Anti-Saccaromyces Cerevisiae antibodies (ASCA) are elevated in autoimmune thyroid disease ASCA in autoimmune thyroid disease.

abstract：UNLABELLED:Gallium-68 somatostatin receptor (SMSR) positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) are valuable diagnostic tools for patients with neuroendocrine tumours (NETs). To date, a meta-analysis about the diagnostic accuracy of these imaging methods is lacking. A...

journal_title：Endocrine

authors： Treglia G,Castaldi P,Rindi G,Giordano A,Rufini V

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:The aims of this study were to assess the role of an in-house competitive thyroglobulin assay (Tg-c) in the follow-up of metastatic differentiated thyroid carcinoma (DTC) patients who presented underestimated Tg measurements by immunometric assays (Tg-IMA) and to compare the results with IMA and LC-MS/MS Tg met...

journal_title：Endocrine

authors： Guastapaglia L,Kasamatsu TS,Nakabashi CCD,Camacho CP,Maciel RMB,Vieira JGH,Biscolla RPM

更新日期：2020-11-22 00:00:00

abstract：PURPOSE:The distinction between congenital hypogonadotropic hypogonadism (CHH) and constitutional delay of growth and puberty (CDGP) in patients with delayed puberty is difficult to distinguish, but important for timely treatment. The aim of this study is to perform a systematic review and meta-analysis to determine th...

journal_title：Endocrine

authors： Gao Y,Du Q,Liu L,Liao Z

更新日期：2021-01-19 00:00:00

abstract：:The present study was designed to determine whether an association exists between HPA activity and cytokine production in major depression (MD). In 9 patients with MD and 11 control subjects of both sexes, all drug-free, activity of the HPA axis was evaluated by circadian rhythm of plasma cortisol, 24-h free urinary c...

journal_title：Endocrine

authors： Humphreys D,Schlesinger L,Lopez M,Araya AV

更新日期：2006-12-01 00:00:00

abstract：:Diabetes with hypertension is characterized by increased cerebrovascular pathology and poorer outcomes following stroke. In this study we evaluated the effect of global brain ischemia on brain metabolic parameters in normal and diabetic rats treated with a dihydropyridine calcium antagonist, felodipine. Normal and dia...

journal_title：Endocrine

authors： Levy J,Zhu Z,Dunbar JC

更新日期：2004-11-01 00:00:00

abstract：:Leptin shows pleiotropic effects in organisms including an important role in the regulation of glucose homeostasis. Elevated serum leptin, particularly in obese individuals, is a warning sign of energy imbalance, hyperinsulinemia, insulin resistance and other metabolic risk factors that are strongly associated with ty...

journal_title：Endocrine

authors： Pliszka M,Oleszczak B,Szablewski L

更新日期：2015-05-01 00:00:00

abstract：:Silent information regulator T1 (SIRT1) plays several key roles in the regulation of lipid and glucose homoeostasis. In this study, we investigated the potential role of SIRT1 in hyperuricemia and explored possible mechanisms. Significant hyperuricemia was detected in C57BL/6 mice treated with oxonate and yeast polysa...

journal_title：Endocrine

authors： Wang J,Zhu XX,Liu L,Xue Y,Yang X,Zou HJ

更新日期：2016-08-01 00:00:00

abstract：:To investigate a possible neurotropic role for thyrotropin-releasing hormone (TRH) in the central nervous system, we used recombinant antisense TRH adenovirus (TRHav) to "knock out" TRH in cultured 17-d fetal rat diencephalon. The morphology along with beta-galactosidase (beta-gal) enzyme histochemistry (X-gal stainin...

journal_title：Endocrine

authors： Luo LG,Lee SL,Lechan RM,Jackson IM

更新日期：2001-06-01 00:00:00

abstract：PURPOSE:To describe sex-related differences in self-care; to identify determinants of self-care according to sex, and to investigate how sex interacts with the effect of clinical and socio-demographic variables on self-care in adults with Type 2 Diabetes Mellitus (T2DM). METHODS:Cross-sectional multicentre study with ...

journal_title：Endocrine

authors： Caruso R,Rebora P,Luciani M,Di Mauro S,Ausili D

更新日期：2020-02-01 00:00:00

abstract：:The prevalence of adrenal incidentaloma has increased with the increasing use of imaging techniques. While majority are benign adenoma, a small but significant minority may be primary adrenal carcinoma or have endocrine hyper secretion. Existing guidance suggests that excess catecholamine and cortisol secretion should...

