Prolactin-regulated apoptosis of Nb2 lymphoma cells: pim-1, bcl-2, and bax expression.

abstract：PURPOSE:Metabolic syndrome (MetS) is a constellation of clinical factors that indicates elevated risk of diabetes. It is diagnosed based on three or more abnormalities in its components. This does not take into account that MetS can likely present as a continuum of risk. We aim to develop a MetS severity score and asse...

journal_title：Endocrine

authors： Low S,Khoo KCJ,Wang J,Irwan B,Sum CF,Subramaniam T,Lim SC,Wong TKM

更新日期：2019-07-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroid glands, the anterior pituitary, and the endocrine pancreas. Our patient was a 58-year-old man who manifested typical features of MEN-1 including primary hyperparathyroidism, lung carcinoid, and lipom...

journal_title：Endocrine

authors： Nishiuchi T,Imachi H,Murao K,Fujiwara M,Muraoka T,Kikuchi F,Nishiuchi Y,Kushida Y,Haba R,Ishida T

更新日期：2009-08-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) and somatostatin are the most important hypothalamic neurohormones controlling growth hormone (GH) secretion. Several neurotransmitters and neuropeptides also play an important role in the control of GH secretion, mainly acting via modulation of GHRH and somatostatin. In the pas...

journal_title：Endocrine

authors： Arvat E,Gianotti L,Giordano R,Broglio F,Maccario M,Lanfranco F,Muccioli G,Papotti M,Graziani A,Ghigo E,Deghenghi R

更新日期：2001-02-01 00:00:00

abstract：:Homozygous Klotho mutant (kl-/-) mice exhibit a variety of phenotypes resembling human aging, including arteriosclerosis, infertility, skin atrophy, osteoporosis, and short life span. Calcium abnormality, one of the phenotypes in kl-/- mice, is thought to be due to the elevated gene expression of 25-hydroxyvitamin D3 ...

journal_title：Endocrine

authors： Imai M,Ishikawa K,Matsukawa N,Kida I,Ohta J,Ikushima M,Chihara Y,Rui X,Rakugi H,Ogihara T

更新日期：2004-12-01 00:00:00

abstract：:Bone metabolism disorder has been identified to play a vital role in the pathogenesis of glucocorticoid-induced osteoporosis (GIOP). The local renin-angiotensin system (RAS) in bone is newly defined to be closely related to the bone metabolism. However, it is unknown whether the local RAS is involved in GIOP. Adult ma...

journal_title：Endocrine

authors： Yongtao Z,Kunzheng W,Jingjing Z,Hu S,Jianqiang K,Ruiyu L,Chunsheng W

更新日期：2014-11-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is significantly affected by environmental regulators impacting on genetic predisposition. Lifestyle changes can significantly modulate the phenotype of this disease. Diet, exercise, smoking, stress, and other factors adversely affect reproductive outcomes in PCOS. These influences can...

journal_title：Endocrine

authors： Norman RJ,Homan G,Moran L,Noakes M

更新日期：2006-08-01 00:00:00

abstract：:Recent animal studies support close associations of Periostin with hepatosteatosis and steatohepatitis. This study is to evaluate the role of serum periostin in non-alcoholic fatty liver disease (NAFLD). A hospital-based age-/sex-matched case-control study was conducted. Binary logistic regression and receiver operati...

journal_title：Endocrine

authors： Zhu JZ,Zhu HT,Dai YN,Li CX,Fang ZY,Zhao DJ,Wan XY,Wang YM,Wang F,Yu CH,Li YM

更新日期：2016-01-01 00:00:00

abstract：:Interleukin 15 (IL-15) has recently been proposed as a myokine involved in regulating lipid metabolism. We investigated the effect of exercise training on IL-15 content in skeletal muscle and expression of IL-15 receptor (IL-15R) in adipose tissue of obese rats. After 12 weeks of a high-fat diet, obese rats underwent ...

journal_title：Endocrine

authors： Yang H,Chang J,Chen W,Zhao L,Qu B,Tang C,Qi Y,Zhang J

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:The evaluation of skeletal fragility in Cushing's syndrome (CS) is a clinical challenge, since dual-energy X-ray absorptiometry (DXA) does not capture abnormalities in bone microstructure induced by glucocorticoid excess. Hypercortisolism was shown to increase bone marrow adiposity, but it is still unknown whet...

journal_title：Endocrine

authors： Ferraù F,Giovinazzo S,Messina E,Tessitore A,Vinci S,Mazziotti G,Lania A,Granata F,Cannavò S

更新日期：2020-01-01 00:00:00

abstract：:Variants of growth hormone (GH) are present in most vertebrates. Chicken GH (cGH) undergoes posttranslational modifications that contribute to its structural diversity. Although the 22-kDa form of GH is the most abundant, some other variants have discrete bioactivities that may not be shared by others. The proportion ...

