当前位置： SCI文献检索 > ENDOCRINE期刊下所有文献 > Inhibition of corticosteroid-binding globulin caused by a severe stressor is apparently mediated by the adrenal but not by glucocorticoid receptors.

Inhibition of corticosteroid-binding globulin caused by a severe stressor is apparently mediated by the adrenal but not by glucocorticoid receptors.

Abstract：

:The effect of stress on serum corticosteroid-binding globulin (CBG) was studied in adult male Sprague-Dawley rats. CBG was measured either by a homologous radioimmunoassay (RIA) or by a binding assay (BA) using 3H-corticosterone. Exposure of adult male rats to a severe stressor such as immobilization (IMO) for 1 h did not alter serum CBG levels, but a significant decrease was found after 6 and especially 24 h IMO. This decrease was not observed after 24 h exposure to a milder treatment such as food and water deprivation. The effect of different periods of exposure to two stressors, IMO or restraint, was also studied. The following results were obtained:serum CBG levels were reduced by IMO, but only by restraint; IMO-induced reduction of CBG levels was always observed 24 h after starting exposure to IMO, independently of the actual period of exposure to the stressor; and IMO-induced inhibition of CBG was proportional to the hours of exposure to the stressor. Although IMO-induced inhibition of CBG was prevented by adrenalectomy, a role for glucocorticoid acting through their classical type II receptors is unclear as far as treatment of rats with the glucocorticoid receptor antagonist RU486 (100 mg/kg) did not prevent the inhibition caused by IMO. The present data clearly indicate that acute exposure to a stressor is able to decrease CBG levels provided that duration of exposure to the stressor and its intensity are high and that the effect is tested at least 6 h after the onset of stress. The effect appears to be mediated by some adrenal factor(s) other than glucocorticoids.

journal_name

Endocrine

journal_title

Endocrine

authors

Martí O,Martín M,Gavaldà A,Giralt M,Hidalgo J,Hsu BR,Kuhn RW,Armario A

doi

10.1007/BF02738959

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

159-64

issue

2

eissn

1355-008X

issn

1559-0100

journal_volume

6

pub_type

杂志文章

相关文献

ENDOCRINE文献大全
  • Nonfunctional adrenal incidentalomas may be related to bisphenol-A.

    abstract：PURPOSE:Bisphenol-A (BPA) is an endocrine-disrupting chemical that may affect the hormones and their receptors. The aim of this study is to determine whether BPA has an effect on the development of nonfunctional adrenal incidentaloma (NFAI). METHODS:Fifty patients who were admitted to endocrinology outpatient clinics ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-020-02502-2

    authors： Eker F,Gungunes A,Durmaz S,Kisa U,Celik ZR

    更新日期：2020-09-23 00:00:00

  • Use of sibutramine and other noradrenergic and serotonergic drugs in the management of obesity.

    abstract：:Drugs that act through noradrenergic and serotonergic mechanisms have historically served as the mainstays of pharmacologic treatments for obesity. This review addresses the following three topics: a brief discussion of older weight loss medications approved for short-term use (benzphetamine, phendimetrazine, diethylp...

    journal_title：Endocrine

    pub_type： 杂志文章,评审

    doi：10.1385/ENDO:13:2:193

    authors： Ryan DH

    更新日期：2000-10-01 00:00:00

  • Investigation of thyroid function and blood pressure in school-aged subjects without overt thyroid disease.

    abstract：:This study was performed to ascertain whether a relationship exists between thyroid function and blood pressure in school-aged Chinese subjects without overt thyroid disease. A cross-sectional survey of 880 subjects (541 females and 339 males) aged 7-18 years in Bengbu, Anhui province was conducted. The investigation,...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-011-9517-7

    authors： Chen H,Xi Q,Zhang H,Song B,Liu X,Mao X,Li J,Shen H,Tang W,Zhang J,Wang Z,Duan Y,Liu C

    更新日期：2012-02-01 00:00:00

  • Loss-of-function of SHARPIN causes an osteopenic phenotype in mice.