journal_title：Endocrine

authors： Bujawansa S,Bowen-Jones D

更新日期：2011-08-01 00:00:00

abstract：:Fibroadenomas are the most common benign breast tumors, occurring mainly in young women. Their responses to the hormonal environment are similar to those of normal breast tissue, which suggests that steroid receptors may play a role in tumor development. We evaluated the gene and protein expression of progesterone rec...

journal_title：Endocrine

authors： Branchini G,Schneider L,Cericatto R,Capp E,Brum IS

更新日期：2009-06-01 00:00:00

abstract：:The androgen receptor (AR) plays a critical role in sexual differentiation and in the virilization of the male reproductive system. A clear understanding of AR expression at the early stages of sexual development will help elucidate the sensitivity of perinatal animals to endocrine modulation by external agents, such ...

journal_title：Endocrine

authors： You L,Sar M

更新日期：1998-12-01 00:00:00

abstract：:Follicle-stimulating hormone (FSH) is a key stimulant for the development of the ovarian follicle, while luteinizing hormone (LH) plays a major role in triggering ovulation and luteinization. Both FSH and LH are glycoprotein hormones that share the same alpha subunit but bind to specific seven transmembrane-domain G c...

journal_title：Endocrine

authors： Friedmann S,Dantes A,Amsterdam A

更新日期：2005-04-01 00:00:00

abstract：:Glucocorticoid hormones potentiate the toxic effects of neuronal stressors. Alteration of gene expression by glucocorticoids could contribute to neuronal susceptibility by downregulating the synthesis of proteins necessary to adapt to challenge. Using heat shock of hippocampal slices as a model for cellular insult, pr...

journal_title：Endocrine

authors： Barr CS,Dokas LA

更新日期：1998-04-01 00:00:00

abstract：:Studies designed to evaluate the short-term effects of incretin-related drugs in subjects with cardiac disease are still preliminary. In patients with heart failure, two of five studies showed that glucagon-like peptide-1 (GLP-1) infusion was associated with an absolute increase in left ventricular ejection fraction (...

journal_title：Endocrine

authors： Mikhail N

更新日期：2014-09-01 00:00:00

abstract：:The process of homo- and/or heterodimerization of G-protein coupled receptors (GPCRs) and receptor tyrosine kinase (RTK) families are crucial for implicating the fundamental properties of receptor proteins including receptor expression, trafficking, and desensitization as well as signal transduction. The members of GP...

journal_title：Endocrine

authors： Kumar U

更新日期：2011-10-01 00:00:00

abstract：:An elevation in hearing thresholds and decrease in hearing sensitivity in adults, particularly due to aging, are quite common. Recent studies have shown that, apart from aging, various other factors also play a role in auditory changes. Studies on the association of hearing loss (HL) with obesity are limited in advanc...

journal_title：Endocrine

authors： Üçler R,Turan M,Garça F,Acar İ,Atmaca M,Çankaya H

更新日期：2016-04-01 00:00:00

abstract：:Strict glucose control is a well-proven therapeutic approach for peripheral neuropathies in patients with diabetes. Alpha lipoic acid (ALA) has also been accepted as a therapeutic agent for diabetic peripheral neuropathy (DPN) in the respect of pathogenesis. However, the potential of ALA as a treatment for DPN in comp...

journal_title：Endocrine

authors： Lee KA,Lee NY,Park TS,Jin HY

更新日期：2018-07-01 00:00:00

abstract：:Hypoxia is well known to decrease appetite and weight gain in growing rats, and to induce weight loss in humans. It has been hypothesized that this is mediated by a change in ghrelin, an orexigenic peptide synthesized and released primarily from the stomach. Rats were exposed to hypoxia for 7 d as neonates (birth-7 d ...

journal_title：Endocrine

authors： Raff H

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:Multiple endocrine neoplasia type 1 is a rare tumor syndrome caused by germline mutations of MEN1 gene. Phenotype varies widely, and no definitive correlation with the genotype has been observed. Mutation-negative patients with MEN1-associated tumors represent phenocopies. By comparing mutation-positive and mut...

journal_title：Endocrine

authors： Kövesdi A,Tóth M,Butz H,Szücs N,Sármán B,Pusztai P,Tőke J,Reismann P,Fáklya M,Tóth G,Somogyi A,Borka K,Erdei A,Nagy EV,Deák V,Valkusz Z,Igaz P,Patócs A,Grolmusz VK

