasia and, or iodine deficiency we...

journal_title：Endocrine

authors： Turkkahraman D,Alper OM,Pehlivanoglu S,Aydin F,Yildiz A,Luleci G,Akcurin S,Bircan I

更新日期：2010-02-01 00:00:00

abstract：:Adrenal crises are life-threatening complications of adrenal insufficiency. These events have an estimated incidence of between 5 and 10  adrenal crises/100 patient years and are responsible for some of the increased morbidity and excess mortality experienced by patients with adrenal insufficiency. Treatment involves ...

journal_title：Endocrine

authors： Rushworth RL,Torpy DJ,Falhammar H

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Risk of cardiovascular disease (CVD) is increased in Graves' disease (GD). CVD is predicted by increased pulse wave velocity (PWV) and blood pressure (BP). GD and these risk factors are all associated with lower levels of vitamin D. We aimed to assess the effect of supplemental vitamin D on PWV and BP in GD. M...

journal_title：Endocrine

authors： Grove-Laugesen D,Malmstroem S,Ebbehoj E,Riis AL,Watt T,Hansen KW,Rejnmark L

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:The aim of this study is to investigate in a population of adolescents living in Regione Campania, undergoing sun exposure at least 9 months per year the prevalence of severe deficiency (<20 ng/ml) or insufficiency (21-29 ng/ml) of 25-Hydroxyvitamin D (25(OH)D) levels and its relationship with individual body w...

journal_title：Endocrine

authors： Colao A,Muscogiuri G,Rubino M,Vuolo L,Pivonello C,Sabatino P,Pizzo M,Campanile G,Fittipaldi R,Lombardi G,Di Somma C

更新日期：2015-06-01 00:00:00

abstract：:Autoimmune thyroid diseases (AITDs) (Hashimoto thyroiditis and Graves' disease) are complex polygenic disorders with multiple genes thought to contribute to the risk of disease. The contribution of these genes differs by different populations. The PTPN22 gene is reported to be associated with multiple autoimmune disea...

journal_title：Endocrine

authors： Alkhateeb A,Marzouka NA,Tashtoush R

更新日期：2013-12-01 00:00:00

abstract：:Taking metformin with a meal has been shown to decrease bioavailability of metformin. We hypothesized that taking metformin 30 min before a meal improves glucose metabolism. As an animal model, 18 Zucker-rats were divided into three groups as follows: no medication (Control), metformin (600 mg/kg) with meal (Met), and...

journal_title：Endocrine

authors： Hashimoto Y,Tanaka M,Okada H,Mistuhashi K,Kimura T,Kitagawa N,Fukuda T,Majima S,Fukuda Y,Tanaka Y,Yamada S,Senmaru T,Hamaguchi M,Asano M,Yamazaki M,Oda Y,Hasegawa G,Nakamura N,Fukui M

更新日期：2016-05-01 00:00:00

abstract：:Thyroid hormones are now recognized to change in different disease states with important consequences on severity and prognosis of disease. However, little is known about thyroid hormones' alterations in acute liver failure (ALF). To study the changes in thyroid hormones and cardiac thyroid receptors during ALF, we su...

journal_title：Endocrine

authors： Kostopanagiotou G,Kalimeris K,Mourouzis I,Kostopanagiotou K,Arkadopoulos N,Panagopoulos D,Papoutsidakis N,Chranioti A,Pafiti A,Spanou D,Smyrniotis V,Pantos C

更新日期：2009-10-01 00:00:00

abstract：:The role of membrane-associated tubulin in TRH receptor-G protein coupling was investigated with the use of compounds that influence tubulin function. TRH-stimulated G protein GTPase activity in GH(3) cell membranes was used to determine receptor-G protein coupling. TRH-stimulated GTPase activity was abolished by G(qα...

journal_title：Endocrine

authors： Ravindra R,Forman LJ,Patel SA

更新日期：1996-02-01 00:00:00

abstract：:Overproduction of proinflammatory factors is associated with obesity and diabetes. Interleukin (IL)-18 as a member of IL-1 cytokine family is increased in obese, in diabetic, and even in polycystic ovary syndrome (PCOS) patients. In the present study we evaluated the association of serum IL-18 levels with insulin resi...