    abstract：:SHARPIN is a novel protein thought to interact with SHANK family and is widely expressed in multiple tissues/cells, including osteoblasts and osteoclasts. Loss-of-function of Sharpin develops the chronic proliferative dermatitis mutation (CPDM) in mice as well as a severe inflammation in other organs. The actual funct...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-010-9418-1

    authors： Xia T,Liang Y,Ma J,Li M,Gong M,Yu X

    更新日期：2011-04-01 00:00:00

  • Effect of ethanol on regulation of (Na + K)-adenosine triphosphatase by aldosterone and dexamethasone in cultured renal papillary collecting duct cells.

    abstract：:Chronic ethanol exposure causes alterations in biologic membranes of different cell types. (Na + K) adenosine triphosphatase (ATPase), a membrane-bound enzyme inhibited by the acute presence of ethanol, increases its activity in rat kidney after chronic ethanol consumption. The aim of this investigation was to evaluat...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1385/ENDO:19:3:301

    authors： Rodrigo R,Rivera G,Lucero Y,Larraguibel C

    更新日期：2002-12-01 00:00:00

  • Prolactin and sex steroids levels in congenital lifetime isolated GH deficiency.

    abstract：:Growth hormone (GH) and prolactin share similarities in structure and function. We have previously shown that women with congenital isolated GH deficiency (IGHD) caused by a homozygous mutation in the GHRH receptor gene (GHRHR) (MUT/MUT) have a short reproductive life, with anticipated climacteric. At climacteric, the...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-013-9896-z

    authors： Menezes M,Salvatori R,Melo LD,Rocha ÍE,Oliveira CR,Pereira RM,Souza AH,Valença EH,Melo EV,Campos VC,Costa FO,Aguiar-Oliveira MH

    更新日期：2013-08-01 00:00:00

  • MassARRAY-based simultaneous detection of hotspot somatic mutations and recurrent fusion genes in papillary thyroid carcinoma: the PTC-MA assay.

    abstract：PURPOSE:We exploited the MassARRAY (MA) genotyping platform to develop the "PTC-MA assay", which allows the simultaneous detection of 13 hotspot mutations, in the BRAF, KRAS, NRAS, HRAS, TERT, AKT1, PIK3CA, and EIF1AX genes, and six recurrent genetic rearrangements, involving the RET and TRK genes in papillary thyroid ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-017-1483-2

    authors： Pesenti C,Muzza M,Colombo C,Proverbio MC,Farè C,Ferrero S,Miozzo M,Fugazzola L,Tabano S

    更新日期：2018-07-01 00:00:00

  • Antioxidative mechanisms and plasma growth hormone levels: potential relationship in the aging process.

    abstract：:Factors affecting longevity are complex and poorly understood. We have recently found that Ames dwarf mice (df/df), which are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone, live significantly longer than their normal siblings whereas transgenic mice that overexpress GH exhibit reduced li...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1385/ENDO:11:1:41

    authors： Brown-Borg HM,Bode AM,Bartke A

    更新日期：1999-08-01 00:00:00

  • Increased mortality in patients with adrenal incidentalomas and autonomous cortisol secretion: a 13-year retrospective study from one center.

    abstract：PURPOSE:To compare long-term outcomes in patients with adrenal incidentalomas (AIs) with the response to a 1 mg overnight dexamethasone suppression test (DST). METHODS:Consecutive patients with "non-functional" AIs (n = 365) were examined. Patients with overt hormone excess, adrenocortical cancer and known malignancy ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-017-1400-8

    authors： Patrova J,Kjellman M,Wahrenberg H,Falhammar H

    更新日期：2017-11-01 00:00:00

  • Dopamine D2 receptor stimulation alters G-protein expression in rat pituitary intermediate lobe melanotropes.

    abstract：:Stimulation of dopamine D2 receptors inhibits melanotrope pro-opiomelanocortin (POMC) biosynthesis and alpha-melanocyte-stimulating hormone (MSH) secretion. These effects are mediated by G-protein alpha i- and alpha o-subunits and are reversed by stimulating receptors linked to activation of G alpha s protein. Melanot...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/BF02820510

    authors： Sands SA,Dickerson DS,Morris SJ,Chronwall BM

    更新日期：1997-06-01 00:00:00

  • Thyroid hormones alterations during acute liver failure: possible underlying mechanisms and consequences.

