The CD105:CD106 microparticle ratio is CD106 dominant in polycystic ovary syndrome compared to type 2 diabetes and healthy subjects.

abstract：:The purpose of the study was to determine whether impaired beta-cell function exists in Chinese individuals within the normal range of glucose tolerance (NGT), and these individuals are predisposed to diabetes later in life. The cross-sectional study included 843 NGT subjects and 562 isolated impaired glucose toleranc...

journal_title：Endocrine

authors： Lin Z,Zhou J,Li X,Song L,Hou X,Tang J,Wang C,Jia W

更新日期：2015-02-01 00:00:00

abstract：:The androgen receptor (AR) plays a critical role in sexual differentiation and in the virilization of the male reproductive system. A clear understanding of AR expression at the early stages of sexual development will help elucidate the sensitivity of perinatal animals to endocrine modulation by external agents, such ...

journal_title：Endocrine

authors： You L,Sar M

更新日期：1998-12-01 00:00:00

abstract：:Erectile dysfunction (ED) is commonly associated with risk factors for cardiovascular disease, including diabetes. The prevalence of ED in diabetic patients is high--about 75% of diabetic men 60 yr of age or older had ED in one study. Endothelial dysfunction, accelerated atherosclerosis, and diabetic neuropathy likely...

journal_title：Endocrine

authors： Kloner RA

更新日期：2004-03-01 00:00:00

abstract：:AdipoR1 is one of the adiponectin receptors which are important for adiponectin signaling. Because adiponectin is a candidate gene for common obesity, it is also hypothesized that variations in AdipoR1 may be involved in the development of complex obesity. Therefore, we designed an association study for the AdipoR1 ge...

journal_title：Endocrine

authors： Beckers S,de Freitas F,Zegers D,Mertens IL,Verrijken A,Van Camp JK,Van Gaal LF,Van Hul W

更新日期：2013-02-01 00:00:00

abstract：:Fibromyalgia (FM) is a disease entity consisting of a heterogeneous cluster of symptoms that has thus far eluded identification of a causative etiology. The disease onset appears to follow physiological and/or psychological stressors and involves a subset of symptoms that are consistent with varied disorders found in ...

journal_title：Endocrine

authors： Shuer ML

更新日期：2003-10-01 00:00:00

abstract：:Steroid hormones regulate levels of gonadotropin mRNA in the pituitary, and gonadotropic hormones in plasma. To determine whether estrogen receptor alpha (ERalpha) mediates steroid negative feedback, wild type (WT) and estrogen receptor alpha knockout (ERalphaKO) mice of both sexes were gonadectomized and implanted wi...

journal_title：Endocrine

authors： Wersinger SR,Haisenleder DJ,Lubahn DB,Rissman EF

更新日期：1999-10-01 00:00:00

abstract：:Regular endurance exercise promotes metabolic and oxidative changes in skeletal muscle. Overexpression of interleukin-15 (IL-15) in mice exerts similar metabolic changes in muscle as seen with endurance exercise. Muscular IL-15 production has been shown to increase in mice after weeks of regular endurance running. Wit...

journal_title：Endocrine

authors： Rinnov A,Yfanti C,Nielsen S,Akerström TC,Peijs L,Zankari A,Fischer CP,Pedersen BK

更新日期：2014-03-01 00:00:00

abstract：:The possible association between low skeletal muscle mass and cardiovascular disease (CVD) risk factors necessitates estimation of muscle mass even in subjects with normal body mass index (BMI). This study was aimed to investigate optimal cutoffs for skeletal muscle mass reflecting CVD risk factors and to evaluate the...

journal_title：Endocrine

authors： Kim Y,Han BD,Han K,Shin KE,Lee H,Kim TR,Cho KH,Kim DH,Kim YH,Kim H,Nam GE

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:This study investigated trends in chronic glucocorticoid (GC) use in South Korea, and determined the association between chronic GC use and 5-year all-cause mortality. METHODS:A sample cohort was extracted from the South Korean National Health Insurance database. Patients prescribed a continuous dose of GC for...

journal_title：Endocrine

authors： Oh TK,Song IA

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Recently, it has been confirmed that circulating miRNAs play an important role in disease pathogenesis and can be biomarkers of many autoimmune diseases. However, the knowledge about circulating miRNAs in Graves' disease (GD) is very limited. In this study, we aimed to identify circulating miRNAs as potential b...

journal_title：Endocrine

authors： Yao Q,Wang X,He W,Song Z,Wang B,Zhang J,Qin Q

更新日期：2019-07-01 00:00:00

abstract：:Thymic carcinoid is an important component of the tumor spectrum causing Ectopic ACTH Syndrome (EAS) and usually carries a poor prognosis. Efforts have been focused on exploring the mechanism of the excessive ACTH production in non-pituitary tumors, whereas few studies have reported the molecular events underlying the...