journal_title：Endocrine

authors： Zhang YF,Yang YS,Hong J,Gu WQ,Shen CF,Xu M,Du PF,Li XY,Ning G

更新日期：2006-06-01 00:00:00

abstract：:The A1 adenosine receptor (A1AR) exerts important biological effects in the mammalian biology. To provide insights into the role A1AR action in human physiology, we characterized the pharmacologic properties of the human A1AR, examined somatic sites of A1AR gene expression, and identified the chromosomal location of t...

journal_title：Endocrine

authors： Rivkees SA,Lasbury ME,Stiles GS,Henegariu O,Curtis C,Vance G

更新日期：1995-09-01 00:00:00

abstract：:Follicle-stimulating hormone is synthesized and secreted as a mixture of heterogeneous isoforms that differ from each other in carbohydrate structure, biological potency, and plasma half-life. The relative abundance of the FSH isoforms will depend on the endocrine status of the donor at the time of sample collection. ...

journal_title：Endocrine

authors： Olivares A,Söderlund D,Castro-Fernández C,Zariñán T,Zambrano E,Méndez JP,Ulloa-Aguirre A

更新日期：2004-03-01 00:00:00

abstract：:The treatment of acromegaly is based on surgery, drugs, and radiotherapy as a third-line option. Fractionated stereotactic radiotherapy (FSRT) is a new technique with a need for long-term evaluation. The purpose of the study was to evaluate long-term results of FSRT in acromegaly. Overall, 34 patients [sex ratio 1.12,...

journal_title：Endocrine

authors： Diallo AM,Colin P,Litre CF,Diallo MM,Decoudier B,Bertoin F,Higel B,Patey M,Rousseaux P,Delemer B

更新日期：2015-12-01 00:00:00

abstract：:The possible association between low skeletal muscle mass and cardiovascular disease (CVD) risk factors necessitates estimation of muscle mass even in subjects with normal body mass index (BMI). This study was aimed to investigate optimal cutoffs for skeletal muscle mass reflecting CVD risk factors and to evaluate the...

journal_title：Endocrine

authors： Kim Y,Han BD,Han K,Shin KE,Lee H,Kim TR,Cho KH,Kim DH,Kim YH,Kim H,Nam GE

更新日期：2015-11-01 00:00:00

abstract：:Regulation of energy homeostasis is tightly controlled by the central nervous system (CNS). Several key areas such as the hypothalamus and brainstem receive and integrate signals conveying energy status from the periphery, such as leptin, thyroid hormones, and insulin, ultimately leading to modulation of food intake, ...

journal_title：Endocrine

authors： Seoane-Collazo P,Fernø J,Gonzalez F,Diéguez C,Leis R,Nogueiras R,López M

更新日期：2015-11-01 00:00:00

abstract：:It is well known that TSH plays a major role in the secretion of thyroid hormones, maintenance of thyroid specific gene expression, and gland growth. In this study, we aimed to evaluate association between tests of thyroid functions (fT3, fT4, TSH) and differentiated thyroid carcinoma. 441 patients operated for nodula...

journal_title：Endocrine

authors： Gul K,Ozdemir D,Dirikoc A,Oguz A,Tuzun D,Baser H,Ersoy R,Cakir B

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Wolfram syndrome (WFS) is a rare, monogenic neurodegenerative syndrome characterised by insulin requiring non-autoimmune diabetes mellitus (DM) and optic atrophy which are usually the earliest and commonest manifestations. However, there are other features which are under-recognized, adding to morbidity and ...

journal_title：Endocrine

authors： Das L,Rai A,Mavuduru R,Vaiphei K,Sharma A,Gupta V,Bhadada SK,Lodha S,Panda N,Bhansali A,Singh P,Dutta P

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:In previous studies, associations between breast-milk cortisol levels obtained on one occasion and infant neurodevelopment were demonstrated. However, more recent evidence indicates that breast-milk cortisol and cortisone concentrations follow the diurnal rhythm of maternal hypothalamus-pituitary-adrenal axis, ...

journal_title：Endocrine

authors： Toorop AA,van der Voorn B,Hollanders JJ,Dijkstra LR,Dolman KM,Heijboer AC,Rotteveel J,Honig A,Finken MJJ

更新日期：2020-06-01 00:00:00