    abstract：:Thyroid hormones are now recognized to change in different disease states with important consequences on severity and prognosis of disease. However, little is known about thyroid hormones' alterations in acute liver failure (ALF). To study the changes in thyroid hormones and cardiac thyroid receptors during ALF, we su...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-009-9210-2

    authors： Kostopanagiotou G,Kalimeris K,Mourouzis I,Kostopanagiotou K,Arkadopoulos N,Panagopoulos D,Papoutsidakis N,Chranioti A,Pafiti A,Spanou D,Smyrniotis V,Pantos C

    更新日期：2009-10-01 00:00:00

  • New HRT options for the treatment of menopausal symptoms and the maintenance of quality of life in postmenopausal women.

    abstract：:Quality of life (QoL) is an important aspect that reflects the way people feel and function. The assessment of QoL quality of life is an essential tool for estimating the efficacy of any therapy in different pathophysiological conditions. In normal, healthy women, the perception of QoL can be significantly modified du...

    journal_title：Endocrine

    pub_type： 杂志文章,评审

    doi：10.1385/ENDO:24:3:231

    authors： Gambacciani M

    更新日期：2004-08-01 00:00:00

  • Psychosocial morbidity in Cushing disease: a study from India.

    abstract：:The main objective of this article is to study the psychosocial profile of patients of Cushing disease (CD) in a developing country setting. Eighteen patients with CD underwent a cross-sectional assessment regarding their socio-demographic and clinical profile, life events, social support, coping, dysfunction, quality...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-009-9182-2

    authors： Mattoo SK,Bhansali AK,Gupta N,Grover S,Malhotra R

    更新日期：2009-06-01 00:00:00

  • Predicting the response to glucocorticoid therapy in thyroid-associated ophthalmopathy: mobilizing structural MRI-based quantitative measurements of orbital tissues.

    abstract：PURPOSE:We aimed to evaluate the performance of structural magnetic resonance imaging (MRI)-based quantitative measurements at extraocular muscle (EOM), orbital fat (OF), and especially lacrimal gland (LG) in predicting response to glucocorticoid (GC) in patients with active and moderate-severe thyroid-associated ophth...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-020-02367-5

    authors： Hu H,Xu XQ,Chen L,Chen W,Wu Q,Chen HH,Zhu H,Shi HB,Wu FY

    更新日期：2020-11-01 00:00:00

  • The role of a new polyclonal competitive thyroglobulin assay in the follow-up of patients with differentiated thyroid cancer with structural disease but low levels of serum thyroglobulin by immunometric and LC-MS/MS methods.

    abstract：PURPOSE:The aims of this study were to assess the role of an in-house competitive thyroglobulin assay (Tg-c) in the follow-up of metastatic differentiated thyroid carcinoma (DTC) patients who presented underestimated Tg measurements by immunometric assays (Tg-IMA) and to compare the results with IMA and LC-MS/MS Tg met...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-020-02526-8

    authors： Guastapaglia L,Kasamatsu TS,Nakabashi CCD,Camacho CP,Maciel RMB,Vieira JGH,Biscolla RPM

    更新日期：2020-11-22 00:00:00

  • Interference at work: a case report of a malfunctioning insulin pump.

    abstract：:Insulin pumps operate almost universally in the work environment. Tubeless insulin pumps are a relatively recent development for management of insulin-dependent diabetes. This is the first report of location-dependent failure of insulin pump function, possibly due to external interference, occurring only in the settin...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-008-9122-6

    authors： Reiher AE,Gallagher TA,Emanuele MA

    更新日期：2009-02-01 00:00:00

  • Treatment of multiresistant prolactinomas with a combination of cabergoline and octreotide LAR.