journal_title：Endocrine

authors： Liu RX,Wang WQ,Ye L,Bi YF,Fang H,Cui B,Zhou WW,Dai M,Zhang J,Li XY,Ning G

更新日期：2010-08-01 00:00:00

abstract：:The Metastatic progression of solid tumors, such as thyroid cancer is a complex process which involves various factors. Current understanding on the role of epithelial-mesenchymal transition (EMT) in thyroid carcinomas suggests that EMT is implicated in the progression from follicular thyroid cancer (FTC) and papillar...

journal_title：Endocrine

authors： Shakib H,Rajabi S,Dehghan MH,Mashayekhi FJ,Safari-Alighiarloo N,Hedayati M

更新日期：2019-12-01 00:00:00

abstract：:RECK (reversion-inducing cysteine-rich protein with Kazal motifs) is a membrane-anchored glycoprotein which regulates MMP2 and MMP9 activity and has been proposed to play a role in embryo implantation while misexpression of RECK has been associated with a variety of carcinomas. Unfortunately, understanding on the ster...

journal_title：Endocrine

authors： Zhang X,Healy C,Nothnick WB

更新日期：2012-08-01 00:00:00

abstract：:In this study we analyzed whether corticosterone synthesis is involved in the regulation of adrenal gland type II deiodinase (AG-D2) activity during acute cold exposure. Two well-known inhibitors of steroidogenesis, aminoglutethimide (AGT) and metyrapone (MTP), were administered to male Wistar rats maintained either a...

journal_title：Endocrine

authors： Anguiano B,Valverde C

更新日期：2001-06-01 00:00:00

abstract：INTRODUCTION:We retrospectively evaluated all patients with pituitary tumours treated in our department from 1/1/1997 to 01/11/2014. PATIENTS AND METHODS:Two hundred and fifteen patients (124 females, 91 males, mean age 50.9 years) were treated because of pituitary tumours. All patients underwent basal hormonal analys...

journal_title：Endocrine

authors： Askitis D,Tsitlakidis D,Müller N,Waschke A,Wolf G,Müller UA,Kloos C

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conformal, fractionated radiation therapy (XRT) is variably used as a treatment alternative for active acromegaly patients, usually, after failed pituitary surgery. Our objective was to evaluate the long-term efficacy and safety of XRT using strict criteria of biochemical control. SETTING, DESIG...

journal_title：Endocrine

authors： Gonzales-Virla B,Vargas-Ortega G,Martínez-Vázquez KB,de Lo Monteros ALE,Sosa-Erosa E,López-Félix B,Mendoza-Zubieta V,Mercado M

更新日期：2019-08-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Endocrine

authors： Poli R,Scatolini M,Grosso E,Maletta F,Gallo M,Liscia D,Nelva A,Cesario F,Forte G,Metovic J,Volante M,Arvat E,Papotti M

更新日期：2020-12-01 00:00:00

abstract：:Despite the majority of papillary thyroid microcarcinoma (PTMC) patients has benign clinical courses, some PTMCs have a clinical presentation similar to conventional papillary thyroid carcinoma (PTC). The aim of this study was to identify risk factors for lymph node metastasis at presentation and prognostic parameters...

journal_title：Endocrine

authors： Pisanu A,Saba A,Podda M,Reccia I,Uccheddu A

更新日期：2015-03-01 00:00:00

abstract：CONTEXT:To prepare for radioactive iodine therapy in post total thyroidectomy patients with well-differentiated thyroid cancer (WDTC), either thyroid hormone withdrawal (THW) or administration of recombinant human thyrotropin (rhTSH) can be performed. OBJECTIVE:Our objective is to compare quality of life (QoL) paramet...

journal_title：Endocrine

authors： Tang CYL,Thang SP,Zaheer S,Kwan CK,Ng DC

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Heparanase, galectin-3, and tissue factor (TF) are overexpressed in solid malignant thyroid tumors. We studied their expression in multinodular goiters (MNGs). DESIGN AND METHODS:Thyroid tissue specimens from 15 MNGs were obtained during surgery. mRNA expression for galectin-3, heparanase, and TF was assesse...

journal_title：Endocrine

authors： Buchs AE,Zehavi S,Sher O,Yeheskely E,Muggia-Sulam M,Sherman Y,Rapoport MJ

更新日期：2003-11-01 00:00:00

abstract：:To assess how early can estrogens induce female mating behaviors, rat pups 8-29 days old (D8-D29, respectively) were injected twice daily with estradiol benzoate (E) or oil (O) followed by progesterone (P) or oil, and then observed for the estrogen-dependent ear wiggling (EW) and lordosis in response to natural stimul...

