Suppression by exendin(9-39)amide of glucagon-like peptide-1 insulinotropic action in rats infused with dimethyl ester of succinic acid.

abstract：:The A1 adenosine receptor (A1AR) exerts important biological effects in the mammalian biology. To provide insights into the role A1AR action in human physiology, we characterized the pharmacologic properties of the human A1AR, examined somatic sites of A1AR gene expression, and identified the chromosomal location of t...

journal_title：Endocrine

authors： Rivkees SA,Lasbury ME,Stiles GS,Henegariu O,Curtis C,Vance G

更新日期：1995-09-01 00:00:00

abstract：:Fifty children ages 4-10 yr with type 1 diabetes mellitus volunteered to participate in a study to evaluate and compare a new needle-free device developed for growth hormone delivery. Children answered descriptive questions related to nervousness and worry, hurt or pain, redness or bleeding, and stinging and wetness. ...

journal_title：Endocrine

authors： Silverstein JH,Murray FT,Malasanos T,Myers S,Johnson SB,Frye K,Grossman M

更新日期：2001-06-01 00:00:00

abstract：:Aberrant accumulation of β-catenin plays an important role in a variety of human neoplasms. This can be caused by stabilizing mutation of β-catenin (CTNNB1, exon 3) or by mutation or deregulated expression of other components of the WNT/β-catenin signaling pathway. Accumulation of non-phosphorylated active β-catenin h...

journal_title：Endocrine

authors： Starker LF,Fonseca AL,Akerström G,Björklund P,Westin G,Carling T

更新日期：2012-12-01 00:00:00

abstract：:The prevalence of germ line mutations within the RET-protooncogene and the tumor suppressor genes SDHB, SDHD, and VHL in pheochromocytomas (PC) varies in recent studies from 12 to 24%, if one look at them collectively. DNA was extracted from frozen tumor tissue as well as from blood leukocytes of 36 PC (26 sporadic/10...

journal_title：Endocrine

authors： Waldmann J,Langer P,Habbe N,Fendrich V,Ramaswamy A,Rothmund M,Bartsch DK,Slater EP

更新日期：2009-06-01 00:00:00

abstract：:There have been few reports on the development of metabolic disorders, especially when they are considered as a cluster. The purpose of this study was to describe risk profiles for metabolic syndrome (MetS) in elderly dwellers in Beijing, and to find their transition patterns over time. Data were derived from Beijing ...

journal_title：Endocrine

authors： Tao LX,Wang W,Zhu HP,Huo D,Zhou T,Pan L,Gao Q,Luo YX,Wu LJ,Li X,Tang Z,Guo XH

更新日期：2014-09-01 00:00:00

abstract：:Several studies have examined an association of anti-mullerian hormone to various risk factors for mortality, however, to the best of our knowledge, no study has reported a direct relationship between anti-mullerian hormone and all-cause mortality. Therefore, we examined the relationship between baseline anti-mulleria...

journal_title：Endocrine

authors： Qayyum R,Akbar S

更新日期：2016-10-01 00:00:00

abstract：:Taking metformin with a meal has been shown to decrease bioavailability of metformin. We hypothesized that taking metformin 30 min before a meal improves glucose metabolism. As an animal model, 18 Zucker-rats were divided into three groups as follows: no medication (Control), metformin (600 mg/kg) with meal (Met), and...

journal_title：Endocrine

authors： Hashimoto Y,Tanaka M,Okada H,Mistuhashi K,Kimura T,Kitagawa N,Fukuda T,Majima S,Fukuda Y,Tanaka Y,Yamada S,Senmaru T,Hamaguchi M,Asano M,Yamazaki M,Oda Y,Hasegawa G,Nakamura N,Fukui M

更新日期：2016-05-01 00:00:00

abstract：:The adipocyte-derived catabolic protein leptin alters cell-mediated immunity and cytokine crosstalk. This may provide new insights into the altered immune response, seen in obese individuals. Therefore, we determined the tissue distribution of immune cells in diet-induced obese (dio) and normal weight F344 rats challe...

journal_title：Endocrine

authors： Behrendt P,Buchenauer T,Horn R,Brabant G,Jacobs R,Bode F,Stephan M,Nave H

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:Publications suggesting that thyroid nodule might be associated with insulin resistance and metabolic syndrome are quite interesting. There is a need for studies assessing the relationship between nodule presence and cardiovascular risk in individuals with non-functioning nodular goiter. The purpose of the p...

journal_title：Endocrine

authors： Aydoğan Y,Altay M,Ünsal O,Kaplanoğlu V,Çağır Y,Yıldız C,Beyan E,Ramadan SU

更新日期：2018-11-01 00:00:00

abstract：:Adult-onset growth-hormone (GH) deficiency (GHD) is a rare disorder, which most commonly results from pituitary or peripituitary tumors and their treatment, and is characterized by alterations in body composition, carbohydrate and lipid metabolism, bone mineral density, cardiovascular risk profile and quality of life,...

