Exosomal microRNA-29a mediates cardiac dysfunction and mitochondrial inactivity in obesity-related cardiomyopathy.

abstract：:The original version of this article unfortunately contained a mistake in given and family names of all the authors. ...

journal_title：Endocrine

authors： Di Mario C,Petricca L,Gigante MR,Barini A,Barini A,Varriano V,Paglionico A,Cattani P,Ferraccioli G,Tolusso B,Gremese E

更新日期：2019-02-01 00:00:00

abstract：:To determine whether murine mammary growth is modulated by local insulin-like growth factor-1 (IGF-1) production, expression of recombinant IGF-1 was directed to the mammary glands of transgenic mice using an ovine prepro IGF-1 cDNA under control of the mouse mammary tumor virus-long terminal repeat (MMTV-LTR) promote...

journal_title：Endocrine

authors： Weber MS,Boyle PL,Corl BA,Wong EA,Gwazdauskas FC,Akers RM

更新日期：1998-06-01 00:00:00

abstract：:We investigated the expression and activity of cytosolic phospholipase A2 (cPLA2) in the corpus luteum during spontaneous and induced luteolysis in pseudopregnant rats. In both models, luteal PLA2 activity rose in association with functional regression and persisted during the following structural regression. Tissue c...

journal_title：Endocrine

authors： Kurusu S,Sakaguchi S,Kawaminami M,Hashimoto I

更新日期：2001-04-01 00:00:00

abstract：:A cohort of nine patients, mostly young adults, presented with a new sign/symptom of pheochromocytoma/paraganglioma: exercise-induced nausea and vomiting. The aims of this article are to introduce this sign/symptom and offer a possible hypothesis for the observation. Following a 2000 report from a paraganglioma patien...

journal_title：Endocrine

authors： King KS,Darmani NA,Hughes MS,Adams KT,Pacak K

更新日期：2010-06-01 00:00:00

abstract：:Peptide hormones are generated by proteolytic processing of their respective protein precursors by several prohormone processing proteases. The peptide hormone PTHrP is widely expressed in normal and malignant tissues, where proPTHrP undergoes proteolytic processing to generate PTHrP peptides with distinct biological ...

journal_title：Endocrine

authors： Deftos LJ,Burton D,Hastings RH,Terkeltaub R,Hook VY

更新日期：2001-07-01 00:00:00

abstract：PURPOSE:We aimed to evaluate the performance of structural magnetic resonance imaging (MRI)-based quantitative measurements at extraocular muscle (EOM), orbital fat (OF), and especially lacrimal gland (LG) in predicting response to glucocorticoid (GC) in patients with active and moderate-severe thyroid-associated ophth...

journal_title：Endocrine

authors： Hu H,Xu XQ,Chen L,Chen W,Wu Q,Chen HH,Zhu H,Shi HB,Wu FY

更新日期：2020-11-01 00:00:00

abstract：:Persistent organic pollutants (POPs) are endocrine-disrupting chemicals associated with metabolic syndrome and type 2 diabetes. In humans, little is known about their potential role on obesity. Adiponectin augments the effects of insulin on glucose homeostasis. The expression of adiponectin is reduced in obesity, insu...

journal_title：Endocrine

authors： Lim JE,Jee SH

更新日期：2015-02-01 00:00:00

abstract：:Aberrant accumulation of β-catenin plays an important role in a variety of human neoplasms. This can be caused by stabilizing mutation of β-catenin (CTNNB1, exon 3) or by mutation or deregulated expression of other components of the WNT/β-catenin signaling pathway. Accumulation of non-phosphorylated active β-catenin h...

journal_title：Endocrine

authors： Starker LF,Fonseca AL,Akerström G,Björklund P,Westin G,Carling T

更新日期：2012-12-01 00:00:00

abstract：:Administration of RU486 to late pregnant rats results in preterm delivery 24 h after treatment and the induction of a luteolytic process after labor. We investigated whether functional changes occurring within the corpora lutea after RU486 treatment were associated with morphologic features of apoptotic cell death. Ra...

journal_title：Endocrine

authors： Telleria CM,Goyeneche AA,Cavicchia JC,Stati AO,Deis RP

更新日期：2001-07-01 00:00:00

abstract：PURPOSE:Histologic and pTNM classification of differentiated thyroid cancer (DTC) is mandatory to assess risk of relapse, risk of death, and radioactive iodine administration. The impact of an expert central review of external pathology reports has not yet been reported. METHODS:Monocentric retrospective study to eval...

journal_title：Endocrine

authors： Hescot S,Sheikh-Alard H,Kordahi M,Hartl D,Hadoux J,Terroir M,Breuskin I,Baudin E,Scoazec JY,Schlumberger M,Al Ghuzlan A,Leboulleux S