journal_title：Endocrine

authors： Kow LM,Bogun M,Zhang Q,Pfaff DW

更新日期：2007-12-01 00:00:00

abstract：:We validated the effect of prolactin-releasing peptide (PrRP) on prolactin (PRL) secretion from rat anterior pituitary cells in in vitro culture. We found that culture conditions considerably influenced the response of the anterior pituitary cells to PrRP. Longer culture term (4 d) was required to obtain better respon...

journal_title：Endocrine

authors： Kawamata Y,Fujii R,Fukusumi S,Habata Y,Hosoya M,Hinuma S,Kitada C,Onda H,Nishimura O,Fujino M

更新日期：2000-06-01 00:00:00

abstract：PURPOSE:To assess the effectiveness and safety of myoinositol for patients with PCOS. METHODS:In this meta-analysis, data from randomized controlled trials are obtained to assess the effects of myoinositol vs. placebo or western medicine in women with PCOS. The study's registration number is CRD42017064563. The primar...

journal_title：Endocrine

authors： Zeng L,Yang K

更新日期：2018-01-01 00:00:00

abstract：:The peroxisome proliferator-activated receptors (PPARs)-α, -β/δ, and -γ are the ligand-activated transcription factors that function as the master regulators of glucose, fatty acid and lipoprotein metabolism, inflammation, and atherosclerosis. Our aim was to test the association between ten single nucleotide polymorph...

journal_title：Endocrine

authors： Gu SJ,Chen DH,Guo ZR,Zhou ZY,Hu XS,Wu M

更新日期：2015-02-01 00:00:00

abstract：:The role of membrane-associated tubulin in TRH receptor-G protein coupling was investigated with the use of compounds that influence tubulin function. TRH-stimulated G protein GTPase activity in GH(3) cell membranes was used to determine receptor-G protein coupling. TRH-stimulated GTPase activity was abolished by G(qα...

journal_title：Endocrine

authors： Ravindra R,Forman LJ,Patel SA

更新日期：1996-02-01 00:00:00

abstract：:The secreted hepatokine fetuin-A emerges as an independent predictor of type 2 diabetes in adulthood. The overall aims of this study were: (1) to investigate the associations of fetuin-A with adiposity and insulin resistance, as well as its relationship with adipokines, in prepubertal children, and, (2) to evaluate wh...

journal_title：Endocrine

authors： Murdolo G,Tortoioli C,Celi F,Bini V,Papi F,Brozzetti A,Falorni A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Wolfram syndrome (WFS) is a rare, monogenic neurodegenerative syndrome characterised by insulin requiring non-autoimmune diabetes mellitus (DM) and optic atrophy which are usually the earliest and commonest manifestations. However, there are other features which are under-recognized, adding to morbidity and ...

journal_title：Endocrine

authors： Das L,Rai A,Mavuduru R,Vaiphei K,Sharma A,Gupta V,Bhadada SK,Lodha S,Panda N,Bhansali A,Singh P,Dutta P

更新日期：2020-08-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a rare disease in which the most common endocrine manifestation is diabetes insipidus (DI). Data on anterior pituitary function in patients with LCH are limited. Thus, the present study investigated anterior pituitary function in LCH patients with DI via the evaluation of clinica...

journal_title：Endocrine

authors： Kurtulmus N,Mert M,Tanakol R,Yarman S

更新日期：2015-04-01 00:00:00

abstract：:The objective was to determine molecular genetic analysis of the TPO gene in Turkish children with iodide organification defect (IOD). Patients with a diagnosis of primary hypothyroidism were evaluated. Subjects having a definite diagnosis of autoimmune thyroiditis, thyroid gland dysplasia and, or iodine deficiency we...

journal_title：Endocrine

authors： Turkkahraman D,Alper OM,Pehlivanoglu S,Aydin F,Yildiz A,Luleci G,Akcurin S,Bircan I

更新日期：2010-02-01 00:00:00

abstract：:The aim is to study the association of estrogen receptor α (ERα) and estrogen receptor β (ERβ) gene polymorphisms and diplotypes with ovarian response to follicle-stimulating hormone (FSH) stimulation and the hormone levels [FSH, luteinizing hormone (LH), E2] at the third day of the menstrual cycle. Three hundred wome...

journal_title：Endocrine

authors： Lazaros L,Pamporaki C,Vlahos N,Takenaka A,Kitsou C,Kosmas I,Sofikitis N,Stefos T,Zikopoulos K,Hatzi E,Georgiou I

更新日期：2014-12-01 00:00:00