更新日期：2019-08-01 00:00:00

abstract：:The prevalence of obesity and type 2 diabetes mellitus epidemics presents a great health problem worldwide. Beside the changes in diet and decreased physical activity, there is growing interest in endocrine disrupting chemicals that may have effects on these conditions. Among them, the role of certain phthalates and b...

journal_title：Endocrine

authors： Stojanoska MM,Milosevic N,Milic N,Abenavoli L

更新日期：2017-03-01 00:00:00

abstract：:In order to identify GH target cells in human tissues, we investigated the celiuiar distribution of human GH receptor (GHR) messenger RNA. This was performed byin situ hybridization and Northern blot hybridization using complementary radioactive DNA probe encoding part of the extracellular domain of the GHR. Several t...

journal_title：Endocrine

authors： Mertani HC,Delehaye-Zervas MC,Martini JF,Postel-Vinay MC,Morel G

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND AND AIM:A close relationship between adiposity and increased cortisol levels is well established in patients with endogenous hypercortisolism. Nevertheless, hypothalamic-pituitary-adrenal (HPA) axis regulation in overweight subjects is still a matter of concern. We studied free cortisol (urinary free cortiso...

journal_title：Endocrine

authors： Ceccato F,Lizzul L,Barbot M,Scaroni C

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:This study aimed to analyze the clinical and genetic characteristics of Chinese children with congenital hyperinsulinemia (CHI) that is spontaneously relieved. METHODS:The patient group comprised 200 children with CHI that were treated at the Beijing Children's Hospital from January 2006 to December 2018. Th...

journal_title：Endocrine

authors： Xu ZD,Hui PP,Zhang W,Zeng Q,Zhang L,Liu M,Yan J,Wu YJ,Sang YM

更新日期：2021-01-27 00:00:00

abstract：:The aim of this study is to investigate the correlation between serum microRNA-217 and the severity of diabetic kidney disease determined by albuminuria. Four hundred ninety five type 2 diabetes patients were divided into three groups: normoalbuminuric group, microalbuminuric group, and macroalbuminuric group. Serum m...

journal_title：Endocrine

authors： Shao Y,Ren H,Lv C,Ma X,Wu C,Wang Q

更新日期：2017-01-01 00:00:00

abstract：:Polymorphisms of the NR3C1 (glucocorticoid receptor) gene have been reported to be associated with altered glucocorticoids sensitivity and changes in body composition and metabolic parameters. This study explored the relationship between single nucleotide polymorphisms (SNPs) of the NR3C1 gene and metabolic syndrome (...

journal_title：Endocrine

authors： Yan YX,Dong J,Zhang J,Liu F,Wang W,Zhang L,He Y

更新日期：2014-12-01 00:00:00

abstract：:The therapeutic activity of 131I administered to patients with Graves' disease can be calculated by means of Marinelli's formula. The thyroidal iodine uptake (131IUmax) needed for the calculation is usually determined with the use of 131I. The purpose of the paper was to estimate 131IUmax on the basis of technetium up...

journal_title：Endocrine

authors： Szumowski P,Mojsak M,Abdelrazek S,Sykała M,Amelian-Fiłonowicz A,Jurgilewicz D,Myśliwiec J

更新日期：2016-12-01 00:00:00

abstract：:Progesterone (P(4)) and estradiol (E(2)) regulate many cell functions through their interaction with specific intracellular receptors, which require the participation of coactivators such as SRC-1 and SRC-3 for enhancing their transcriptional activity. Coactivator expression is altered in many cancers and in some of t...

journal_title：Endocrine

authors： Hernández-Hernández OT,Rodríguez-Dorantes M,González-Arenas A,Camacho-Arroyo I

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:In order to study the association of G241R polymorphism of ICAM-1 gene with an earlier onset of Graves' disease (GD) and the susceptibility of K469E polymorphism to Graves' ophthalmopathy (GO) in Chinese population. STUDY DESIGN:A case-control and replication study was performed in 212 GD patients and 204 he...

journal_title：Endocrine

authors： Wang S,Sun H,Chen HY,Zhao ZF,Yang Y,Zhao YJ,Cui B,Ning G

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To compare long-term outcomes in patients with adrenal incidentalomas (AIs) with the response to a 1 mg overnight dexamethasone suppression test (DST). METHODS:Consecutive patients with "non-functional" AIs (n = 365) were examined. Patients with overt hormone excess, adrenocortical cancer and known malignancy ...

journal_title：Endocrine

authors： Patrova J,Kjellman M,Wahrenberg H,Falhammar H

更新日期：2017-11-01 00:00:00