journal_title：Endocrine

authors： Ramos-Leví AM,Marazuela M

更新日期：2018-05-01 00:00:00

abstract：:Protocols for induction of hyperthyroidism in mice are highly variable and mostly involve short-term thyroid hormone (TH) treatment. In addition, little is known about a possible influence of sex on experimental TH manipulation. Here we analyzed the efficacy of intraperitoneal vs. oral levothyroxine (T4) administratio...

journal_title：Endocrine

authors： Engels K,Rakov H,Zwanziger D,Hönes GS,Rehders M,Brix K,Köhrle J,Möller LC,Führer D

更新日期：2016-10-01 00:00:00

abstract：:Fibroadenomas are the most common benign breast tumors, occurring mainly in young women. Their responses to the hormonal environment are similar to those of normal breast tissue, which suggests that steroid receptors may play a role in tumor development. We evaluated the gene and protein expression of progesterone rec...

journal_title：Endocrine

authors： Branchini G,Schneider L,Cericatto R,Capp E,Brum IS

更新日期：2009-06-01 00:00:00

abstract：:The best repletion and maintenance dosing regimens with cholecalciferol in vitamin D-deficient HIV-1 patients remain unknown. Protease inhibitors (PIs) have been shown to inhibit vitamin D 1α- and 25α-hydroxylation in hepatocyte and monocyte cultures. We therefore evaluated the effect of a single high dose of cholecal...

journal_title：Endocrine

authors： Pepe J,Mezzaroma I,Fantauzzi A,Falciano M,Salotti A,Di Traglia M,Diacinti D,Biondi P,Cipriani C,Cilli M,Minisola S

更新日期：2016-07-01 00:00:00

abstract：:Aging could be due to the accumulation of oxidative damage. On the other hand, growth hormone (GH) and estrogen deficiency induce deleterious effects on different tissues, and hormonal replacement could counteract these effects. We have investigated whether GH and estrogen administration modify some parameters related...

journal_title：Endocrine

authors： Castillo C,Salazar V,Ariznavarreta C,Vara E,Tresguerres JA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Surgical procedures are associated with activation of the hypothalamic-pituitary-adrenal axis (HPA). Studies examining HPA dynamics peri-operatively are limited and the modulating influence of peri-operatively administered glucocorticoids on that is not well established. This investigation examined alteratio...

journal_title：Endocrine

authors： El-Sibai K,Rajpal A,Al-Aridi R,Selman WR,Arafah BM

更新日期：2017-10-01 00:00:00

abstract：:Graves' disease (GD) and Hashimoto's thyroiditis (HT) are both common autoimmune diseases of the thyroid gland (AITD). The IL-4 is involved in both humoral and cellular immunity. The aim of this study was to test whether the IL-4 gene could be used as a genetic marker to predict the development of AITD amongst the Chi...

journal_title：Endocrine

authors： Chen RH,Chang CT,Wang TY,Chen CC,Tsai CH,Tsai FJ

更新日期：2007-10-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a rare disease in which the most common endocrine manifestation is diabetes insipidus (DI). Data on anterior pituitary function in patients with LCH are limited. Thus, the present study investigated anterior pituitary function in LCH patients with DI via the evaluation of clinica...

journal_title：Endocrine

authors： Kurtulmus N,Mert M,Tanakol R,Yarman S

更新日期：2015-04-01 00:00:00

abstract：:To investigate the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey. Seventy-six patients with CPHD were included in this study. Based on clinical, hormonal, and neuro-radiological data, relevant transcription factor genes were evaluated...

journal_title：Endocrine

authors： Baş F,Uyguner ZO,Darendeliler F,Aycan Z,Çetinkaya E,Berberoğlu M,Şiklar Z,Öcal G,Darcan Ş,Gökşen D,Topaloğlu AK,Yüksel B,Özbek MN,Ercan O,Evliyaoğlu O,Çetinkaya S,Şen Y,Atabek E,Toksoy G,Aydin BK,Bundak R

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Thyroid hormone (TH) metabolism can have prognostic significance in brain tumors. We studied the association of common variations in three deiodinase gene single-nucleotide polymorphisms (SNPs) with circulating TH concentrations and prognosis of brain tumor patients. METHODS:Patients admitted for glioma and...

journal_title：Endocrine

authors： Bunevicius A,Laws ER,Saudargiene A,Tamasauskas A,Iervasi G,Deltuva V,Smith TR,Bunevicius R

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Optimal vitamin D status promotes skeletal health and is recommended with specific treatment in individuals at high risk for fragility fractures. A growing body of literature has provided indirect and some direct evidence for possible extraskeletal vitamin D-related effects. PURPOSE AND METHODS:Members of...

journal_title：Endocrine

authors： Cianferotti L,Bertoldo F,Bischoff-Ferrari HA,Bruyere O,Cooper C,Cutolo M,Kanis JA,Kaufman JM,Reginster JY,Rizzoli R,Brandi ML

