The effects of experimental hyperthyroidism on hemorheology and plasma fibrinogen concentration.

abstract：:The effect of stress on serum corticosteroid-binding globulin (CBG) was studied in adult male Sprague-Dawley rats. CBG was measured either by a homologous radioimmunoassay (RIA) or by a binding assay (BA) using 3H-corticosterone. Exposure of adult male rats to a severe stressor such as immobilization (IMO) for 1 h did...

journal_title：Endocrine

authors： Martí O,Martín M,Gavaldà A,Giralt M,Hidalgo J,Hsu BR,Kuhn RW,Armario A

更新日期：1997-04-01 00:00:00

abstract：:Prolactinomas are the most common secretory pituitary tumors; however, their pathogenesis is unclear. In order to explore the pathogenesis of prolactinomas, we used fiber-optic BeadArray to examine gene expression profiles in five prolactinomas compared with three normal pituitaries. Three down-regulated genes and one...

journal_title：Endocrine

authors： Jiang Z,Gui S,Zhang Y

更新日期：2010-12-01 00:00:00

abstract：:Persistent hyperglycemia is associated with chronic oxidative stress which contributes to the development and progression of diabetes-associated complications. The sensitivity of pancreatic β-cells to oxidative stress has been attributed to their low content of antioxidants compared with other tissues. Bioactive compo...

journal_title：Endocrine

authors： Prasath GS,Sundaram CS,Subramanian SP

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Glucose and lipid disturbances, as well as higher tendency to atherosclerosis, are observed in women with polycystic ovary syndrome (PCOS). Thyroid hormones action has long been recognized as an important determinant of glucose and lipid homeostasis. Some studies suggest that even in euthyroid subjects, thyro...

journal_title：Endocrine

authors： Adamska A,Krentowska A,Łebkowska A,Hryniewicka J,Leśniewska M,Adamski M,Kowalska I

更新日期：2019-07-01 00:00:00

abstract：:First-line treatment of patients with growth hormone secreting adenomas is surgical resection. Disease control can be obtained by surgery (one or multiple steps), in case followed by medical treatment or adjuvant radiation therapy (radiosurgery or radiotherapy). The impact of pre-surgical treatment with somatostatin a...

journal_title：Endocrine

authors： Bacigaluppi S,Gatto F,Anania P,Bragazzi NL,Rossi DC,Benvegnu G,Nazzari E,Spaziante R,Giusti M,Ferone D,Zona G

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:A large number of studies has investigated proopiomelanocortin processing in anterior pituitary corticotropes but little is known on proopiomelanocortin/ACTH degradation within these cells. The ubiquitin-proteasome system is an intracellular protein degradation pathway which has garnered considerable interest i...

journal_title：Endocrine

authors： Sesta A,Cassarino MF,Cavagnini F,Pecori Giraldi F

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:Adrenal myelolipoma is an invariably benign neoplasm of the adrenal gland that is the second most common primary adrenal incidentaloma following adrenocortical adenomas. It is composed of elements of adipose tissue and extramedullary hematopoiesis. Hypotheses on stem cells and hormonal factors have been fo...

journal_title：Endocrine

authors： Decmann Á,Perge P,Tóth M,Igaz P

更新日期：2018-01-01 00:00:00

abstract：:Retinol binding protein 4 (RBP4) is a novel adipocyte-secreted protein that contributes to systemic insulin resistance. Experiments in mice suggest that elevated RBP4 causes insulin resistance. In the present study, we determined serum RBP4 concentration and evaluated its association with insulin resistance in women w...

journal_title：Endocrine

authors： Weiping L,Qingfeng C,Shikun M,Xiurong L,Hua Q,Xiaoshu B,Suhua Z,Qifu L

更新日期：2006-12-01 00:00:00

abstract：:AdipoR1 is one of the adiponectin receptors which are important for adiponectin signaling. Because adiponectin is a candidate gene for common obesity, it is also hypothesized that variations in AdipoR1 may be involved in the development of complex obesity. Therefore, we designed an association study for the AdipoR1 ge...

journal_title：Endocrine

authors： Beckers S,de Freitas F,Zegers D,Mertens IL,Verrijken A,Van Camp JK,Van Gaal LF,Van Hul W

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:Mutant hypothyroid mouse models have recently shown that thyroid hormone is critical for skeletal development during an important prepubertal growth period. Additionally, thyroid hormone negatively regulates total body fat, consistent with the well-established effects of thyroid hormone on energy and fat metabo...

