Long-term remission of disseminated parathyroid cancer following immunotherapy.

Abstract:

PURPOSE:Parathyroid cancer is a rare tumor associated with poor prognosis particularly when disseminated. While chemotherapy and/or radiotherapy are of no clinical value in disseminated disease, immunotherapy should be considered. SUBJECT AND RESULTS:A patient with CDC73-associated metastatic parathyroid carcinoma was treated with combined anti-hPTH immunotherapy and surgery. CONCLUSIONS:Following five courses of anti-hPTH immunotherapy and subsequent surgery, a 12-year long remission of disseminated parathyroid cancer is reported. This case further supports the ever-expanding spectrum of cancers that may benefit from immunotherapy.

journal_name

Endocrine

journal_title

Endocrine

authors

Sarquis M,Marx SJ,Beckers A,Bradwell AR,Simonds WF,Bicalho MAC,Daly AF,Betea D,Friedman E,De Marco L

doi

10.1007/s12020-019-02136-z

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

204-208

issue

1

eissn

1355-008X

issn

1559-0100

pii

10.1007/s12020-019-02136-z

journal_volume

67

pub_type

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