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:The study aimed to disclose mortality pattern and quantitatively evaluate risks for cause-specific mortality among thyroid cancer survivors. METHODS:We included 173,710 patients from the Surveillance, Epidemiology, and End Results (SEER) database with thyroid cancer diagnosed between 1975 and 2015. Standardize...

journal_title：Endocrine

authors： Du B,Wang F,Wu L,Wang Z,Zhang D,Huang Z,Gao L,Li Y,Liang C,Li P,Yao R

更新日期：2020-08-08 00:00:00

abstract：:Increasing evidence suggests that inflammatory response may be a critical component of different brain pathologies. However, the role played by this reaction is not fully understood. The present findings suggest that neuroinflammtory mediators such as cytokines may be involved in a number of key steps in the pathologi...

journal_title：Endocrine

authors： Członkowska A,Ciesielska A,Gromadzka G,Kurkowska-Jastrzebska I

更新日期：2006-04-01 00:00:00

abstract：:Adrenocorticotropin-secreting pituitary tumor represents about 10 % of pituitary adenomas and at the time of diagnosis most of them are microadenomas. Transsphenoidal surgery is the first-line treatment of Cushing's disease and accurate localization of the tumor within the gland is essential for selectively removing t...

journal_title：Endocrine

authors： Vitale G,Tortora F,Baldelli R,Cocchiara F,Paragliola RM,Sbardella E,Simeoli C,Caranci F,Pivonello R,Colao A,A.B.C. Group.

更新日期：2017-03-01 00:00:00

abstract：:The present study in female rats determined the effects of experimental hyperthyroidsm on hemorheological parameters and fibrinogen concentration. To induce experimental hyperthyroidism L-thyroxine (0.4 mg/100 g fodder) was added to the fodder of the experimental group rats for 20 d. After experimental duration, T3, T...

journal_title：Endocrine

authors： Ozdemir S,Yücel R,Dariyerli N,Toplan S,Akyolcu MC,Yigit G,Hatemi H

更新日期：2006-10-01 00:00:00

abstract：:Thioredoxin-interacting protein (TXNIP) is a known important regulatory protein of islet β-cell biology and function, but the detailed mechanism is not clear. Autophagy plays a pivotal role in maintaining cellular homoeostasis. This study aimed to elucidate the influence of TXNIP on the autophagy of β-cell. In this st...

journal_title：Endocrine

authors： Deng W,Li Y,Ren Z,He Q,Jia Y,Liu Y,Zhang W,Gan X,Liu D

更新日期：2020-12-01 00:00:00

abstract：:It is well established that hypothalamic dopamine (DA) is the major physiologic regulator of prolactin (PRL) secretion, exerting a tonic inhibition throughout most of the estrous cycle. A dramatic drop in the amount of DA perfusing the anterior pituitary occurs in the afternoon of proestrus and is critical for the pro...

journal_title：Endocrine

authors： Gregerson KA

更新日期：2003-02-01 00:00:00

abstract：:Pituitary tumors are highly vascular neoplasms, which suggest an important role of angiogenesis in pituitary tumor growth. We used the human pituitary cell line (HP75) to examine the effects of the growth factors TGFbeta1, bFGF, and EGF on cell growth, and on the regulation of the pro-angiogenic growth factor VEGF-A a...

journal_title：Endocrine

authors： Horiguchi H,Jin L,Ruebel KH,Scheithauer BW,Lloyd RV

更新日期：2004-07-01 00:00:00

abstract：:Persistent organic pollutants (POPs) are endocrine-disrupting chemicals associated with metabolic syndrome and type 2 diabetes. In humans, little is known about their potential role on obesity. Adiponectin augments the effects of insulin on glucose homeostasis. The expression of adiponectin is reduced in obesity, insu...

journal_title：Endocrine

authors： Lim JE,Jee SH

更新日期：2015-02-01 00:00:00

abstract：:RF amide peptide family with distinctive terminal -Arg-Phe-NH(2) signature is evolutionarily conserved from invertebrates to mammals. These neuropeptides have been shown to affect diverse functions in invertebrates and vertebrates including influencing pituitary hormone secretion. More recently, two members of this fa...

journal_title：Endocrine

authors： Qaiser F,Wahab F,Wiqar MA,Hashim R,Leprince J,Vaudry H,Tena-Sempere M,Shahab M

更新日期：2012-12-01 00:00:00

abstract：:Oxytocin (OT) and arginine-vasopressin (AVP) are two major neurohypophysary nonapeptides that have impor-tant roles during pregnancy and labor. Using the expiant model at term, we have examined the effect of physiologic concentrations of both nonapeptides on placental hormone secretion. We found that OT had a dose-dep...

journal_title：Endocrine

authors： Barnea ER,Maruo T,Schurtz-Swirsky R

更新日期：1995-04-01 00:00:00