journal_title：Endocrine

authors： Martínez-Coria H,López-Rosales LJ,Carranza M,Berumen L,Luna M,Arámburo C

更新日期：2002-03-01 00:00:00

abstract：:To examine the effects of a structured group-based education programme, patient empowerment programme (PEP), compared with usual care on 2-year changes in patient-reported outcomes (PRO) in patients with diabetes mellitus (DM). A prospective observational study of 715 patients (PEP/non-PEP: 390/325) was conducted to c...

journal_title：Endocrine

authors： Wong CK,Lam CL,Wan EY,Chan AK,Pak CH,Chan FW,Wong WC

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:Negative-pressure wound therapy (NPWT) is an adjunct modality in diabetic foot ulcerations (DFUs). Randomized controlled trials (RCTs) have shown its advantage over standard approaches; however, data from observational studies remain scarce.We performed a systematic review of observational non-RCTs evaluating N...

journal_title：Endocrine

authors： Rys P,Borys S,Hohendorff J,Zapala A,Witek P,Monica M,Frankfurter C,Ludwig-Slomczynska A,Kiec-Wilk B,Malecki MT

更新日期：2020-04-01 00:00:00

abstract：:RECK (reversion-inducing cysteine-rich protein with Kazal motifs) is a membrane-anchored glycoprotein which regulates MMP2 and MMP9 activity and has been proposed to play a role in embryo implantation while misexpression of RECK has been associated with a variety of carcinomas. Unfortunately, understanding on the ster...

journal_title：Endocrine

authors： Zhang X,Healy C,Nothnick WB

更新日期：2012-08-01 00:00:00

abstract：:The peroxisome proliferator-activated receptors (PPARs)-α, -β/δ, and -γ are the ligand-activated transcription factors that function as the master regulators of glucose, fatty acid and lipoprotein metabolism, inflammation, and atherosclerosis. Our aim was to test the association between ten single nucleotide polymorph...

journal_title：Endocrine

authors： Gu SJ,Chen DH,Guo ZR,Zhou ZY,Hu XS,Wu M

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Hormonal status and menopause affect human macrophage function and cardiometabolic risk. In polycystic ovary syndrome (PCOS) patients the cardiometabolic risk increases through mechanisms that are largely unknown. We tested the hypotheses that macrophage activation is influenced by menstrual cycle and that ovar...

journal_title：Endocrine

authors： Tedesco S,Adorni MP,Ronda N,Cappellari R,Mioni R,Barbot M,Pinelli S,Plebani M,Bolego C,Scaroni C,Bernini F,Fadini GP,Cignarella A

更新日期：2019-11-01 00:00:00

abstract：:The therapeutic activity of 131I administered to patients with Graves' disease can be calculated by means of Marinelli's formula. The thyroidal iodine uptake (131IUmax) needed for the calculation is usually determined with the use of 131I. The purpose of the paper was to estimate 131IUmax on the basis of technetium up...

journal_title：Endocrine

authors： Szumowski P,Mojsak M,Abdelrazek S,Sykała M,Amelian-Fiłonowicz A,Jurgilewicz D,Myśliwiec J

更新日期：2016-12-01 00:00:00

abstract：:Aging can be defined as a progressive decline in the ability of the organism to resist stress, damage, and disease. Although there are currently over 300 theories to explain the aging phenomenon, it is still not well understood why organisms age and why the aging process can vary so much in speed and quality from indi...

journal_title：Endocrine

authors： Frisard M,Ravussin E

更新日期：2006-02-01 00:00:00

abstract：:Aging could be due to the accumulation of oxidative damage. On the other hand, growth hormone (GH) and estrogen deficiency induce deleterious effects on different tissues, and hormonal replacement could counteract these effects. We have investigated whether GH and estrogen administration modify some parameters related...

journal_title：Endocrine

authors： Castillo C,Salazar V,Ariznavarreta C,Vara E,Tresguerres JA

更新日期：2005-02-01 00:00:00

abstract：:The A1 adenosine receptor (A1AR) exerts important biological effects in the mammalian biology. To provide insights into the role A1AR action in human physiology, we characterized the pharmacologic properties of the human A1AR, examined somatic sites of A1AR gene expression, and identified the chromosomal location of t...

journal_title：Endocrine

authors： Rivkees SA,Lasbury ME,Stiles GS,Henegariu O,Curtis C,Vance G

更新日期：1995-09-01 00:00:00

abstract：:We aimed to investigate different enhancement patterns of solid thyroid nodules on contrast-enhanced ultrasound (CEUS) and then to evaluate the corresponding diagnostic performance in the differentiation of benign and malignant nodules with and without enhancement. 229 solid thyroid nodules in 196 patients who had und...