journal_title：Endocrine

authors： Lindsey RC,Mohan S

更新日期：2017-04-01 00:00:00

abstract：:Variations in the fat mass and obesity-associated (FTO) gene have recently been associated with obesity and type 2 diabetes mellitus among different ethnic populations. Given that the phenotype of polycystic ovary syndrome (PCOS) overlaps with obesity and type 2 diabetes, we hypothesize that the common rs9939609 varia...

journal_title：Endocrine

authors： Yan Q,Hong J,Gu W,Zhang Y,Liu Q,Su Y,Zhang Y,Li X,Cui B,Ning G

更新日期：2009-12-01 00:00:00

abstract：:Follicle-stimulating hormone is synthesized and secreted as a mixture of heterogeneous isoforms that differ from each other in carbohydrate structure, biological potency, and plasma half-life. The relative abundance of the FSH isoforms will depend on the endocrine status of the donor at the time of sample collection. ...

journal_title：Endocrine

authors： Olivares A,Söderlund D,Castro-Fernández C,Zariñán T,Zambrano E,Méndez JP,Ulloa-Aguirre A

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:An increasing body of evidence suggests that dipeptidyl-peptidase 4 (DPP-4) inhibitors could play a role in the development of bullous pemphigoid. The knowledge regarding this association is based on case reports, pharmacovigilance database analyses, and observational studies. Data from randomized clinical tria...

journal_title：Endocrine

authors： Silverii GA,Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

更新日期：2020-09-01 00:00:00

abstract：:Hypoxia is well known to decrease appetite and weight gain in growing rats, and to induce weight loss in humans. It has been hypothesized that this is mediated by a change in ghrelin, an orexigenic peptide synthesized and released primarily from the stomach. Rats were exposed to hypoxia for 7 d as neonates (birth-7 d ...

journal_title：Endocrine

authors： Raff H

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To evaluate whether losartan is able to induce beige adipocytes formation, focusing on the thermogenic gene expression and adipocyte remodeling in the subcutaneous white adipose tissue of diet-induced obese mice. METHODS:Male C57BL/6 mice received a control diet (10% energy as lipids) or a high-fat diet (50% e...

journal_title：Endocrine

authors： Graus-Nunes F,Rachid TL,de Oliveira Santos F,Barbosa-da-Silva S,Souza-Mello V

更新日期：2017-03-01 00:00:00

abstract：:Silent information regulator T1 (SIRT1) plays several key roles in the regulation of lipid and glucose homoeostasis. In this study, we investigated the potential role of SIRT1 in hyperuricemia and explored possible mechanisms. Significant hyperuricemia was detected in C57BL/6 mice treated with oxonate and yeast polysa...

journal_title：Endocrine

authors： Wang J,Zhu XX,Liu L,Xue Y,Yang X,Zou HJ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Surgical procedures are associated with activation of the hypothalamic-pituitary-adrenal axis (HPA). Studies examining HPA dynamics peri-operatively are limited and the modulating influence of peri-operatively administered glucocorticoids on that is not well established. This investigation examined alteratio...

journal_title：Endocrine

authors： El-Sibai K,Rajpal A,Al-Aridi R,Selman WR,Arafah BM

更新日期：2017-10-01 00:00:00

abstract：:In this study we analyzed whether corticosterone synthesis is involved in the regulation of adrenal gland type II deiodinase (AG-D2) activity during acute cold exposure. Two well-known inhibitors of steroidogenesis, aminoglutethimide (AGT) and metyrapone (MTP), were administered to male Wistar rats maintained either a...

journal_title：Endocrine

authors： Anguiano B,Valverde C

更新日期：2001-06-01 00:00:00

abstract：:Inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) is considered as a major predictor of cardiovascular events. Apolipoprotein B (ApoB) directly reflects the number of plasma atherogenic lipoproteins, and may play a major role in vascular inflammation. We aimed to assess whether an association between ...

journal_title：Endocrine

authors： Xu W,Li R,Zhang S,Gong L,Wang Z,Ren W,Xia C,Li Q

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:A promising radiopharmaceutical (99m)Tc-HYNIC-TOC ((99m)Tc-HYNIC-Octreotide) can be applied for somatostatin receptor scintigraphy with the potential to replace Indium-111 labeled somatostatin analogus. Here we evaluate whether orbital (99m)Tc-HYNIC-TOC scintigraphy can be used as a Graves' ophthalmopathy (GO...

journal_title：Endocrine

authors： Sun H,Jiang XF,Wang S,Chen HY,Sun J,Li PY,Ning G,Zhao YJ

更新日期：2007-06-01 00:00:00

abstract：:Recent animal studies support close associations of Periostin with hepatosteatosis and steatohepatitis. This study is to evaluate the role of serum periostin in non-alcoholic fatty liver disease (NAFLD). A hospital-based age-/sex-matched case-control study was conducted. Binary logistic regression and receiver operati...

