Abstract:
:Drugs that act through noradrenergic and serotonergic mechanisms have historically served as the mainstays of pharmacologic treatments for obesity. This review addresses the following three topics: a brief discussion of older weight loss medications approved for short-term use (benzphetamine, phendimetrazine, diethylpropion, mazindol, and phentermine), as well as over-the-counter adrenergic drugs (phenylpropanolamine and ephedrine); recent clinical studies documenting the safety and efficacy of a new medication for obesity treatment, sibutramine, recently approved by the Food and Drug Administration for long-term use; and recent studies characterizing the valvulopathy associated with fenfluramine and dexfenfluramine, serotonergic medications for obesity which have been removed from the markets.
journal_name
Endocrinejournal_title
Endocrineauthors
Ryan DHdoi
10.1385/ENDO:13:2:193subject
Has Abstractpub_date
2000-10-01 00:00:00pages
193-9issue
2eissn
1355-008Xissn
1559-0100pii
ENDO:13:2:193journal_volume
13pub_type
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