    abstract：BACKGROUND AND OBJECTIVES:Dopamine agonist (DA)-resistant prolactinomas are rare but they constitute a real challenge, since there are few therapeutic alternatives left for these patients. DESIGN AND SETTING:Proof-of-concept study at a tertiary care, referral center. PATIENTS AND METHODS:The studied population consis...

    journal_title：Endocrine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s12020-018-1638-9

    authors： Sosa-Eroza E,Espinosa E,Ramírez-Rentería C,Mendoza V,Arreola R,Mercado M

    更新日期：2018-08-01 00:00:00

  • Decreased blood activity of glucose-6-phosphate dehydrogenase associates with increased risk for diabetes mellitus.

    abstract：:Glucose-6-phosphate dehydrogenase (G6PD) deficiency predisposes affected individuals highly susceptible to oxidative stress, which is one of the risk factors for diabetes. To evaluate the relationship between blood level of G6PD activity and diabetes in Taiwan, blood G6PD activity was analyzed among 237 patients with ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1385/ENDO:19:2:191

    authors： Wan GH,Tsai SC,Chiu DT

    更新日期：2002-11-01 00:00:00

  • Reference values for handgrip strength in young people of both sexes.

    abstract：:The handgrip strength is considered an excellent predictor of morbidity and mortality for acute and long term outcomes. In fact, several studies showed that the reduced handgrip strength is correlated to all-cause mortality in both middle aged and elderly subjects. Nevertheless, defined reference values of handgrip st...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-012-9733-9

    authors： Montalcini T,Migliaccio V,Yvelise F,Rotundo S,Mazza E,Liberato A,Pujia A

    更新日期：2013-04-01 00:00:00

  • Ovarian transcriptomes as a tool for a global approach of genes modulated by gonadotropic hormones in human ovarian granulosa cells.

    abstract：:Follicle-stimulating hormone (FSH) is a key stimulant for the development of the ovarian follicle, while luteinizing hormone (LH) plays a major role in triggering ovulation and luteinization. Both FSH and LH are glycoprotein hormones that share the same alpha subunit but bind to specific seven transmembrane-domain G c...

    journal_title：Endocrine

    pub_type： 杂志文章,评审

    doi：10.1385/endo:26:3:259

    authors： Friedmann S,Dantes A,Amsterdam A

    更新日期：2005-04-01 00:00:00

  • Serum anti-mullerian hormone and all-cause mortality in men.

    abstract：:Several studies have examined an association of anti-mullerian hormone to various risk factors for mortality, however, to the best of our knowledge, no study has reported a direct relationship between anti-mullerian hormone and all-cause mortality. Therefore, we examined the relationship between baseline anti-mulleria...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-016-1071-x

    authors： Qayyum R,Akbar S

    更新日期：2016-10-01 00:00:00

  • Vasopressin, oxytocin, corticotrophin-releasing factor, and sodium responses during fluoxetine administration in the rat.

    abstract：:Hyponatremia has been observed in elderly patients treated with the selective serotonin reuptake inhibitor (SSRI) fluoxetine. The pathogenesis of this effect is not known, but enhanced release of vasopressin (VP) and its renal actions may be a possible mechanism. Excess secretion of VP in combination with large fluid ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1385/ENDO:8:1:13

    authors： Marar IE,Amico JA

    更新日期：1998-02-01 00:00:00

  • Interleukin-18 enhances glucose uptake in 3T3-L1 adipocytes.

    abstract：:In order to characterize the potential causative effects of interleukin-18 (IL-18) on insulin resistance, we measured glucose uptake in 3T3-L1 adipocytes treated with mouse recombinant IL-18. IL-18 surprisingly enhanced, rather than reduced insulin-mediated glucose uptake in adipocytes. Moreover IL-18 could counteract...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-008-9048-z

    authors： Yang YS,Li XY,Hong J,Gu WQ,Zhang YF,Yang J,Song HD,Chen JL,Ning G

    更新日期：2007-12-01 00:00:00

  • Gonadotropin-releasing hormone receptor gene expression in rat anterior pituitary.