更新日期：2020-10-31 00:00:00

abstract：:Thyroid hormone (TH) abnormalities are common in patients with diabetes mellitus (DM). These thyroid hormone abnormalities have been associated with inflammatory activity in several conditions but this link remains unclear in DM. We assessed the influence of subclinical inflammation in TH metabolism in euthyroid diabe...

journal_title：Endocrine

authors： Moura Neto A,Parisi MC,Alegre SM,Pavin EJ,Tambascia MA,Zantut-Wittmann DE

更新日期：2016-01-01 00:00:00

abstract：:Central circuits known to regulate food intake and energy expenditure also affect central cardiovascular regulation. For example, both the melanocortin and neuropeptide Y (NPY) peptide families, known to regulate food intake, also produce central hypertensive effects. Members of both families share a similar C-termina...

journal_title：Endocrine

authors： Gruber KA,Fan W,Akerberg H,Larhammar D,Chee MJ,Colmers WF,Cone RD

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:In order to study the association of G241R polymorphism of ICAM-1 gene with an earlier onset of Graves' disease (GD) and the susceptibility of K469E polymorphism to Graves' ophthalmopathy (GO) in Chinese population. STUDY DESIGN:A case-control and replication study was performed in 212 GD patients and 204 he...

journal_title：Endocrine

authors： Wang S,Sun H,Chen HY,Zhao ZF,Yang Y,Zhao YJ,Cui B,Ning G

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:PTEN and KLLN are two tumor suppressor genes located in 10q23, share a bidirectional promoter and have roles in carcinogenesis. Formerly, the role of PTEN mutations and KLLN epimutations were identified in incidence of thyroid lesions in individuals with Cowden syndrome, a rare autosomal dominant inherited diso...

journal_title：Endocrine

authors： Razavi SA,Modarressi MH,Yaghmaei P,Tavangar SM,Hedayati M

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To compare the effectiveness of liquid L-T4 (L-thyroxine) and tablet L-T4 in patients on L-T4 replacement or suppressive therapy. METHODS:The Cochrane Library, PubMed, Embase, and Web of Science databases were searched to identify relevant articles. All prospective or randomized controlled studies (RCTs) compa...

journal_title：Endocrine

authors： Laurent I,Tang S,Astère M,Wang KR,Deng S,Xiao L,Li QF

更新日期：2018-07-01 00:00:00

abstract：:Skeletal muscle atrophy is associated with type-1 diabetes. Skeletal muscle is the source of pro- and anti-inflammatory cytokines that can mediate muscle hypertrophy and atrophy, while resistance exercise can modulate both muscle mass and muscle cytokine expression. This study determined the effects of a 5-week resist...

journal_title：Endocrine

authors： Molanouri Shamsi M,Hassan ZH,Gharakhanlou R,Quinn LS,Azadmanesh K,Baghersad L,Isanejad A,Mahdavi M

更新日期：2014-05-01 00:00:00

abstract：:The androgen receptor (AR) plays a critical role in sexual differentiation and in the virilization of the male reproductive system. A clear understanding of AR expression at the early stages of sexual development will help elucidate the sensitivity of perinatal animals to endocrine modulation by external agents, such ...

journal_title：Endocrine

authors： You L,Sar M

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Rathke's cleft cysts (RCC) are lesions that arise from Rathke's pouch. Though frequently incidental, resulting symptoms in a minority of cases are indicators for surgical resection, which may prove beneficial. OBJECTIVE:To characterize a cohort of surgically-resected RCC cases at Oregon Health & Science Uni...

journal_title：Endocrine

authors： Langlois F,Manea A,Lim DST,McCartney S,Yedinak CG,Cetas JS,Fleseriu M

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effect of combining human parathyroid hormone (1-34) (PTH1-34; PTH) and menaquinone-4 (MK-4) on calvarial bone defect repair in osteopenic rats. METHODS:Fourteen week olds were subject to craniotomy for the establishment of osteopenic animal models fed through a chroni...

journal_title：Endocrine

authors： Weng SJ,Xie ZJ,Wu ZY,Yan DY,Tang JH,Shen ZJ,Li H,Bai BL,Boodhun V,Eric Dong XD,Yang L

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:Mutant hypothyroid mouse models have recently shown that thyroid hormone is critical for skeletal development during an important prepubertal growth period. Additionally, thyroid hormone negatively regulates total body fat, consistent with the well-established effects of thyroid hormone on energy and fat metabo...

journal_title：Endocrine

authors： Lindsey RC,Mohan S

更新日期：2017-04-01 00:00:00

abstract：:Bilirubin concentrations have been recently reported to be negatively associated with type 2 diabetes mellitus. We examined the association between bilirubin concentrations and gestational diabetes mellitus. In a prospective cohort study, 2969 pregnant women were recruited prior to 16 weeks of gestation and were follo...