journal_title：Endocrine

authors： Wu Q,Wang Y,Li Y,Hu B,He ZY

更新日期：2016-08-01 00:00:00

abstract：:There are no data about the optimal supplementation therapy in HIV-infected patients with vitamin D (25OHD) deficiency. The aim of this study was to assess the effect of an oral monthly dose of 16,000 IU calcidiol. We performed a longitudinal cohort study of 365 HIV-infected patients (24 % females) was with sequential...

journal_title：Endocrine

authors： Bañón S,Rosillo M,Gómez A,Pérez-Elias MJ,Moreno S,Casado JL

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:The hyperthermal liquid, spray and smog caused by energy-based surgical devices (EBDs) may be the potential risk factors for recurrent laryngeal nerve (RLN) thermal injury, but not been reported previously. We aim to demonstrated it both in thyroid surgeries and animal experiments. METHODS:321 thyroid patients...

journal_title：Endocrine

authors： Yu X,Liu C,Yan M,Gong W,Wang Y

更新日期：2020-08-10 00:00:00

abstract：:We validated the effect of prolactin-releasing peptide (PrRP) on prolactin (PRL) secretion from rat anterior pituitary cells in in vitro culture. We found that culture conditions considerably influenced the response of the anterior pituitary cells to PrRP. Longer culture term (4 d) was required to obtain better respon...

journal_title：Endocrine

authors： Kawamata Y,Fujii R,Fukusumi S,Habata Y,Hosoya M,Hinuma S,Kitada C,Onda H,Nishimura O,Fujino M

更新日期：2000-06-01 00:00:00

abstract：:Remarkable decreases in growth hormone (GH) secretion accompany healthy aging. The pathophysiology of this hyposomatotropism is confounded by concurrent changes in body composition (with increased visceral fat), physiological declines in estrogen and androgen concentrations, differences in gender responses to aging, a...

journal_title：Endocrine

authors： Veldhuis JD,Iranmanesh A,Weltman A

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:This study investigated trends in chronic glucocorticoid (GC) use in South Korea, and determined the association between chronic GC use and 5-year all-cause mortality. METHODS:A sample cohort was extracted from the South Korean National Health Insurance database. Patients prescribed a continuous dose of GC for...

journal_title：Endocrine

authors： Oh TK,Song IA

更新日期：2020-09-01 00:00:00

abstract：:In glucocorticoid-induced osteoporosis (GIO), both bone formation and resorption are altered, however, with a relative prevalence of resorption, consistent with the positive results that have been reported with bisphosphonate treatment. Many studies have investigated the effect of bisphosphonates (BPs), a widely used ...

journal_title：Endocrine

authors： Rossini M,Orsolini G,Viapiana O,Adami S,Gatti D

更新日期：2015-08-01 00:00:00

abstract：:To evaluate the role of central subfield thickness (CST), cube average thickness (CAT), and cube volume (CV) as imaging biomarkers for severity of diabetic retinopathy within the ETDRS-based grades of retinopathy using spectral domain optical coherence tomography (SD-OCT). This study aims to evaluate the role of macul...

journal_title：Endocrine

authors： Saxena S,Caprnda M,Ruia S,Prasad S,Ankita,Fedotova J,Kruzliak P,Krasnik V

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:Present study aims to explore the pathophysiological role of microRNA (miR)-29a in the process of obesity-related cardiomyopathy in human subjects and mice. METHODS:The expression level of circulating exosomal miR-29a was measured in 37 lean and 30 obese human subjects, and correlated with cardiac parameters. ...

journal_title：Endocrine

authors： Li F,Zhang K,Xu T,Du W,Yu B,Liu Y,Nie H

更新日期：2019-03-01 00:00:00

abstract：:Hypopituitarism reduces life expectancy and increases the risk of cardiovascular and cerebrovascular diseases, as well as death. Abnormalities in the cardiovascular system may be independently related to GH deficiency (GHD). The aim of this study was to prospectively investigate coronary flow reserve and diastolic fun...

journal_title：Endocrine

authors： Boschetti M,Agosti S,Albanese V,Casalino L,Teti C,Bezante GP,Brunelli C,Albertelli M,Ferone D

更新日期：2017-02-01 00:00:00

abstract：:To investigate the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey. Seventy-six patients with CPHD were included in this study. Based on clinical, hormonal, and neuro-radiological data, relevant transcription factor genes were evaluated...

journal_title：Endocrine

authors： Baş F,Uyguner ZO,Darendeliler F,Aycan Z,Çetinkaya E,Berberoğlu M,Şiklar Z,Öcal G,Darcan Ş,Gökşen D,Topaloğlu AK,Yüksel B,Özbek MN,Ercan O,Evliyaoğlu O,Çetinkaya S,Şen Y,Atabek E,Toksoy G,Aydin BK,Bundak R

更新日期：2015-06-01 00:00:00