    abstract：:Gonadotropin-releasing hormone (GnRH) effects on the lactotroph function have been widely studied, but they probably result from paracrine interactions. No visual data about GnRH receptor in the pituitary are available. In order to identify the GnRH target cells in the pituitary of adult rats, the cellular distributio...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/BF02782760

    authors： Mertani HC,Testart C,Ouhtit A,Brisson C,Morel G

    更新日期：1996-04-01 00:00:00

  • Insulin like growth factor-1 (IGF-1) decreases ischemia-reperfusion induced apoptosis and necrosis in diabetic rats.

    abstract：:Previous evidence supports the view that insulin, as well as insulin like growth factor-1 (IGF-1) provides neurotropic support for neurons in the central nervous system (CNS) and peripheral nervous system (PNS). In the present study we evaluated the effects of the intravenous infusion of IGF-1 on both necrosis and apo...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-007-0012-0

    authors： Rizk NN,Myatt-Jones J,Rafols J,Dunbar JC

    更新日期：2007-02-01 00:00:00

  • Surgical biopsies in patients with central diabetes insipidus and thickened pituitary stalks.

    abstract：:Thickened pituitary stalks (TPSs) on magnetic resonance imaging (MRI) result from diverse pathologies; therefore, it is essential to make specific diagnoses for clinical decision-making. The diagnoses and indications for surgical biopsies in patients with central diabetes insipidus (CDI) and TPSs are thoroughly discus...

    journal_title：Endocrine

    pub_type： 信件

    doi：10.1007/s12020-014-0184-3

    authors： Jian F,Bian L,Sun S,Yang J,Chen X,Chen Y,Ma Q,Miao F,Wang W,Ning G,Sun Q

    更新日期：2014-09-01 00:00:00

  • Diurnal rhythmicity in breast-milk glucocorticoids, and infant behavior and sleep at age 3 months.

    abstract：PURPOSE:In previous studies, associations between breast-milk cortisol levels obtained on one occasion and infant neurodevelopment were demonstrated. However, more recent evidence indicates that breast-milk cortisol and cortisone concentrations follow the diurnal rhythm of maternal hypothalamus-pituitary-adrenal axis, ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-020-02273-w

    authors： Toorop AA,van der Voorn B,Hollanders JJ,Dijkstra LR,Dolman KM,Heijboer AC,Rotteveel J,Honig A,Finken MJJ

    更新日期：2020-06-01 00:00:00

  • Effects of one year simvastatin and atorvastatin treatments on acute phase reactants in uncontrolled type 2 diabetic patients.

    abstract：:Type 2 diabetes mellitus is the leading cause of macrovascular diseases and related death. Additionally, diabetes mellitus is frequently complicated by other cardiovascular risk factors, such as hypercholesterolemia, hypertension, obesity, hypercoagulability, and inflammation. We wanted to evaluate and compare the eff...

    journal_title：Endocrine

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s12020-009-9157-3

    authors： Ukinc K,Ersoz HO,Erem C,Hacihasanoglu AB,Karti SS

    更新日期：2009-06-01 00:00:00

  • Sex-related differences in self-care behaviors of adults with type 2 diabetes mellitus.

    abstract：PURPOSE:To describe sex-related differences in self-care; to identify determinants of self-care according to sex, and to investigate how sex interacts with the effect of clinical and socio-demographic variables on self-care in adults with Type 2 Diabetes Mellitus (T2DM). METHODS:Cross-sectional multicentre study with ...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-020-02189-5

    authors： Caruso R,Rebora P,Luciani M,Di Mauro S,Ausili D

    更新日期：2020-02-01 00:00:00

  • Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population.

    abstract：:Autoimmune thyroid diseases (AITDs) (Hashimoto thyroiditis and Graves' disease) are complex polygenic disorders with multiple genes thought to contribute to the risk of disease. The contribution of these genes differs by different populations. The PTPN22 gene is reported to be associated with multiple autoimmune disea...

    journal_title：Endocrine

    pub_type： 杂志文章

    doi：10.1007/s12020-013-9908-z

    authors： Alkhateeb A,Marzouka NA,Tashtoush R

    更新日期：2013-12-01 00:00:00