journal_title：Endocrine

authors： Zhu JZ,Zhu HT,Dai YN,Li CX,Fang ZY,Zhao DJ,Wan XY,Wang YM,Wang F,Yu CH,Li YM

更新日期：2016-01-01 00:00:00

abstract：:The comparative efficacy and safety profiles of selected daily 1000 IU, weekly 7000 IU and monthly 30,000 IU vitamin D 3-not previously investigated-will be evaluated. Here, a prospective, randomized clinical trial, comparing efficacy and safety of a daily single dose of 1000 IU (group A) to a once-weekly 7000 IU dose...

journal_title：Endocrine

authors： Takács I,Tóth BE,Szekeres L,Szabó B,Bakos B,Lakatos P

更新日期：2017-01-01 00:00:00

abstract：:Our aim was to investigate body composition changes, epicardial adipose tissue thickness (EATT), serum omentin-1 levels, and the relationship among them along with some atherosclerosis markers in overt hypothyroidism. Twenty-eight newly diagnosed overt hypothyroid patients were evaluated before and after 6 months of t...

journal_title：Endocrine

authors： Cerit ET,Akturk M,Altinova AE,Tavil Y,Ozkan C,Yayla C,Altay M,Demirtas C,Cakir N

更新日期：2015-05-01 00:00:00

abstract：:Regular endurance exercise promotes metabolic and oxidative changes in skeletal muscle. Overexpression of interleukin-15 (IL-15) in mice exerts similar metabolic changes in muscle as seen with endurance exercise. Muscular IL-15 production has been shown to increase in mice after weeks of regular endurance running. Wit...

journal_title：Endocrine

authors： Rinnov A,Yfanti C,Nielsen S,Akerström TC,Peijs L,Zankari A,Fischer CP,Pedersen BK

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Growth hormone deficiency (GHD) is a condition associated with increased cardiovascular risk and insulin-resistance. Oxidative stress (OS) could be a mechanism underlying both these phenomena. In order to investigate plasma antioxidant defenses in such condition, we evaluated adults with GHD, compar...

journal_title：Endocrine

authors： Mancini A,Di Segni C,Bruno C,Olivieri G,Guidi F,Silvestrini A,Meucci E,Orlando P,Silvestri S,Tiano L,Pontecorvi A

更新日期：2018-01-01 00:00:00

abstract：:We have shown that gonadotrophs synthesize and secrete immunoreactive calcitonin (CT)-like peptide, and CT is a potent inhibitor of prolactin (PRL) secretion and gene transcription. CT cDNA cloned from LssT2 cells (pit-CT cDNA) exhibits 99% homology with mouse CT cDNA sequence, but exhibits four mismatches in the codi...

journal_title：Endocrine

authors： Kulkarni-Paranjape T,Shah GV

更新日期：2007-06-01 00:00:00

abstract：:Adult-onset growth-hormone (GH) deficiency (GHD) is a rare disorder, which most commonly results from pituitary or peripituitary tumors and their treatment, and is characterized by alterations in body composition, carbohydrate and lipid metabolism, bone mineral density, cardiovascular risk profile and quality of life,...

journal_title：Endocrine

authors： Ramos-Leví AM,Marazuela M

更新日期：2018-05-01 00:00:00

abstract：:Steroidogenic factor-1 (SF-1) is a transcription factor involved in regulation of steroidogenic enzymes. Recent evidence indicates that SF-1 is also important in the anterior pituitary gland, where it may influence gene expression in gonadotropes. We isolated a cDNA encoding ovine SF-1 and demonstrated that the SF-1 g...

journal_title：Endocrine

authors： Turzillo AM,Quirk CC,Juengel JL,Nett TM,Clay CM

更新日期：1997-06-01 00:00:00

abstract：:External ATP is believed to initiate and propagate Ca(2+) signals co-ordinating the insulin release pulses within and among the different islets in the pancreas. The possibility that islet endothelial cells participate in this process was evaluated by comparing the effects on [Ca(2+)](i) of purinoceptor activation in ...

journal_title：Endocrine

authors： Hellman B,Jansson L,Dansk H,Grapengiesser E

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Parathyroid cancer is a rare tumor associated with poor prognosis particularly when disseminated. While chemotherapy and/or radiotherapy are of no clinical value in disseminated disease, immunotherapy should be considered. SUBJECT AND RESULTS:A patient with CDC73-associated metastatic parathyroid carcinoma was...

journal_title：Endocrine

authors： Sarquis M,Marx SJ,Beckers A,Bradwell AR,Simonds WF,Bicalho MAC,Daly AF,Betea D,Friedman E,De Marco L

更新日期：2020-01-01 00:00:00