journal_title：Endocrine

authors： Liu C,Zhong C,Zhou X,Chen R,Wu J,Wang W,Li X,Ding H,Guo Y,Gao Q,Hu X,Xiong G,Yang X,Hao L,Xiao M,Yang N

更新日期：2017-01-01 00:00:00

abstract：:We performed this study to investigate the prevalences of insulin resistance and metabolic syndrome (MetS) in a Chinese population with normal weight. We also examined whether fat mass is associated with insulin resistance and MetS in normal-weight individuals. Data were drawn from a cross-sectional study in China. Su...

journal_title：Endocrine

authors： Chen S,Chen Y,Liu X,Li M,Wu B,Li Y,Liang Y,Shao X,Holthöfer H,Zou H

更新日期：2014-08-01 00:00:00

abstract：:It is well known that TSH plays a major role in the secretion of thyroid hormones, maintenance of thyroid specific gene expression, and gland growth. In this study, we aimed to evaluate association between tests of thyroid functions (fT3, fT4, TSH) and differentiated thyroid carcinoma. 441 patients operated for nodula...

journal_title：Endocrine

authors： Gul K,Ozdemir D,Dirikoc A,Oguz A,Tuzun D,Baser H,Ersoy R,Cakir B

更新日期：2010-04-01 00:00:00

abstract：:We performed a meta-analysis to analyze the associations of depression with pre-diabetes (PreDM), undiagnosed diabetes (UDM), and previously diagnosed diabetes (PDM), and whether the association was affected by important study characteristics. We searched relevant articles published in PubMed and EMBASE up to August, ...

journal_title：Endocrine

authors： Chen S,Zhang Q,Dai G,Hu J,Zhu C,Su L,Wu X

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Growth hormone deficiency (GHD) is a condition associated with increased cardiovascular risk and insulin-resistance. Oxidative stress (OS) could be a mechanism underlying both these phenomena. In order to investigate plasma antioxidant defenses in such condition, we evaluated adults with GHD, compar...

journal_title：Endocrine

authors： Mancini A,Di Segni C,Bruno C,Olivieri G,Guidi F,Silvestrini A,Meucci E,Orlando P,Silvestri S,Tiano L,Pontecorvi A

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Thiazolidinediones (TZDs) improve peripheral insulin sensitivity, but the effect on arterial stiffness is less clear. The aim of the present study was to assess the differential effect of pioglitazone or rosiglitazone on arterial stiffness and plasma levels of adiponectin and leptin in patients with type 2 d...

journal_title：Endocrine

authors： Oz O,Tuncel E,Eryilmaz S,Fazlioglu M,Gul CB,Ersoy C,Ocak N,Dirican M,Cangur S,Baran I,Imamoglu S

更新日期：2008-02-01 00:00:00

abstract：:In randomized controlled trials (RCTs), more intensive glucose control in patients with type 2 diabetes leads to a modest (9%) reduction in major cardiovascular events (MACE), associated with a 20% reduction of kidney events and 13% reduction of eye events. The FDA issued guidance in 2008 led to the conduct of numerou...

journal_title：Endocrine

authors： Giugliano D,Maiorino MI,Bellastella G,Esposito K

更新日期：2018-05-01 00:00:00

abstract：:Steroid biosynthesis begins with the enzymatic conversion of cholesterol to pregnenolone. This reaction is catalyzed by the cytochrome P450 side-chain cleavage enzyme (P450scc), which is located on the matrix side of the inner mitochondrial membrane. Although the rate-limiting enzymatic step in steroidogenesis is the ...

journal_title：Endocrine

authors： Sandhoff TW,McLean MP

更新日期：1996-10-01 00:00:00

abstract：:Protocols for induction of hyperthyroidism in mice are highly variable and mostly involve short-term thyroid hormone (TH) treatment. In addition, little is known about a possible influence of sex on experimental TH manipulation. Here we analyzed the efficacy of intraperitoneal vs. oral levothyroxine (T4) administratio...

journal_title：Endocrine

authors： Engels K,Rakov H,Zwanziger D,Hönes GS,Rehders M,Brix K,Köhrle J,Möller LC,Führer D

更新日期：2016-10-01 00:00:00

abstract：:The effects of endomorphin-1 (EM1) on behavioral responses and on the hypothalamic-pituitary-adrenal system were investigated in mice. Locomotor activity was measured in an "open-field" apparatus, with parallel recording of the numbers of rearings and groomings. Different doses of the peptide (250 ng to 5 microg) were...

journal_title：Endocrine

authors： Bujdosó E,Jászberényi M,Tömböly C,Tóth G,Telegdy G

更新日期：2001-03-01 00:00:00